SCHEMBL306714

SCHEMBL306714

O=S(=O)([O-])CCOCCO.[Na+]

nearest known ligand 0.48

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB known ✓ P10828 1/20 0.32
TSHR P16473 4/20 0.48
MAPK1 P28482 2/20 0.48
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ALOX15 P16050 1/20 0.44
ALDH1A1 P00352 3/20 0.36
GMNN O75496 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
THPO P40225 1/20 0.36
HBB P68871 1/20 0.36
PMP22 Q01453 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ENPEP Q07075 2/20 0.34
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1356925 0.98 MEN1 (0.50) TSHRMAPK1MEN1KMT2AMAPT
SCHEMBL8380756 0.98 MEN1 (0.50) TSHRMAPK1MEN1KMT2AMAPT
SCHEMBL1356132 0.98 MEN1 (0.50) TSHRMAPK1MEN1KMT2AMAPT
SCHEMBL8532301 0.86 TSHR (0.43) TSHRMAPK1MEN1KMT2AMAPT
Di(Hydroxyethyl)Ether SCHEMBL15740534 0.85 TSHR (0.59) TSHRMAPK1MEN1KMT2AMAPT
Di(Hydroxyethyl)Ether SCHEMBL28142382 0.85 TSHR (0.59) TSHRMAPK1MEN1KMT2AMAPT
SCHEMBL27502688 0.85 MAPT (0.39) TSHRMAPK1MEN1KMT2AMAPT
SCHEMBL8529764 0.85 MEN1 (0.46) TSHRMAPK1MEN1KMT2AMAPT
Hexaethylene Glycol SCHEMBL11299109 0.82 MEN1 (0.61) TSHRMAPK1MEN1KMT2AMAPT
Di(Hydroxyethyl)Ether SCHEMBL28998971 0.80 TSHR (0.53) TSHRMAPK1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0765380-A1 DYE FADING PROTECTION FROM SOIL RELEASE AGENTS THE PROCTER & GAMBLE COMPANY (US) 1997-04-02 EP claimed
US-5486297-A COLORFASTNESS THE PROCTER & GAMBLE COMPANY (US) 1996-01-23 US claimed
WO-1995034626-A1 DYE FADING PROTECTION FROM SOIL RELEASE AGENTS THE PROCTER & GAMBLE COMPANY (US) 1995-12-21 WO claimed
US-12624158-B2 Polyesters comprising structural units with sulfonate groups, and polyalkoxy ether end groups, detergents, and cleaning agents comprising these and their use CATEXEL GMBH (DE) 2026-05-12 US disclosed
WO-2026087745-A1 AN ANTIOXIDANT COMPOSITION COMPRISING A CINNAMIC ACID DERIVATIVE BRAIN Biotech AG (DE) 2026-04-30 WO disclosed
EP-4732825-A1 AN ANTIOXIDANT COMPOSITION COMPRISING A CINNAMIC ACID DERIVATIVE BRAIN Biotech AG (DE) 2026-04-29 EP disclosed
EP-4025675-B1 A PERFUME OIL MIXTURE SYMRISE AG (DE) 2026-03-18 EP disclosed
US-20260071144-A1 DETERGENTS WITH IMPROVED DYE TRANSFER INHIBITION SYMRISE AG (DE) 2026-03-12 US disclosed
US-20260071145-A1 DETERGENTS AND CLEANING COMPOSITIONS WITH IMPROVED ANTI-REDEPOSITION PROPERTIES SYMRISE AG (DE) 2026-03-12 US disclosed
US-12534685-B2 Fragrance composition SYMRISE AG (DE) 2026-01-27 US disclosed
US-12503672-B2 Rim block with improved scent performance SYMRISE AG (DE) 2025-12-23 US disclosed
US-5415807-A Sulfonated poly-ethoxy/propoxy end-capped ester oligomers suitable as soil release agents in detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1995-05-16 US disclosed
US-5393466-A Mild surfactants LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1995-02-28 US disclosed
WO-1995002681-A1 DETERGENT-PACKAGE COMBINATION THE PROCTER & GAMBLE COMPANY (US) 1995-01-26 WO disclosed
WO-1995002029-A1 DETERGENT COMPOSITIONS COMPRISING SOIL RELEASE AGENTS THE PROCTER & GAMBLE COMPANY (US) 1995-01-19 WO disclosed
WO-1995002028-A1 DETERGENT COMPOSITIONS COMPRISING SOIL RELEASE AGENTS THE PROCTER & GAMBLE COMPANY (US) 1995-01-19 WO disclosed
WO-1995002030-A1 DETERGENT COMPOSITIONS COMPRISING SOIL RELEASE AGENTS THE PROCTER & GAMBLE COMPANY (US) 1995-01-19 WO disclosed
EP-0634485-A1 Detergent-package combination THE PROCTER & GAMBLE COMPANY (US) 1995-01-18 EP disclosed
WO-1994022937-A1 SULFONATED ESTER OLIGOMERS SUITABLE AS DISPERSING AGENTS IN DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1994-10-13 WO disclosed
EP-0544478-A1 Fatty acid esters of alkoxylated isethionic acid and detergent compositions comprising the same UNILEVER PLC (GB) 1993-06-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071144-A1 DETERGENTS WITH IMPROVED DYE TRANSFER INHIBITION HSD17B1, HSDL2, HSD17B3 THRB 2893/4885TSHR 4553/4885MAPK1 2584/4885
US-12534685-B2 Fragrance composition NCLN, HCN2, TRPA1 THRB 2618/4885TSHR 3358/4885MAPK1 2396/4885
US-20260071145-A1 DETERGENTS AND CLEANING COMPOSITIONS WITH IMPROVED ANTI-REDEPOSITION PROPERTIES CYP51A1, HSD17B1, HSD3B1 THRB 3436/4885TSHR 4564/4885MAPK1 2797/4885
US-12624158-B2 Polyesters comprising structural units with sulfonate groups, and polyalkoxy ether end groups, detergents, and cleaning agents comprising these and their use SIGMAR1, MSR1, CBR1 THRB 3263/4885TSHR 2333/4885MAPK1 3355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.