Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31281283 | 1.00 | PGR (0.52) | PGRMEN1ALDH1A1KMT2AADORA3 | |
| Bicarbonate SCHEMBL12613772 | 0.92 | ADORA3 (0.53) | PGRMEN1ALDH1A1KMT2AADORA3 | |
| SCHEMBL10051059 | 0.83 | CA1 (0.55) | ALDH1A1 | |
| SCHEMBL23208318 | 0.81 | PGR (0.46) | PGRMEN1ALDH1A1KMT2AMMP2 | |
| SCHEMBL31435391 | 0.81 | AKR1B1 (0.56) | PGRMEN1ALDH1A1KMT2AMMP2 | |
| SCHEMBL2199161 | 0.81 | AKR1B1 (0.56) | PGRMEN1ALDH1A1KMT2AMMP2 | |
| SCHEMBL294450 | 0.79 | PGR (0.53) | PGRMEN1ALDH1A1KMT2AMMP2 | |
| SCHEMBL8477676 | 0.79 | ALDH1A1 (0.59) | PGRMEN1ALDH1A1KMT2AMMP2 | |
| SCHEMBL29422524 | 0.79 | ALDH1A1 (0.54) | PGRMEN1ALDH1A1KMT2AMMP2 | |
| SCHEMBL294451 | 0.79 | ALDH1A1 (0.59) | PGRMEN1ALDH1A1KMT2AMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106866507-A | A kind of synthetic method for tieing up not Buddhist nun | 武汉博诚恒瑞医药科技有限公司 | 2017-06-20 | — | — | CN | claimed |
| EP-3632892-B1 | METHOD FOR PRODUCING 3-ARYLPROPIONAMIDE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2024-07-31 | — | — | EP | disclosed |
| US-20240092780-A1 | ADDUCTS AND DIMER COMPOUNDS SYNTHESIZED USING GK METHOD | ANKH LIFE SCIENCES LIMITED (IE) | 2024-03-21 | — | — | US | disclosed |
| WO-2023214412-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF PRIDOPIDINE | PRILENIA NEUROTHERAPEUTICS LTD. (IL) | 2023-11-09 | — | — | WO | disclosed |
| US-20230339878-A1 | SLC26A3 INHIBITORS AND USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-26 | — | — | US | disclosed |
| US-20230339878-A1 | SLC26A3 INHIBITORS AND USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-26 | — | — | US | disclosed |
| CN-110799490-B | 3-arylpropionamide compound and method for producing 3-arylpropionate compound | 住友化学株式会社 | 2023-05-02 | — | — | CN | disclosed |
| CN-114805050-A | Preparation method of C-H bond carboxylation of aromatic hydrocarbon containing halogen | 江苏百康德医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |
| US-11028056-B2 | Method for producing 3-arylpropionamide compound and 3-arylpropionic acid ester compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-06-08 | — | — | US | disclosed |
| US-20200165209-A1 | METHOD FOR PRODUCING 3-ARYLPROPIONAMIDE COMPOUND AND 3-ARYLPROPIONIC ACID ESTER COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-05-28 | — | — | US | disclosed |
| US-20070060569-A1 | Azacycloalkyl substituted acetic acid derivatives for use as MMP inhibitors | NOVARTIS AG (CH) | 2007-03-15 | — | — | US | disclosed |
| US-20070060569-A1 | Azacycloalkyl substituted acetic acid derivatives for use as MMP inhibitors | NOVARTIS AG (CH) | 2007-03-15 | — | — | US | disclosed |
| US-20070060754-A1 | Alkoxy substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY | 2007-03-15 | — | — | US | disclosed |
| US-20070060754-A1 | Alkoxy substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY | 2007-03-15 | — | — | US | disclosed |
| EP-1187811-B1 | INHIBITORS OF METALLOPROTEINASES | ASTRAZENECA AB (SE) | 2007-03-07 | — | — | EP | disclosed |
| US-20070049570-A1 | Quinoline derivatives as phosphodiesterase inhibitors | DEAN ANTHONY W | 2007-03-01 | — | — | US | disclosed |
| US-20070049570-A1 | Quinoline derivatives as phosphodiesterase inhibitors | DEAN ANTHONY W | 2007-03-01 | — | — | US | disclosed |
| WO-2004103998-A1 | QUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-02 | — | — | WO | disclosed |
| EP-1094810-A1 | USE OF PRENYLTRANSFERASE INHIBITORS FOR PREPARING A MEDICINE FOR TREATING PATHOLOGIES RESULTING FROM HETEROTRIMERIC G PROTEIN MEMBRANE FIXATION | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000002558-A1 | USE OF PRENYLTRANSFERASE INHIBITORS FOR PREPARING A MEDICINE FOR TREATING PATHOLOGIES RESULTING FROM HETEROTRIMERIC G PROTEIN MEMBRANE FIXATION | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339878-A1 | SLC26A3 INHIBITORS AND USE THEREOF | SLC26A3, SLC10A2, SLC10A6 | PGR 4458/4885MEN1 4700/4885ALDH1A1 2345/4885 |
| US-20070060754-A1 | Alkoxy substituted imidazoquinolines | IL2, IFNG, IRF3 | PGR 3227/4885MEN1 3720/4885ALDH1A1 918/4885 |
| US-20070060569-A1 | Azacycloalkyl substituted acetic acid derivatives for use as MMP inhibitors | MMP9, MMP1, MMP13 | PGR 1955/4885MEN1 3101/4885ALDH1A1 207/4885 |
| US-20200165209-A1 | METHOD FOR PRODUCING 3-ARYLPROPIONAMIDE COMPOUND AND 3-ARYLPROPIONIC ACID ESTER COMPOUND | AADAC, DDT, NAT1 | PGR 2491/4885MEN1 3973/4885ALDH1A1 116/4885 |
| US-20240092780-A1 | ADDUCTS AND DIMER COMPOUNDS SYNTHESIZED USING GK METHOD | DRD2, HNMT, DRD1 | PGR 4362/4885MEN1 2440/4885ALDH1A1 1683/4885 |
| US-11028056-B2 | Method for producing 3-arylpropionamide compound and 3-arylpropionic acid ester compound | AADAC, DDT, NAT1 | PGR 2491/4885MEN1 3973/4885ALDH1A1 116/4885 |
| US-20070049570-A1 | Quinoline derivatives as phosphodiesterase inhibitors | PDE3B, PDE4B, PDE4A | PGR 3285/4885MEN1 2927/4885ALDH1A1 623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.