Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 9/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 8/20 | 0.64 |
| ▸ | ADRA2B | P18089 | 7/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.64 |
| ▸ | HTR1D | P28221 | 5/20 | 0.64 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.64 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | HRH2 | P25021 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.64 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11176814 | 0.90 | ADRA2A (0.79) | ADRA2AADRA2CADRA2BADRA1AHTR1D | |
| Clonidine SCHEMBL5983 | 0.80 | ADRA2A (1.00) | ADRA2AADRA2CADRA2BADRA1AHTR1D | |
| SCHEMBL4760243 | 0.80 | HTR1D (1.00) | ADRA2AADRA2CADRA2BADRA1AHTR1D | |
| Hydrochloric Acid SCHEMBL29384552 | 0.78 | HTR1D (0.97) | ADRA2AADRA2CADRA2BADRA1AHTR1D | |
| Clonidine SCHEMBL9838990 | 0.78 | ADRA2A (0.97) | ADRA2AADRA2CADRA2BADRA1AHTR1D | |
| Clonidine SCHEMBL2231324 | 0.78 | ADRA2A (1.00) | ADRA2AADRA2CADRA2BADRA1AHTR1D | |
| Clonidine SCHEMBL613364 | 0.78 | ADRA2A (0.97) | ADRA2AADRA2CADRA2BADRA1AHTR1D | |
| Clonidine SCHEMBL40752 | 0.78 | ADRA2A (1.00) | ADRA2AADRA2CADRA2BADRA1AHTR1D | |
| Clonidine SCHEMBL18050245 | 0.78 | ADRA2A (0.82) | ADRA2AADRA2CADRA2BADRA1AHTR1D | |
| SCHEMBL17887765 | 0.76 | HTR1D (0.79) | ADRA2AADRA2CADRA2BADRA1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230309480-A1 | METHODS OF INCREASING OUTCROSSING RATES IN GRAMINEAE | INTERNATIONAL RICE RESEARCH INSTITUTE (PH) | 2023-10-05 | — | — | US | claimed |
| EP-4199703-A1 | METHODS OF INCREASING OUTCROSSING RATES IN GRAMINEAE | International Rice Research Institute (PH) | 2023-06-28 | — | — | EP | claimed |
| WO-2022038536-A1 | METHODS OF INCREASING OUTCROSSING RATES IN GRAMINEAE | INTERNATIONAL RICE RESEARCH INSTITUTE (PH) | 2022-02-24 | — | — | WO | claimed |
| US-20260127545-A1 | SIMULATION MODEL GENERATION METHOD, SIMULATION MODEL GENERATION PROGRAM, AND SIMULATION MODEL GENERATION SYSTEM | PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) | 2026-05-07 | — | — | US | disclosed |
| US-12611461-B2 | Bioorthogonal compositions | TAMBO, INC. (US) | 2026-04-28 | — | — | US | disclosed |
| US-20260079462-A1 | METHOD OF MANAGING MANUFACTURING LINE | KIOXIA CORPORATION (JP) | 2026-03-19 | — | — | US | disclosed |
| US-20260072513-A1 | Sensory Control Method, Sensory Control System, Method For Generating Conversion Model, Conversion Model Generation System, Method For Converting Relational Expression, And Program | ALPS ALPINE CO LTD (JP) | 2026-03-12 | — | — | US | disclosed |
| WO-2026042565-A1 | AUTHENTICATION SYSTEM, INFORMATION PROCESSING METHOD FOR AUTHENTICATION SYSTEM, AND PROGRAM | フェリカネットワークス株式会社 | 2026-02-26 | — | — | WO | disclosed |
| US-12551959-B2 | Solder supply unit, solder piece manufacturing device, part mounting device, and production system | HIRATA CORPORATION (JP) | 2026-02-17 | — | — | US | disclosed |
| US-20260045791-A1 | ELECTRICAL LINE SELECTOR SYSTEM HAVING MULTIPLE SOURCES | RELECTRIFY HOLDINGS PTY LTD (AU) | 2026-02-12 | — | — | US | disclosed |
| US-12504826-B2 | Sensory control method, sensory control system, method for generating conversion model, conversion model generation system, method for converting relational expression, and program | ALPS ALPINE CO., LTD. (JP) | 2025-12-23 | — | — | US | disclosed |
| WO-2022091322-A1 | SERVER SELECTION DEVICE AND SERVER SELECTION SYSTEM | 三菱電機株式会社 | 2022-05-05 | — | — | WO | disclosed |
| WO-2022092199-A1 | ADHESIVE TAPE | 積水化学工業株式会社 | 2022-05-05 | — | — | WO | disclosed |
| US-20220119352-A1 | BIS-CYCLIC GUANIDINES AS ANTIBACTERIAL AGENTS | NATIONAL SCIENCE FOUNDATION | 2022-04-21 | — | — | US | disclosed |
| CN-114340680-A | Trans-cyclooctene bioorthogonal agents and uses in cancer and immunotherapy | 坦博公司 | 2022-04-12 | — | — | CN | disclosed |
| US-11281914-B2 | Vehicle monitoring system and vehicle monitoring method | PANASONIC I-PRO SENSING SOLUTIONS CO., LTD. (JP) | 2022-03-22 | — | — | US | disclosed |
| EP-3960729-A1 | COMPOUNDS AND METHODS OF TREATING INFECTIONS | Neoculi Pty Ltd (AU) | 2022-03-02 | — | — | EP | disclosed |
| WO-2022038536-A1 | METHODS OF INCREASING OUTCROSSING RATES IN GRAMINEAE | INTERNATIONAL RICE RESEARCH INSTITUTE (PH) | 2022-02-24 | — | — | WO | disclosed |
| US-11253600-B2 | Bioorthogonal compositions | TAMBO, INC. (US) | 2022-02-22 | — | — | US | disclosed |
| US-11230524-B2 | Myocyte enhancer factor 2 (MEF2) modulators | STANDARD LLC (US) | 2022-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11230524-B2 | Myocyte enhancer factor 2 (MEF2) modulators | MEF2D, MYLK2, TNNT2 | ADRA2A 789/4885ADRA2C 713/4885ADRA2B 583/4885 |
| US-20220119352-A1 | BIS-CYCLIC GUANIDINES AS ANTIBACTERIAL AGENTS | GMPS, CGAS, GDA | ADRA2A 1941/4885ADRA2C 1761/4885ADRA2B 1397/4885 |
| US-20260072513-A1 | Sensory Control Method, Sensory Control System, Method For Generating Conversion Model, Conversion Model Generation System, Method For Converting Relational Expression, And Program | TRRAP, PIEZO1, L1CAM | ADRA2A 1824/4885ADRA2C 1371/4885ADRA2B 2029/4885 |
| US-20260127545-A1 | SIMULATION MODEL GENERATION METHOD, SIMULATION MODEL GENERATION PROGRAM, AND SIMULATION MODEL GENERATION SYSTEM | ATP5PO, TIMM44, IPO11 | ADRA2A 2387/4885ADRA2C 2771/4885ADRA2B 3509/4885 |
| US-12611461-B2 | Bioorthogonal compositions | ACVRL1, FCGR2A, CHIT1 | ADRA2A 1930/4885ADRA2C 1387/4885ADRA2B 1383/4885 |
| US-12551959-B2 | Solder supply unit, solder piece manufacturing device, part mounting device, and production system | WAPL, CUTA, LANCL2 | ADRA2A 4516/4885ADRA2C 4811/4885ADRA2B 4622/4885 |
| US-11253600-B2 | Bioorthogonal compositions | TIE1, BBOX1, ST14 | ADRA2A 3331/4885ADRA2C 3196/4885ADRA2B 3477/4885 |
| US-20260079462-A1 | METHOD OF MANAGING MANUFACTURING LINE | MOK, THPO, MRPL9 | ADRA2A 3170/4885ADRA2C 4197/4885ADRA2B 3733/4885 |
| US-20260045791-A1 | ELECTRICAL LINE SELECTOR SYSTEM HAVING MULTIPLE SOURCES | MCU, SET, PC | ADRA2A 3229/4885ADRA2C 3053/4885ADRA2B 3860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.