SCHEMBL4439360

SCHEMBL4439360

CC(CCc1ccccc1)CC(=O)O

nearest known ligand 0.81

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.54
MMP12 P39900 3/20 0.53
MMP2 P08253 1/20 0.53
MMP9 P14780 1/20 0.53
MMP13 P45452 1/20 0.53
MMP14 P50281 1/20 0.53
MEN1 O00255 1/20 0.51
HTT P42858 1/20 0.51
KMT2A Q03164 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
HPGD P15428 1/20 0.51
CYSLTR2 Q9NS75 1/20 0.50
CYSLTR1 Q9Y271 1/20 0.50
KEAP1 Q14145 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2478370 1.00 TSHR (0.54) TSHRMMP12MMP2MMP9MMP13
SCHEMBL26837610 1.00 TSHR (0.54) TSHRMMP12MMP2MMP9MMP13
Nitrous Acid SCHEMBL26607946 0.93 TSHR (0.49) TSHRMMP12MMP2MMP9MMP13
SCHEMBL11875805 0.90 MMP12 (0.69) TSHRMMP12MMP2MMP9MMP13
SCHEMBL5074784 0.86 MAPT (0.56) KMT2ASMN1; SMN2HPGD
SCHEMBL14016007 0.86 MAPT (0.56) KMT2ASMN1; SMN2HPGD
SCHEMBL661213 0.85 TSHR (0.51) TSHRMEN1HTTKMT2ASMN1; SMN2
SCHEMBL25954987 0.85 FFAR1 (0.47) MMP12MMP2MMP9MMP13MMP14
SCHEMBL11578170 0.85 ALDH1A1 (0.53) TSHRMMP12MMP2MMP9MMP13
SCHEMBL7621975 0.84 GAA (0.45) MMP12MMP2MMP9MMP13MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6844302-B1 Encapsulated flavor and fragrance INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2005-01-18 US claimed
US-12630781-B2 Fragrance or flavour mixture SYMRISE AG (DE) 2026-05-19 US disclosed
US-12630783-B2 Muguet type fragrance compounds SYMRISE AG (DE) 2026-05-19 US disclosed
US-12625123-B2 Device and method for the analytical and sensory determination of the release of an active substance from a release system SYMRISE AG (DE) 2026-05-12 US disclosed
EP-4192614-B1 PROCESS FOR THE PREPARATION OF MICROCAPSULES SYMRISE AG (DE) 2026-05-06 EP disclosed
EP-4724434-A1 AMBERGRIS ISOMERS AND MIXTURES THEREOF Symrise AG (DE) 2026-04-15 EP disclosed
US-12583833-B2 Enrichment of a diastereomer in Magnolan SYMRISE AG (DE) 2026-03-24 US disclosed
US-12577495-B2 Fragrance mixtures containing 1-(4,4-dimethylcyclohexen-1-yl) ethanon SYMRISE AG (DE) 2026-03-17 US disclosed
US-12552732-B2 Cyclopropanated sandalwood type compounds SYMRISE AG (DE) 2026-02-17 US disclosed
EP-4687810-A1 PREPARATIONS COMPRISING HYDROXY PINACOLONE RETINOATE Symrise AG (DE) 2026-02-11 EP disclosed
US-7534908-B2 Method for the production of optically active 3-alkylcarboxylic acids and the intermediate products thereof WACKER CHEMIE AG (DE) 2009-05-19 US disclosed
US-20070225519-A1 Method for the Production of Optically Active 3-Alkyl Carboxylic Acids and the Intermediate Products Thereof CONSORTIUM FUER ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 2007-09-27 US disclosed
EP-1537174-A1 CYCLODEXTRIN PARTICLE Symrise GmbH & Co. KG (DE) 2005-06-08 EP disclosed
US-6844302-B1 Encapsulated flavor and fragrance INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2005-01-18 US disclosed
WO-2004022642-A1 CYCLODEXTRIN PARTICLE SYMRISE GMBH & CO. KG (DE) 2004-03-18 WO disclosed
WO-2004002930-A1 ODORIFEROUS SUBSTANCES AND METHOD FOR THE PRODUCTION THEREOF SYMRISE GMBH & CO. KG (DE) 2004-01-08 WO disclosed
US-6369110-B1 PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM SUMITOMO PHARMACEUTICALS COMPANY (JP) 2002-04-09 US disclosed
EP-1083166-A1 NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2001-03-14 EP disclosed
EP-0315071-B1 Benzocyclohepten derivatives, their preparation and utilisation for pharmaceutics HOFFMANN LA ROCHE (CH) 1994-07-20 EP disclosed
US-4992574-A Skin disorders, antiallergens, antiinflammatory agent HOFFMANN-LA ROCHE INC. (US) 1991-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583833-B2 Enrichment of a diastereomer in Magnolan TRPA1, ENO1, ADH1A TSHR 1897/4885MMP12 3775/4885MMP2 4308/4885
US-12577495-B2 Fragrance mixtures containing 1-(4,4-dimethylcyclohexen-1-yl) ethanon ALG3, FAAH, FAAH2 TSHR 4433/4885MMP12 4519/4885MMP2 4825/4885
US-12630783-B2 Muguet type fragrance compounds MGAT1, RFT1, CPT1A TSHR 4543/4885MMP12 4661/4885MMP2 3720/4885
US-12625123-B2 Device and method for the analytical and sensory determination of the release of an active substance from a release system TAS2R7, TAS2R42, TAS2R39 TSHR 1280/4885MMP12 3099/4885MMP2 959/4885
US-12552732-B2 Cyclopropanated sandalwood type compounds FAAH2, ADCY10, OR10J3 TSHR 4658/4885MMP12 4445/4885MMP2 4202/4885
US-12630781-B2 Fragrance or flavour mixture NOTUM, FFAR2, FFAR1 TSHR 1719/4885MMP12 3125/4885MMP2 3662/4885
US-20070225519-A1 Method for the Production of Optically Active 3-Alkyl Carboxylic Acids and the Intermediate Products Thereof ME1, ME3, ACMSD TSHR 2274/4885MMP12 1376/4885MMP2 1186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.