SCHEMBL52226

SCHEMBL52226

CCOC(=O)c1ccc2c(=O)c3cc(OC)ccc3sc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.56
RAB9A P51151 6/20 0.56
MAPT P10636 6/20 0.56
ALDH1A1 P00352 6/20 0.56
KDM4E B2RXH2 5/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
HPGD P15428 3/20 0.47
HSD17B2 P37059 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
HCRTR1 O43613 2/20 0.41
STAT1 P42224 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29501110 1.00 NPC1 (0.56) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL31544289 0.90 HCRTR1 (0.50) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL29046292 0.87 MAPT (0.55) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL29590299 0.86 CA12 (0.44) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL50803 0.86 CA12 (0.44) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL2357624 0.85 L3MBTL1 (0.59) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL10989791 0.84 ALDH1A1 (0.54) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL11633998 0.84 ALDH1A1 (0.63) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL10996056 0.83 RAB9A (0.42) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL28412146 0.82 SMN1; SMN2 (0.41) NPC1RAB9AMAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 677 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11382868-B2 Transdermal UV-curable hydrogel resin, hydrogel curing the same and cataplasm containing the same ICURE PHARMACEUTICAL INC. (KR) 2022-07-12 US claimed
CN-107652222-B Oxime ester photoinitiators 巴斯夫欧洲公司 2021-09-10 CN claimed
US-10919909-B2 Photoinitiated reactions LINTFIELD LIMITED (GB) 2021-02-16 US claimed
US-20190211031-A1 PHOTOINITIATED REACTIONS LINTFIELD LIMITED (GB) 2019-07-11 US claimed
US-20190046463-A1 ULTRAVIOLET-HARDENING HYDROGEL RESIN AND HYDROGEL FOR TRANSDERMAL ADMINISTRATION, AND CATAPLASM AGENT CONTAINING SAME ICURE PHARMACEUTICAL INC. (KR) 2019-02-14 US claimed
EP-3415141-A1 ULTRAVIOLET-HARDENING HYDROGEL RESIN AND HYDROGEL FOR TRANSDERMAL ADMINISTRATION, AND CATAPLASM AGENT CONTAINING SAME Icure Pharmaceutical Inc. (KR) 2018-12-19 EP claimed
US-7740482-B2 Stable cationically crosslinkable/polymerizable dental composition with a high filler content BLUESTAR SILICONES FRANCE (FR) 2010-06-22 US claimed
EP-1745083-B1 HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION BLUESTAR SILICONES FRANCE (FR) 2009-12-16 EP claimed
US-20080287562-A1 Stable cationically crosslinkable/polymerizable dental composition with a high filler content RHODIA CHIMIE (FR) 2008-11-20 US claimed
EP-1745083-A1 HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION Rhodia Chimie (FR) 2007-01-24 EP claimed
WO-2005121200-A1 HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION RHODIA CHIMIE (FR) 2005-12-22 WO claimed
US-20050261390-A1 Stable cationically crosslinkable/polymerizable dental composition with a high filler content RHODIA CHIMIE (FR) 2005-11-24 US claimed
US-12637600-B2 Photocurable composition, cured product of same, photofusible resin composition and adhesive set RESONAC CORPORATION (JP) 2026-05-26 US disclosed
US-20260132243-A1 THERMOSETTING COMPOSITION AND CURED PRODUCT THEREOF, PHOTOMELTABLE COMPOSITION, AND STRUCTURAL BODY PRODUCTION METHOD RESONAC CORP (JP) 2026-05-14 US disclosed
EP-4410859-B1 THERMOSETTING COMPOSITION AND CURED PRODUCT THEREOF, PHOTO-MELTABLE COMPOSITION, AND STRUCTURAL BODY PRODUCTION METHOD RESONAC CORP (JP) 2026-04-29 EP disclosed
US-20260051498-A1 Electrode for Lithium Secondary Battery and Method for Manufacturing the Same LG CHEM, LTD. (KR) 2026-02-19 US disclosed
EP-0088050-B1 COLOURED PHOTO-HARDENABLE COMPOSITION CIBA-GEIGY AG (CH) 1986-09-03 EP disclosed
US-4582862-A QUICK-SETTING PRINTING INKS BASED ON ACRYLATED RESINS CIBA-GEIGY CORPORATION (US) 1986-04-15 US disclosed
EP-0138754-A2 Photocurable compositions CIBA-GEIGY AG (CH) 1985-04-24 EP disclosed
EP-0088050-A2 Coloured photo-hardenable composition CIBA-GEIGY AG (CH) 1983-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637600-B2 Photocurable composition, cured product of same, photofusible resin composition and adhesive set ESD, CDH1, ASH2L NPC1 4105/4885RAB9A 4022/4885MAPT 2260/4885
US-20080287562-A1 Stable cationically crosslinkable/polymerizable dental composition with a high filler content RFC1, RFC2, HNRNPC NPC1 3522/4885RAB9A 509/4885MAPT 3057/4885
US-10919909-B2 Photoinitiated reactions KMO, DECR1, PPOX NPC1 2000/4885RAB9A 3269/4885MAPT 1604/4885
US-20190211031-A1 PHOTOINITIATED REACTIONS DOHH, PAH, DBH NPC1 2594/4885RAB9A 4138/4885MAPT 1061/4885
US-20260051498-A1 Electrode for Lithium Secondary Battery and Method for Manufacturing the Same ILK, EPCAM, L1CAM NPC1 3910/4885RAB9A 1131/4885MAPT 1384/4885
US-20260132243-A1 THERMOSETTING COMPOSITION AND CURED PRODUCT THEREOF, PHOTOMELTABLE COMPOSITION, AND STRUCTURAL BODY PRODUCTION METHOD RER1, OXTR, MAP1LC3A NPC1 4792/4885RAB9A 3549/4885MAPT 235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.