SCHEMBL29757148

SCHEMBL29757148

CNCC(=O)c1cccc(O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.55
ALDH1A1 P00352 2/20 0.55
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA6 P23280 1/20 0.52
CA9 Q16790 1/20 0.52
EGLN2 Q96KS0 1/20 0.52
PARP1 P09874 1/20 0.50
GAA P10253 3/20 0.47
MAPT P10636 1/20 0.47
CTNNB1 P35222 1/20 0.45
FASN P49327 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
CLK1 P49759 1/20 0.43
DYRK1A Q13627 1/20 0.43
DYRK1B Q9Y463 1/20 0.43
FAAH O00519 1/20 0.43
RAB9A P51151 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1274658 1.00 KDM4E (0.55) KDM4EALDH1A1CA12CA1CA2
Hydrochloric Acid SCHEMBL4734485 0.98 KDM4E (0.53) KDM4EALDH1A1CA12CA1CA2
Hydrochloric Acid SCHEMBL31491126 0.98 KDM4E (0.53) KDM4EALDH1A1CA12CA1CA2
Sulfuric Acid SCHEMBL4016436 0.93 KDM4E (0.49) KDM4EALDH1A1CA12CA1CA2
SCHEMBL7446526 0.82 KDM4E (0.51) KDM4EALDH1A1CA12CA1CA2
SCHEMBL24229642 0.81 HDAC8 (0.55) KDM4EPARP1MAPTCTNNB1MEN1
Hydrochloric Acid SCHEMBL11756049 0.81 KDM4E (0.50) KDM4EALDH1A1CA12CA1CA2
SCHEMBL10481543 0.80 ERCC5 (0.60) KDM4EALDH1A1PARP1MAPTMEN1
SCHEMBL2292351 0.80 CES2 (0.55) KDM4EALDH1A1PARP1MAPTCTNNB1
SCHEMBL12656032 0.80 L3MBTL1 (0.54) KDM4EALDH1A1PARP1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220257537-A1 DILUTE READY TO USE LARGE VOLUME CONTAINERS OF PHENYLEPHRINE SINTETICA S.A. (CH) 2022-08-18 US claimed
WO-2022172253-A1 DILUTE READY TO USE LARGE VOLUME CONTAINERS OF PHENYLEPHRINE SINTETICA S.A. (CH) 2022-08-18 WO claimed
US-20260060942-A1 Phenylephrine Hydrochloride Compositions and Containers PH HEALTH LTD (IE) 2026-03-05 US disclosed
US-12564561-B2 Dilute ready to use large volume containers of phenylephrine SINTETICA S.A. (CH) 2026-03-03 US disclosed
US-12427123-B2 Phenylephrine hydrochloride compositions and containers ENDO OPERATIONS LIMITED (IE) 2025-09-30 US disclosed
CN-119751229-A Synthesis method of phenylephrine intermediate 3-hydroxy-2' -chloroacetophenone derivative 深圳格林凯特医药技术有限公司 2025-04-04 CN disclosed
US-20240366532-A1 PHENYLEPHRINE HYDROCHLORIDE COMPOSITIONS AND CONTAINERS WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT 2024-11-07 US disclosed
EP-4456886-A1 PHENYLEPHRINE PREMIX FORMULATIONS AND USES THEREOF BAXTER INTERNATIONAL INC. (US) 2024-11-06 EP disclosed
WO-2023129926-A1 PHENYLEPHRINE PREMIX FORMULATIONS AND USES THEREOF BAXTER INTERNATIONAL INC. (US) 2023-07-06 WO disclosed
US-20230201140-A1 PHENYLEPHRINE PREMIX FORMULATIONS AND USES THEREOF BAXTER PHARMACEUTICALS INDIA PRIVATE LIMITED (IN) 2023-06-29 US disclosed
US-20220257537-A1 DILUTE READY TO USE LARGE VOLUME CONTAINERS OF PHENYLEPHRINE SINTETICA S.A. (CH) 2022-08-18 US disclosed
WO-2022172253-A1 DILUTE READY TO USE LARGE VOLUME CONTAINERS OF PHENYLEPHRINE SINTETICA S.A. (CH) 2022-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230201140-A1 PHENYLEPHRINE PREMIX FORMULATIONS AND USES THEREOF PAH, PPOX, EPHX1 KDM4E 1493/4885ALDH1A1 2218/4885CA12 4484/4885
US-12427123-B2 Phenylephrine hydrochloride compositions and containers ADRA1A, ADRA2C, ADRB1 KDM4E 917/4885ALDH1A1 459/4885CA12 4347/4885
US-20260060942-A1 Phenylephrine Hydrochloride Compositions and Containers ADRA1D, ADRA2C, ADRB2 KDM4E 896/4885ALDH1A1 234/4885CA12 1506/4885
US-12564561-B2 Dilute ready to use large volume containers of phenylephrine GPX4, TNNC1, AGTR1 KDM4E 1339/4885ALDH1A1 1563/4885CA12 4616/4885
US-20240366532-A1 PHENYLEPHRINE HYDROCHLORIDE COMPOSITIONS AND CONTAINERS ADRA1A, ADRA2C, ADRB1 KDM4E 887/4885ALDH1A1 440/4885CA12 4374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.