SCHEMBL4394738

SCHEMBL4394738

N[C@@H](CCSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 19/20 0.61
DNMT1 P26358 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4469967 1.00 KIF11 (0.61) KIF11DNMT1
SCHEMBL4462064 1.00 KIF11 (0.61) KIF11DNMT1
SCHEMBL27164908 0.90 KIF11 (0.58) KIF11DNMT1
SCHEMBL27204495 0.90 KIF11 (0.58) KIF11DNMT1
SCHEMBL29855499 0.89 KIF11 (0.54) KIF11DNMT1
SCHEMBL8537950 0.89 KIF11 (0.54) KIF11DNMT1
SCHEMBL28325722 0.88 KIF11 (0.77) KIF11DNMT1
SCHEMBL28325721 0.88 KIF11 (0.77) KIF11DNMT1
S-Trityl-L-Cysteine SCHEMBL768202 0.83 KIF11 (0.85) KIF11DNMT1
S-Trityl-L-Cysteine SCHEMBL768203 0.83 KIF11 (0.85) KIF11DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 US claimed
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2023-04-13 US claimed
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-11-24 US claimed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US disclosed
US-20260098247-A1 DEVELOPMENT OF SOLID-STATE STORAGE OF COMPLEX BIOCHEMICAL SYSTEMS CAL POLY CORP (US) 2026-04-09 US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 US disclosed
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-03-12 US disclosed
US-20260069175-A1 SAMPLE-TO-ANSWER DIAGNOSTIC SYSTEM FOR THE DETECTION OF CIRCULATING HISTONES IN WHOLE BLOOD UNIV MARYLAND (US) 2026-03-12 US disclosed
US-12551149-B2 Sample-to-answer diagnostic system for the detection of circulating histones in whole blood UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2026-02-17 US disclosed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 US disclosed
US-5985241-A DIAGNOSTIC AND RADIODIAGNOSTIC AGENTS, FORMED BY REACTING TECHNETIUM-99M WITH A SOMATOSTATIN RECEPTOR-BINDING PEPTIDE DIATIDE, INC. (US) 1999-11-16 US disclosed
US-5981477-A ADMINISTERING TO THE MAMMAL BEARING SOMATOSTATIN RECEPTOR EXPRESSING TUMOR, A METAL ION COMPLEXED SOMATOSTATIN RECEPTOR BINDING CYCLIC PEPTIDE DIATIDE, INC. (US) 1999-11-09 US disclosed
US-5972308-A REACTING TECHNETIUM-99 WITH A CYCLIC OLIGOPEPTIDE HAVING AMINO ACID UNITS CONTAINING A MERCAPTAN GROUP ATTACHED TO THE RING THROUGH A HOMOCYSTEINE UNIT. DIATIDE, INC. (US) 1999-10-26 US disclosed
US-5965108-A CYCLIC PEPTIDE-METAL COMPLEX SPECIFICALLY BINDS TO SURFACE SOMATOSTATIN RECEPTOR-EXPRESSING CELLS; RADIOLOGY; SCINTIGRAPHY; ANTITUMOR,-CARCINOGENIC AND METASTATIC AGENTS; STABILITY DIATIDE, INC. (US) 1999-10-12 US disclosed
US-5783170-A Peptide-metal chelate conjugates DIATIDE, INC. (US) 1998-07-21 US disclosed
CN-1155248-A Somatostatin binding peptide-metal chelate conjugates DIATECH INC (US) 1997-07-23 CN disclosed
US-4560795-A α-Halomethyl derivatives of α-amino acids Merrell Dow France et Cie. (FR) 1985-12-24 US disclosed
US-4438270-A DECARBOXYLASE INHIBITORS MERRELL TORAUDE ET COMPAGNIE (FR) 1984-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351573-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM KIF11 2096/4885DNMT1 1421/4885
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS KIF11 4280/4885DNMT1 564/4885
US-20260069175-A1 SAMPLE-TO-ANSWER DIAGNOSTIC SYSTEM FOR THE DETECTION OF CIRCULATING HISTONES IN WHOLE BLOOD H1-3, H1-2, H1-4 KIF11 2312/4885DNMT1 127/4885
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS NPR1, NGLY1, DDAH1 KIF11 4306/4885DNMT1 3720/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 KIF11 4534/4885DNMT1 938/4885
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC KIF11 2900/4885DNMT1 1003/4885
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS DNPEP, NPEPPS, PAM KIF11 2096/4885DNMT1 1421/4885
US-12551149-B2 Sample-to-answer diagnostic system for the detection of circulating histones in whole blood H1-3, H1-2, H1-4 KIF11 2241/4885DNMT1 181/4885
US-20260098247-A1 DEVELOPMENT OF SOLID-STATE STORAGE OF COMPLEX BIOCHEMICAL SYSTEMS CS, CD44, PSAT1 KIF11 1165/4885DNMT1 4218/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT KIF11 4615/4885DNMT1 1907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.