SCHEMBL3008763

SCHEMBL3008763

CN1CCC(Nc2ccc(-c3cc4cc(Cl)cc(NC5CCCC5)c4[nH]3)cc2)CC1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.50
ITK Q08881 1/20 0.39
FLT3 P36888 14/20 0.39
NTRK3 Q16288 6/20 0.39
NTRK2 Q16620 6/20 0.39
NTRK1 P04629 5/20 0.39
ABL1 P00519 1/20 0.39
LCK P06239 1/20 0.39
CSF1R P07333 1/20 0.39
KIT P10721 1/20 0.39
BTK Q06187 1/20 0.39
IKBKB O14920 1/20 0.38
ERN1 O75460 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3009562 0.87 VCP (0.43) POLBIKBKBERN1
SCHEMBL3011458 0.83 CHEK1 (0.41) ABL1
SCHEMBL3013288 0.81 KIF11 (0.41) KIT
SCHEMBL3005194 0.81 ADORA1 (0.45) CSF1R
SCHEMBL3007638 0.80 ADORA1 (0.46) CSF1R
SCHEMBL2999191 0.78 HCAR3 (0.44)
SCHEMBL3007636 0.78 RIPK1 (0.40) POLBCSF1RKIT
SCHEMBL3748029 0.78 CHEK1 (0.39) KIT
SCHEMBL3013767 0.78 CHEK1 (0.41) CSF1R
SCHEMBL3723394 0.78 BCHE (0.44) ITK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250213583-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITION AND USE THEREOF MITOIMMUNE THERAPEUTICS INC. (KR) 2025-07-03 US claimed
US-20250082646-A1 OVARIAN ANTI-AGING PHARMACEUTICAL COMPOSITION AND USE THEREOF MITOIMMUNE THERAPEUTICS INC. (KR) 2025-03-13 US claimed
EP-4470541-A1 OVARIAN ANTI-AGING PHARMACEUTICAL COMPOSITION AND USE THEREOF MitoImmune Therapeutics Inc. (KR) 2024-12-04 EP claimed
US-20240374646-A1 COMPOSITION FOR INHIBITING INFLAMMATION OR AGING OF STEM CELLS, AND METHOD FOR INHIBITING INFLAMMATION OR AGING BY USING SAME MITOIMMUNE THERAPEUTICS INC. (KR) 2024-11-14 US claimed
WO-2024191106-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF EPILEPSY 주식회사 미토이뮨테라퓨틱스 2024-09-19 WO claimed
CN-118647383-A Anti-ovarian aging pharmaceutical composition and application thereof 水疗免疫疗法有限公司 2024-09-13 CN claimed
US-20240269145-A1 USE OF INDOLE COMPOUND AS INHIBITORS OF FERROPTOSIS MITOIMMUNE THERAPEUTICS INC. (KR) 2024-08-15 US claimed
EP-4382106-A1 COMPOSITION FOR INHIBITING INFLAMMATION OR AGING OF STEM CELLS, AND METHOD FOR INHIBITING INFLAMMATION OR AGING BY USING SAME MitoImmune Therapeutics Inc. (KR) 2024-06-12 EP claimed
WO-2023182840-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITION AND USE THEREOF 주식회사 미토이뮨테라퓨틱스 2023-09-28 WO claimed
WO-2023146341-A1 OVARIAN ANTI-AGING PHARMACEUTICAL COMPOSITION AND USE THEREOF 주식회사 미토이뮨테라퓨틱스 2023-08-03 WO claimed
WO-2022220517-A1 COMPOSITION FOR INHIBITING INFLAMMATION OR AGING OF STEM CELLS, AND METHOD FOR INHIBITING INFLAMMATION OR AGING BY USING SAME 주식회사 미토이뮨테라퓨틱스 2022-10-20 WO claimed
EP-2178870-B1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS LG CHEMICAL LTD (KR) 2018-09-19 EP claimed
US-20150038500-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING OPHTHALMIC DISORDERS CATHOLIC UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2015-02-05 US claimed
US-8436038-B2 Indole and indazole compounds as an inhibitor of cellular necrosis LG LIFE SCIENCES LTD. (KR) 2013-05-07 US claimed
US-20100197673-A1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS LG LIFE SCIENCES LTD (KR) 2010-08-05 US claimed
EP-2178870-A1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS LG Life Sciences Ltd. (KR) 2010-04-28 EP claimed
WO-2009025478-A1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS LG LIFE SCIENCES LTD. (KR) 2009-02-26 WO claimed
US-20250213583-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITION AND USE THEREOF MITOIMMUNE THERAPEUTICS INC. (KR) 2025-07-03 US disclosed
EP-2178870-A1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS LG Life Sciences Ltd. (KR) 2010-04-28 EP disclosed
WO-2009025478-A1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS LG LIFE SCIENCES LTD. (KR) 2009-02-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240374646-A1 COMPOSITION FOR INHIBITING INFLAMMATION OR AGING OF STEM CELLS, AND METHOD FOR INHIBITING INFLAMMATION OR AGING BY USING SAME TFAM, FIS1, AIFM1 POLB 1828/4885ITK 3089/4885FLT3 3972/4885
US-20250082646-A1 OVARIAN ANTI-AGING PHARMACEUTICAL COMPOSITION AND USE THEREOF CYP19A1, NR5A1, CYP11A1 POLB 1429/4885ITK 4329/4885FLT3 4845/4885
US-20250213583-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITION AND USE THEREOF ZC3HAV1, ZC3HAV1L, SARS1 POLB 819/4885ITK 2953/4885FLT3 3042/4885
US-20100197673-A1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS IDO1, IDO2, NFATC1 POLB 3982/4885ITK 1624/4885FLT3 3222/4885
US-20150038500-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING OPHTHALMIC DISORDERS AQP1, EYA3, SF1 POLB 3847/4885ITK 3391/4885FLT3 4727/4885
US-20240269145-A1 USE OF INDOLE COMPOUND AS INHIBITORS OF FERROPTOSIS AIFM2, FECH, SLC40A1 POLB 4821/4885ITK 4100/4885FLT3 3711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.