SCHEMBL4408352

SCHEMBL4408352

Cc1nnn(CC(C)(C)C)n1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18021885 0.83 ALDH1A1 (0.31)
SCHEMBL4408001 0.76 CNR1 (0.32) CNR1CNR2
SCHEMBL4407475 0.76 CNR1 (0.32) CNR1CNR2
SCHEMBL4412009 0.74 PKM (0.34) CNR1CNR2
SCHEMBL4413432 0.74 CNR1 (0.32) CNR1CNR2
SCHEMBL4408285 0.72 SLC6A2 (0.31) CNR1CNR2
SCHEMBL4414548 0.72 ALDH1A1 (0.32) CNR1CNR2
SCHEMBL4405551 0.72 CNR1 (0.31) CNR1CNR2
SCHEMBL4407947 0.71 PKM (0.33) CNR1CNR2
SCHEMBL4404340 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814367-B2 Inhibitors of glycogen synthase 1 (GYS1) and methods of use thereof MAZE THERAPEUTICS, INC. (US) 2023-11-14 US disclosed
US-11814367-B2 Inhibitors of glycogen synthase 1 (GYS1) and methods of use thereof MAZE THERAPEUTICS, INC. (US) 2023-11-14 US disclosed
US-20230339844-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2023-10-26 US disclosed
US-20230339844-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2023-10-26 US disclosed
US-11718584-B2 Process for the synthesis anthranilic diamide compounds and intermediates thereof PI INDUSTRIES LTD. (IN) 2023-08-08 US disclosed
US-20220144814-A1 A PROCESS FOR PREPARING ANTHRANILIC DIAMIDES AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2022-05-12 US disclosed
US-11312713-B2 Imidazo[4,5-C]quinoline derivatives as LRRK2 inhibitors PFIZER INC. (US) 2022-04-26 US disclosed
US-20210355117-A1 NOVEL IMIDAZO[4,5-C]QUINOLINE DERIVATIVES AS LRRK2 INHIBITORS PFIZER (US) 2021-11-18 US disclosed
EP-1859782-B1 Composition for coloring and/or lightening human hair comprising tetrazoles HENKEL AG & CO KGAA (DE) 2009-12-30 EP disclosed
EP-1859782-A1 Composition for coloring and/or lightening human hair comprising tetrazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718584-B2 Process for the synthesis anthranilic diamide compounds and intermediates thereof DAO, DDC, QDPR CNR1 3202/4885CNR2 2351/4885
US-11814367-B2 Inhibitors of glycogen synthase 1 (GYS1) and methods of use thereof GYS2, GYS1, PYGL CNR1 4000/4885CNR2 4603/4885
US-11312713-B2 Imidazo[4,5-C]quinoline derivatives as LRRK2 inhibitors LRRK2, PARK7, BRCA1 CNR1 2094/4885CNR2 2304/4885
US-20220144814-A1 A PROCESS FOR PREPARING ANTHRANILIC DIAMIDES AND INTERMEDIATES THEREOF F12, IDH3B, CA7 CNR1 755/4885CNR2 660/4885
US-20230339844-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF ASS1, ACMSD, ADCY10 CNR1 1450/4885CNR2 1556/4885
US-20210355117-A1 NOVEL IMIDAZO[4,5-C]QUINOLINE DERIVATIVES AS LRRK2 INHIBITORS LRRK2, PARK7, BRCA1 CNR1 2175/4885CNR2 2467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.