Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HMGCR | P04035 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.38 |
| ▸ | GLRB | P48167 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6056065 | 0.92 | CA2 (0.42) | LMNARECQLGAAHMGCRKMT2A | |
| SCHEMBL28115084 | 0.91 | ESR1 (0.44) | LMNARECQLGAAKMT2AGPR55 | |
| SCHEMBL28781425 | 0.90 | ESR1 (0.43) | LMNARECQLGAANR5A2NR5A1 | |
| SCHEMBL284356 | 0.89 | ESR1 (0.46) | LMNAALDH1A1NR5A2NR5A1 | |
| SCHEMBL20942816 | 0.89 | ESR1 (0.46) | LMNAALDH1A1NR5A2NR5A1 | |
| SCHEMBL25273215 | 0.89 | ESR1 (0.46) | LMNAALDH1A1NR5A2NR5A1 | |
| SCHEMBL11801616 | 0.89 | ESR1 (0.46) | LMNAALDH1A1NR5A2NR5A1 | |
| SCHEMBL22229452 | 0.89 | ESR1 (0.46) | LMNAALDH1A1NR5A2NR5A1 | |
| SCHEMBL283874 | 0.89 | ESR1 (0.46) | LMNAALDH1A1NR5A2NR5A1 | |
| SCHEMBL283852 | 0.89 | ESR1 (0.46) | LMNAALDH1A1NR5A2NR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120328541-A1 | Anti-radical agents | BASCHONG WERNER (CH) | 2012-12-27 | — | — | US | disclosed |
| EP-2197998-B1 | PERSONAL CARE COMPOSITIONS COMPRISING DYE-POLYMER COMPLEXES | BASF SE (DE) | 2012-12-26 | — | — | EP | disclosed |
| US-8216596-B2 | 4-Hydroxy-1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethylpiperidine, citric acid and a body care product; hindered amine salt compounds provide outstanding protection against light-induced fading | BASF SE (DE) | 2012-07-10 | — | — | US | disclosed |
| US-20120164162-A1 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BASF SE (DE) | 2012-06-28 | — | — | US | disclosed |
| US-20120129995-A1 | ENCAPSULATED PHENOLIC ANTIOXIDANTS | BASF SE (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20120121524-A1 | PHOTO-STABLE COSMETIC OR DERMATOLOGICAL COMPOSITIONS | MUELLER STEFAN (DE) | 2012-05-17 | — | — | US | disclosed |
| US-8119107-B2 | Photo-stable cosmetic or dermatological compositions | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8093320-B2 | Compositions comprising polyphosphonates and additives that exhibit an advantageous combination of properties, and methods related thereto | FRX POLYMERS, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| WO-2011012631-A1 | ENCAPSULATED PHENOLIC ANTIOXIDANTS | BASF SE (DE) | 2011-02-03 | — | — | WO | disclosed |
| US-20100204354-A1 | COMPOSITIONS COMPRISING POLYPHOSPHONATES AND ADDITIVES THAT EXHIBIT AN ADVANTAGEOUS COMBINATION OF PROPERTIES, AND METHODS RELATED THERETO | FRX POLYMERS, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| US-20090258041-A1 | Protection of Oxidizable Agents | CIBA CORP. | 2009-10-15 | — | — | US | disclosed |
| US-7589035-B2 | Stabilized body care products, household products, textiles and fabrics | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-09-15 | — | — | US | disclosed |
| US-20090214447-A1 | Preparation of cationic nanoparticles and personal care compositions comprising said nanoparticles | BASF SE (DE) | 2009-08-27 | — | — | US | disclosed |
| US-20090205144-A1 | Stabilized body care products, household products, textiles and fabrics | LUPIA JOSEPH A | 2009-08-20 | — | — | US | disclosed |
| US-20080305055-A1 | Anti-Radical Agents | CIBA CORPORATION | 2008-12-11 | — | — | US | disclosed |
| US-20080279794-A1 | Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin | BASCHONG WERNER | 2008-11-13 | — | — | US | disclosed |
| US-20080253981-A1 | Stabilized body care products, household products, textiles and fabrics | LUPIA JOSEPH A | 2008-10-16 | — | — | US | disclosed |
| US-7425320-B2 | Use of guaiol for treating the skin | CIBA SPECIALTY CHEMICALS CORP (US) | 2008-09-16 | — | — | US | disclosed |
| US-7410940-B2 | Antioxidants for the stabilization of surfactant formulations | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-08-12 | — | — | US | disclosed |
| US-20080108540-A1 | Antioxidants for the stabilization of formulations comprising surfactants | HUEGLIN DIETMAR | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120121524-A1 | PHOTO-STABLE COSMETIC OR DERMATOLOGICAL COMPOSITIONS | NISCH, CUTA, MITF | LMNA 1453/4885RECQL 1031/4885PTGS1 2480/4885 |
| US-20120328541-A1 | Anti-radical agents | NOS3, GSTO1, TXN2 | LMNA 1272/4885RECQL 1053/4885PTGS1 6/4885 |
| US-20080253981-A1 | Stabilized body care products, household products, textiles and fabrics | DSC1, CUTA, DSG1 | LMNA 1931/4885RECQL 1506/4885PTGS1 4720/4885 |
| US-20080305055-A1 | Anti-Radical Agents | NOS3, GSTO1, PTGS1 | LMNA 1686/4885RECQL 1058/4885PTGS1 3/4885 |
| US-20090214447-A1 | Preparation of cationic nanoparticles and personal care compositions comprising said nanoparticles | CUTA, ARG1, ARG2 | LMNA 1156/4885RECQL 3226/4885PTGS1 4148/4885 |
| US-20120164162-A1 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BBOX1, NEFM, NQO1 | LMNA 2498/4885RECQL 1892/4885PTGS1 554/4885 |
| US-20090258041-A1 | Protection of Oxidizable Agents | LPO, TYR, HAO2 | LMNA 1588/4885RECQL 1039/4885PTGS1 923/4885 |
| US-20080279794-A1 | Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin | MC1R, TYR, MC3R | LMNA 1651/4885RECQL 2138/4885PTGS1 1830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.