Methacrylic Acid

Methacrylic Acid

SCHEMBL29353183

C=C(C)C(=O)O.C=C(C)C(=O)OCCO.C=C(C)C(=O)OCCOC(=O)C(=C)C.C=CN1CCCC1=O

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28595629 0.99 POLB (0.34) THRBPOLBAPEX1HTTTDP1
SCHEMBL3141829 0.95 THRB (0.36) THRBPOLBAPEX1HTTTDP1
SCHEMBL28333248 0.91 THRB (0.41) THRBPOLBAPEX1HTTTDP1
SCHEMBL29353135 0.91 THRB (0.34) THRBPOLBAPEX1HTTTDP1
SCHEMBL11210985 0.91 ALDH1A1 (0.36) THRBPOLBAPEX1HTTTDP1
SCHEMBL14973716 0.90 THRB (0.34) THRBTSHR
Acrylamide SCHEMBL28703253 0.89 THRB (0.32) THRBPOLBAPEX1HTTTDP1
Methacrylic Acid SCHEMBL5992325 0.86 THRB (0.35) THRBTSHRCA1CA2
Methacrylic Acid SCHEMBL10598884 0.86 TSHR (0.51) THRBPOLBAPEX1HTTTDP1
Methacrylic Acid SCHEMBL17823491 0.85 TSHR (0.53) THRBPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230384482-A1 SANDWICH COLORED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-30 US claimed
US-11278503-B2 Pharmaceutical compositions comprising semifluorinated alkanes for the treatment of contact lense-related conditions NOVALIQ GMBH (DE) 2022-03-22 US claimed
US-20260137558-A1 OPHTHALMIC DEVICE Able Tx Ltd. (IL) 2026-05-21 US disclosed
US-12629057-B2 System for collecting and utilizing health data MENICON CO., LTD. (JP) 2026-05-19 US disclosed
US-12629906-B2 System and method to manufacture a contact lens with an embedded element ALCON INC. (CH) 2026-05-19 US disclosed
WO-2026099827-A1 LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES ALCON INC. (CH) 2026-05-15 WO disclosed
US-20260132236-A1 LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES ALCON INC (CH) 2026-05-14 US disclosed
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-05-14 US disclosed
EP-4304842-B1 METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES ALCON INC (CH) 2026-05-06 EP disclosed
US-20260118700-A1 DIFFRACTIVE MULTIFOCAL CONTACT LENS ALCON INC (CH) 2026-04-30 US disclosed
EP-3976381-B1 PAD TRANSFER PRINTING INSTRUMENT AND METHOD FOR MAKING COLORED CONTACT LENSES ALCON INC (CH) 2026-04-29 EP disclosed
EP-3976381-A1 PAD TRANSFER PRINTING INSTRUMENT AND METHOD FOR MAKING COLORED CONTACT LENSES Alcon Inc. (CH) 2022-04-06 EP disclosed
WO-2022061132-A1 OPHTHALMIC DEVICES FOR THE TREATMENT OR AMELIORATION OF DRY EYE DISEASE, AND RELATED METHODS OF USE THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2022-03-24 WO disclosed
US-11278503-B2 Pharmaceutical compositions comprising semifluorinated alkanes for the treatment of contact lense-related conditions NOVALIQ GMBH (DE) 2022-03-22 US disclosed
CN-114206849-A Therapeutic methods for treating non-infectious ocular immunoinflammatory disorders 斯格本斯眼科研究所有限公司 2022-03-18 CN disclosed
US-20220079877-A1 DEVICES AND METHODS FOR REDUCING CYSTINE CRYSTALS IN VIVO UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2022-03-17 US disclosed
WO-2022053791-A1 COLOURED CONTACT LENS COOPERVISION INTERNATIONAL LIMITED (GB) 2022-03-17 WO disclosed
US-20220075210-A1 CONTACT LENS COOPERVISION INTERNATIONAL LIMITED (GB) 2022-03-10 US disclosed
US-11256003-B2 Weekly and monthly disposable water gradient contact lenses ALCON INC. (CH) 2022-02-22 US disclosed
CN-109718376-B Ophthalmic product with anti-allergy and relieving effects 晶硕光学股份有限公司 2022-01-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629906-B2 System and method to manufacture a contact lens with an embedded element GCN1, RPL7, DSTN THRB 2824/4885POLB 2899/4885APEX1 3938/4885
US-20260132236-A1 LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES RAD51, ERCC1, LANCL2 THRB 824/4885POLB 4060/4885APEX1 2711/4885
US-12629057-B2 System for collecting and utilizing health data LAGE3, SUMO1, USP36 THRB 2401/4885POLB 3964/4885APEX1 4436/4885
US-20260137558-A1 OPHTHALMIC DEVICE IL2, ICOS, TRHDE THRB 246/4885POLB 4595/4885APEX1 4529/4885
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES CRYZ, CRYAB, CRYAA THRB 945/4885POLB 4215/4885APEX1 1760/4885
US-20260118700-A1 DIFFRACTIVE MULTIFOCAL CONTACT LENS DSG1, SDC1, DSP THRB 2841/4885POLB 3507/4885APEX1 2409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.