SCHEMBL29355287

SCHEMBL29355287

Nc1ccc(-c2ccc(-c3cc(-c4cccc(CN(CC(=O)[O-])CC(=O)[O-])n4)nc(-c4cccc(CN(CC(=O)[O-])CC(=O)[O-])n4)c3)cc2)cc1.[Eu+3].[Na+]

nearest known ligand 0.34

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SCN9A known ✓ Q15858 1/20 0.32
LTB4R Q15722 3/20 0.34
AOC3 Q16853 1/20 0.34
ALPL P05186 1/20 0.31
UCHL1 P09936 1/20 0.30
UCHL3 P15374 1/20 0.30
UCHL5 Q9Y5K5 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1784625 0.99 LTB4R (0.35) LTB4RAOC3SCN9AALPLUCHL1
SCHEMBL18112561 0.88 CYP19A1 (0.36) LTB4RAOC3MEN1ALDH1A1GAA
SCHEMBL13997750 0.87 LTB4R (0.41) LTB4RAOC3SCN9AALPLUCHL1
SCHEMBL9594349 0.87 LTB4R (0.41) LTB4RAOC3SCN9AALPLUCHL1
SCHEMBL18112512 0.86 CYP19A1 (0.35) LTB4RAOC3MEN1ALDH1A1GAA
SCHEMBL9296643 0.82 LTB4R (0.41) LTB4RAOC3ALPLUCHL1UCHL3
SCHEMBL1786817 0.81 CNR1 (0.34) SCN9AHSD17B10
SCHEMBL8755383 0.81 ALDH1A1 (0.40) LTB4RAOC3MEN1NPC1ALDH1A1
SCHEMBL1782379 0.81 ALDH1A1 (0.33) AOC3MEN1NPC1ALDH1A1MAPT
SCHEMBL7199262 0.79 TXN (0.39) MEN1ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741825-A1 TEST KIT Lifetrek Inc. (JP) 2026-05-13 EP disclosed
US-20260063554-A1 METHODS AND SYSTEMS FOR TIME-GATED FLUORESCENT-BASED DETECTION INSILIXA INC (US) 2026-03-05 US disclosed
US-20250231112-A1 METHODS AND SYSTEMS FOR TIME-GATED FLUORESCENT-BASED DETECTION INSILIXA, INC. 2025-07-17 US disclosed
US-20250216331-A1 OPTICAL MEASUREMENT DEVICE AND OPTICAL MEASUREMENT METHOD HAMAMATSU PHOTONICS K.K. (JP) 2025-07-03 US disclosed
US-12305097-B2 Fluorescent silica nanoparticles using silane-lanthanum-base complex composite and cross-linking reaction and method for manufacturing same AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2025-05-20 US disclosed
US-12287288-B2 Optical measurement device and optical measurement method HAMAMATSU PHOTONICS K.K. (JP) 2025-04-29 US disclosed
US-20250067734-A1 Fluorescent Cellulose Particles ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-02-27 US disclosed
CN-119510370-A Method and system for fluorescence detection based on time gating 因斯利克萨公司 2025-02-25 CN disclosed
WO-2025013724-A1 TEST KIT ライフトレック株式会社 2025-01-16 WO disclosed
CN-113924041-B Method and system for fluorescence detection based on time gating 因斯利克萨公司 2024-12-03 CN disclosed
US-20220276256-A1 METHODS FOR DETECTING ASSAY INTERFERENTS AND INCREASING DYNAMIC RANGE ABBOTT LABORATORIES 2022-09-01 US disclosed
WO-2022163124-A1 MEMBRANE FOR IMMUNOCHROMATOGRAPHIC ASSAYS, TEST STRIP FOR IMMUNOCHROMATOGRAPHIC ASSAYS, AND TEST METHOD 東洋濾紙株式会社 2022-08-04 WO disclosed
US-11371987-B2 Method of amplifying detection light using light-reflecting material, in immunochromatography DENKA COMPANY LIMITED (JP) 2022-06-28 US disclosed
EP-4010707-A1 METHODS FOR DETECTING ASSAY INTERFERENTS AND INCREASING DYNAMIC RANGE Abbott Laboratories (US) 2022-06-15 EP disclosed
US-11360029-B2 Methods and systems for time-gated fluorescent-based detection INSILIXA, INC. (US) 2022-06-14 US disclosed
US-20220151962-A1 NOVEL INHIBITORS OF HISTONE DEACETYLASE 10 DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2022-05-19 US disclosed
WO-2022037599-A9 CHLORIN DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, USE THEREOF, AND COMBINATION THEREOF WITH ULTRASOUND MEDICAL SYSTEM 广州易斯生物科技发展有限公司 2022-04-21 WO disclosed
WO-2022037599-A1 CHLORIN DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, USE THEREOF, AND COMBINATION THEREOF WITH ULTRASOUND MEDICAL SYSTEM 广州易斯生物科技发展有限公司 2022-02-24 WO disclosed
US-20220054636-A1 Chlorin Derivatives or Pharmaceutically Acceptable Salts Thereof, Preparation Method and Use Thereof, and Combination Thereof with an Ultrasonic Medical System GUANGZHOU EEC BIOTECH DEVELOPMENT CO., LTD. (CN) 2022-02-24 US disclosed
EP-3941900-A1 NOVEL INHIBITORS OF HISTONE DEACETYLASE 10 Deutsches Krebsforschungszentrum (DE) 2022-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220151962-A1 NOVEL INHIBITORS OF HISTONE DEACETYLASE 10 HDAC10, HDAC1, HDAC11 SCN9A 1326/4885LTB4R 4595/4885AOC3 3159/4885
US-20220054636-A1 Chlorin Derivatives or Pharmaceutically Acceptable Salts Thereof, Preparation Method and Use Thereof, and Combination Thereof with an Ultrasonic Medical System STAT6, JAK3, JAK1 SCN9A 4588/4885LTB4R 4708/4885AOC3 1956/4885
US-20260063554-A1 METHODS AND SYSTEMS FOR TIME-GATED FLUORESCENT-BASED DETECTION NT5C2, PER2, RYR2 SCN9A 861/4885LTB4R 3315/4885AOC3 3580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.