SCHEMBL3128644

SCHEMBL3128644

C[Si](C)(C)O[Si](C)(CCCNc1ncncn1)O[Si](C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30408140 0.77 ALDH1A1 (0.33) ALDH1A1HPGD
SCHEMBL689466 0.75 KMT2A (0.43) ALDH1A1
SCHEMBL29595323 0.75 ALDH1A1 (0.31) ALDH1A1HPGD
SCHEMBL29878588 0.74 ALDH1A1 (0.37) ALDH1A1HPGD
SCHEMBL4723163 0.74 HCAR3 (0.41) ALDH1A1
SCHEMBL21752802 0.73 KCNH3 (0.47) ALDH1A1
SCHEMBL514930 0.72 KCNH3 (0.46) ALDH1A1
SCHEMBL4147081 0.71 CYP1A2 (0.38) ALDH1A1
SCHEMBL28859626 0.71 DNM2 (0.46)
SCHEMBL6671613 0.71 DNM2 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3281620-B1 PHOTOPROTECTIVE COMPOSITION BASED ON A 2-ALKOXY-4-ALKYL KETONE PHENOL COMPOUND OREAL (FR) 2026-02-18 EP claimed
US-12102700-B2 Fluid photoprotective composition L'OREAL (FR) 2024-10-01 US claimed
EP-1484051-B1 Use of at least one blue-light screening agent to preserve the amount of endogenous carotenoids in the skin, new blue- light screening agents, cosmetic compositions. OREAL (FR) 2013-08-21 EP claimed
EP-4727518-A1 STABLE UV-SHELDING COMPOSITION L'OREAL (FR) 2026-04-22 EP disclosed
EP-4724153-A1 SUNSCREEN COMPOSITIONS AND METHODS OF USE Mary Kay, Inc. (US) 2026-04-15 EP disclosed
EP-3281620-B1 PHOTOPROTECTIVE COMPOSITION BASED ON A 2-ALKOXY-4-ALKYL KETONE PHENOL COMPOUND OREAL (FR) 2026-02-18 EP disclosed
US-20250235392-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND A GAMMA-BUTYROLACTONE AND/OR A GAMMA-BUTYROLACTAM L'OREAL (FR) 2025-07-24 US disclosed
US-12303581-B2 Cosmetic emulsion containing a gemini surfactant and a lipophilic polymer L'OREAL (FR) 2025-05-20 US disclosed
US-20250049674-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST A MEROCYANINE AND A HYDROTROPE L'OREAL (FR) 2025-02-13 US disclosed
US-20250025393-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND DIPROPYLENE GLYCOL L'OREAL (FR) 2025-01-23 US disclosed
US-20250017835-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND RESVERATROL AND/OR A RESVERATROL DERIVATIVE L'OREAL (FR) 2025-01-16 US disclosed
US-11458083-B2 Cosmetic and/or dermatological composition containing a merocyanine derivative comprising specific polar groups consisting of hydroxyl- and ether-functionalities L'OREAL (FR) 2022-10-04 US disclosed
WO-2022180010-A2 COMPOSITION COMPRISING AN ORGANIC UV-SCREENING AGENT, A SUPERABSORBANT POLYMER, PERLITE AND A FATTY ALCOHOL L'OREAL (FR) 2022-09-01 WO disclosed
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND L'OREAL (FR) 2022-07-21 US disclosed
US-11376205-B2 Water-in-oil emulsion containing baicalin, a xanthine base, a vitamin B3, and a polyvalent metal cation salt L'OREAL (FR) 2022-07-05 US disclosed
US-11344487-B2 Photoprotective compositions comprising a dibenzoylmethane derivative, a merocyanine compound and a compound capable of accepting the triplet excited level energy of the dibenzoylmethane compound L'OREAL (FR) 2022-05-31 US disclosed
EP-3407860-B1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE ISOSORBIDE ETHER OREAL (FR) 2022-03-16 EP disclosed
EP-2470158-B1 COMPOSITION CONTAINING AT LEAST ONE LIPOPHILIC 2-HYDROXYBENZOPHENONE FILTER AND A SILICON S-TRIAZINE SUBSTITUTED BY AT LEAST TWO ALKYLAMINOBENZOATE GROUPS ORÉAL L (FR) 2016-10-05 EP disclosed
EP-1484051-B1 Use of at least one blue-light screening agent to preserve the amount of endogenous carotenoids in the skin, new blue- light screening agents, cosmetic compositions. OREAL (FR) 2013-08-21 EP disclosed
EP-2193782-A1 Cosmetic composition comprising a dibenzoylmethane derivative and a 2-pyrrolidinone-4-carboxy ester compound; method for the photostabilization of the dibenzoylmethane derivative L'Oreal (FR) 2010-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11458083-B2 Cosmetic and/or dermatological composition containing a merocyanine derivative comprising specific polar groups consisting of hydroxyl- and ether-functionalities KRT18, LAGE3, TYR ALDH1A1 1018/4885HPGD 791/4885
US-11376205-B2 Water-in-oil emulsion containing baicalin, a xanthine base, a vitamin B3, and a polyvalent metal cation salt KRT18, BROX, S100B ALDH1A1 4247/4885HPGD 772/4885
US-20250017835-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND RESVERATROL AND/OR A RESVERATROL DERIVATIVE KRT18, ECH1, VIM ALDH1A1 2200/4885HPGD 3034/4885
US-20250235392-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND A GAMMA-BUTYROLACTONE AND/OR A GAMMA-BUTYROLACTAM KRT18, YWHAZ, BTN3A1 ALDH1A1 756/4885HPGD 1723/4885
US-11344487-B2 Photoprotective compositions comprising a dibenzoylmethane derivative, a merocyanine compound and a compound capable of accepting the triplet excited level energy of the dibenzoylmethane compound DDT, ERCC5, ERCC1 ALDH1A1 864/4885HPGD 1789/4885
US-20250049674-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST A MEROCYANINE AND A HYDROTROPE NAPRT, NAMPT, NNMT ALDH1A1 745/4885HPGD 8/4885
US-20250025393-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND DIPROPYLENE GLYCOL KRT18, DSC1, DSG1 ALDH1A1 2036/4885HPGD 1866/4885
US-12303581-B2 Cosmetic emulsion containing a gemini surfactant and a lipophilic polymer GMNN, MGLL, DGKI ALDH1A1 4004/4885HPGD 2826/4885
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND ERCC5, DDT, ERCC1 ALDH1A1 815/4885HPGD 1859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.