SCHEMBL346645

SCHEMBL346645

c1ccc(Cc2nc(-c3cc(-c4cn(-c5ccccc5)c(Cc5ccccc5)n4)cc(-c4cn(-c5ccccc5)c(Cc5ccccc5)n4)c3)cn2-c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ALDH1A1 P00352 4/20 0.39
HPGD P15428 1/20 0.39
RXFP1 Q9HBX9 1/20 0.38
LMNA P02545 1/20 0.36
MAPT P10636 2/20 0.36
TP53 P04637 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
POLB P06746 1/20 0.35
ADCY10 Q96PN6 1/20 0.35
ABCB1 P08183 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18492714 0.92 MAPT (0.42) NPC1RAB9AALDH1A1HPGDRXFP1
SCHEMBL10666225 0.79 ALDH1A3 (0.47) NPC1RAB9A
Hydrochloric Acid SCHEMBL10667738 0.76 WDR5 (0.42)
SCHEMBL755602 0.74 GABRA2 (0.40) RAB9AALDH1A1SMN1; SMN2
SCHEMBL9715787 0.69 GABRA2 (0.47)
SCHEMBL4447659 0.66 MAPT (0.41) NPC1RAB9AALDH1A1LMNAMAPT
Benzene SCHEMBL20549155 0.66 L3MBTL1 (0.53) NPC1RAB9AALDH1A1HPGDLMNA
SCHEMBL28173706 0.66 L3MBTL1 (0.53) NPC1RAB9AALDH1A1HPGDLMNA
SCHEMBL82549 0.65 PTGS1 (0.62) NPC1RAB9AALDH1A1HPGDLMNA
SCHEMBL5345839 0.63 MAPT (0.61) NPC1RAB9AALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622170-B2 Fluorescent organic light emitting elements having high efficiency UDC Ireland (IE) 2026-05-05 US disclosed
US-12538704-B2 4H-imidazo[1,2-a]imidazoles for electronic applications UDC IRELAND LIMITED (IE) 2026-01-27 US disclosed
CN-107814821-B Metal complexes with dibenzo [ F, H ] quinoxalines UDC 爱尔兰有限责任公司 2025-03-07 CN disclosed
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2023-11-23 US disclosed
US-11744152-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency UDC IRELAND LIMITED (IE) 2023-07-18 US disclosed
US-20230090208-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications UDC IRELAND LTD (IE) 2023-03-23 US disclosed
US-11450812-B2 4H-imidazo[1,2-a]imidazoles for electronic applications UDC IRELAND LIMITED (IE) 2022-09-20 US disclosed
CN-108699058-B Hetero-fused phenylquinazolines and their use in electronic devices 出光兴产株式会社 2022-07-08 CN disclosed
EP-3356369-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING TRIAZINE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2022-05-04 EP disclosed
US-8362246-B2 Bispyrimidines for electronic applications BASF SE (DE) 2013-01-29 US disclosed
US-20120241681-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications BASF SE (DE) 2012-09-27 US disclosed
US-8241764-B2 OLED display with extended lifetime BASF AKTIENGESELLSCHAFT (DE) 2012-08-14 US disclosed
US-20120149904-A1 BISPYRIMIDINES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2012-06-14 US disclosed
US-20120095222-A1 PHENANTHRO[9, 10-B]FURANS FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2012-04-19 US disclosed
US-20120012821-A1 SILYL- AND HETEROATOM-SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZOPHOSPHOLES, AND USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2012-01-19 US disclosed
US-20110309346-A1 ORGANIC ELECTRONIC DEVICES COMPRISING A LAYER COMPRISING AT LEAST ONE METAL ORGANIC COMPOUND AND AT LEAST ONE METAL OXIDE BASF SE (DE) 2011-12-22 US disclosed
US-20110266528-A1 SUBSTITUTED CARBAZOLE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2011-11-03 US disclosed
US-20110198578-A1 SILOLES SUBSTITUTED BY FUSED RING SYSTEMS AND USE THEREOF IN ORGANIC ELECTRONICS OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2011-08-18 US disclosed
US-20090278119-A1 OLED DISPLAY WITH EXTENDED LIFETIME BASF SE (DE) 2009-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11450812-B2 4H-imidazo[1,2-a]imidazoles for electronic applications PAH, NISCH, KCNH1 NPC1 3851/4885RAB9A 447/4885ALDH1A1 405/4885
US-20120241681-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications EIF4A1, ITPR2, ITPR1 NPC1 4473/4885RAB9A 764/4885ALDH1A1 355/4885
US-20120149904-A1 BISPYRIMIDINES FOR ELECTRONIC APPLICATIONS DPYD, TYMP, TYMS NPC1 4490/4885RAB9A 2237/4885ALDH1A1 717/4885
US-12622170-B2 Fluorescent organic light emitting elements having high efficiency TEAD1, EEF1D, TEAD2 NPC1 2337/4885RAB9A 438/4885ALDH1A1 366/4885
US-20110198578-A1 SILOLES SUBSTITUTED BY FUSED RING SYSTEMS AND USE THEREOF IN ORGANIC ELECTRONICS HLCS, LAGE3, SUMO3 NPC1 3771/4885RAB9A 2126/4885ALDH1A1 1138/4885
US-12538704-B2 4H-imidazo[1,2-a]imidazoles for electronic applications RIF1, NR2E1, NR3C1 NPC1 3180/4885RAB9A 925/4885ALDH1A1 680/4885
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 NPC1 2870/4885RAB9A 1728/4885ALDH1A1 380/4885
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency TEAD1, TEAD2, TEAD4 NPC1 2870/4885RAB9A 1728/4885ALDH1A1 380/4885
US-20230090208-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications PAH, NISCH, KCNH1 NPC1 3851/4885RAB9A 447/4885ALDH1A1 405/4885
US-20120095222-A1 PHENANTHRO[9, 10-B]FURANS FOR ELECTRONIC APPLICATIONS P2RY10, P2RY11, P2RY12 NPC1 4451/4885RAB9A 318/4885ALDH1A1 1910/4885
US-11744152-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications PAICS, EIF4A1, ECI1 NPC1 4384/4885RAB9A 1588/4885ALDH1A1 122/4885
US-20110266528-A1 SUBSTITUTED CARBAZOLE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTRONICS NR2E3, CHRNA5, CHRNA4 NPC1 4492/4885RAB9A 4001/4885ALDH1A1 2923/4885
US-20120012821-A1 SILYL- AND HETEROATOM-SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZOPHOSPHOLES, AND USE THEREOF IN ORGANIC ELECTRONICS DDT, CDKL1, CDK2 NPC1 4516/4885RAB9A 3555/4885ALDH1A1 750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.