SCHEMBL55866

SCHEMBL55866

CCO[Si](CCCCl)(OC)OCC

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11239435 0.95 LMNA (0.34) LMNATSHRTDP1
SCHEMBL4729324 0.93 LMNA (0.37) LMNATSHRTDP1
SCHEMBL11225639 0.90 LMNA (0.33) LMNATSHRTDP1
SCHEMBL17472889 0.90 LMNA (0.35) LMNA
SCHEMBL56580 0.88 TSHR (0.36) TSHRTDP1
Hydrogen Sulfide SCHEMBL28262972 0.86 TSHR (0.35) TSHRTDP1
SCHEMBL21633521 0.86 TSHR (0.35) TSHRTDP1
SCHEMBL28232064 0.86 TSHR (0.35) TSHRTDP1
SCHEMBL56736 0.86
Ammonia Solution, Strong SCHEMBL8577957 0.86 TSHR (0.35) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8138365-B2 Method for producing organosilanes EVONIK DEGUSSA GMBH (DE) 2012-03-20 US claimed
US-20100217026-A1 Method for producing organosilanes EVONIK OPERATIONS GMBH (DE) 2010-08-26 US claimed
US-12600735-B2 Method for producing polysulphane-silanes by means of phase transfer catalysis EVONIK OPERATIONS GMBH (DE) 2026-04-14 US disclosed
US-12540146-B2 Process for the production of sulfur containing silanes by utilization of phase transfer catalysis EVONIK OPERATIONS GMBH (DE) 2026-02-03 US disclosed
EP-3862359-B1 METHOD FOR PRODUCING POLYSULFANE SILANES EVONIK OPERATIONS GMBH (DE) 2024-04-03 EP disclosed
EP-4100414-B1 A PROCESS FOR THE PRODUCTION OF SULFUR CONTAINING SILANES BY UTILIZATION OF PHASE TRANSFER CATALYSIS EVONIK OPERATIONS GMBH (DE) 2023-10-11 EP disclosed
US-20230265113-A1 PROCESS FOR PREPARING POLYSULFANE SILANES BY MEANS OF PHASE TRANSFER CATALYSIS EVONIK OPERATIONS GMBH (DE) 2023-08-24 US disclosed
EP-4208469-A1 PROCESS FOR PREPARING POLYSULFANE SILANES BY MEANS OF PHASE TRANSFER CATALYSIS Evonik Operations GmbH (DE) 2023-07-12 EP disclosed
US-11697659-B2 Process for preparing polysulfane silanes EVONIK OPERATIONS GMBH (DE) 2023-07-11 US disclosed
US-20230037594-A1 A PROCESS FOR THE PRODUCTION OF SULFUR CONTAINING SILANES BY UTILIZATION OF PHASE TRANSFER CATALYSIS EVONIK OPERATIONS GMBH (DE) 2023-02-09 US disclosed
US-20230039979-A1 METHOD FOR PRODUCING POLYSULPHANE-SILANES BY MEANS OF PHASE TRANSFER CATALYSIS EVONIK OPERATIONS GMBH (DE) 2023-02-09 US disclosed
US-20020123640-A1 CONTINUOUS TRANSESTERIFICATION PROCESS FOR ALKOXYORGANOSILICON COMPOUNDS CROMPTON CORPORATION 2002-09-05 US disclosed
US-20010051739-A1 LOW-SULFUR POLYSULFIDE SILANES AND PROCESS FOR PREPARATION MOMENTIVE PERFORMANCE MATERIALS INC. 2001-12-13 US disclosed
WO-2001074825-A1 LOW-SULFUR POLYSULFIDE SILANES AND PROCESS FOR PREPARATION CROMPTON CORPORATION (US) 2001-10-11 WO disclosed
EP-0705838-B1 Process for the preparation of silane polysulfides CROMPTON CORP (US) 2001-05-23 EP disclosed
US-5596116-A Process for the preparation of silane polysulfides OSI SPECIALTIES, INC. (US) 1997-01-21 US disclosed
EP-0705838-A2 Process for the preparation of silane polysulfides OSi SPECIALTIES, INC. (US) 1996-04-10 EP disclosed
US-5489701-A REACTING SULFUR AND A HALOHYDROCARBYLALKOXYSILANE WITH THE REACTION PRODUCT OF HYDROGEN SULFIDE GAS AND A METAL ALKOXIDE SOLUTION OSI SPECIALTIES, INC. (US) 1996-02-06 US disclosed
US-5466848-A Sulfiding sodium ethoxide with hydrogen sulfide to make sodium sulfide; reacting with sulfur to tetrasulfide; reacting with halohydrocarbylalkoxysilane OSI SPECIALTIES, INC. (US) 1995-11-14 US disclosed
US-4318819-A Chiral supports for resolution of racemates UOP INC. (US) 1982-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265113-A1 PROCESS FOR PREPARING POLYSULFANE SILANES BY MEANS OF PHASE TRANSFER CATALYSIS MRPS22, MRPS23, SRM LMNA 3783/4885TSHR 1690/4885TDP1 3958/4885
US-20020123640-A1 CONTINUOUS TRANSESTERIFICATION PROCESS FOR ALKOXYORGANOSILICON COMPOUNDS ADH1A, ADH5, ADH1C LMNA 1566/4885TSHR 2076/4885TDP1 2623/4885
US-20100217026-A1 Method for producing organosilanes TST, STS, HAO2 LMNA 4751/4885TSHR 881/4885TDP1 4435/4885
US-12600735-B2 Method for producing polysulphane-silanes by means of phase transfer catalysis MSR1, AS3MT, RRM1 LMNA 1808/4885TSHR 892/4885TDP1 4247/4885
US-11697659-B2 Process for preparing polysulfane silanes MSR1, SFXN1, SFXN3 LMNA 3922/4885TSHR 1665/4885TDP1 4749/4885
US-20230039979-A1 METHOD FOR PRODUCING POLYSULPHANE-SILANES BY MEANS OF PHASE TRANSFER CATALYSIS SMOX, TST, MRPS22 LMNA 3776/4885TSHR 2057/4885TDP1 3658/4885
US-20230037594-A1 A PROCESS FOR THE PRODUCTION OF SULFUR CONTAINING SILANES BY UTILIZATION OF PHASE TRANSFER CATALYSIS TST, CTH, SF3A1 LMNA 3532/4885TSHR 3227/4885TDP1 2581/4885
US-12540146-B2 Process for the production of sulfur containing silanes by utilization of phase transfer catalysis TST, SFN, SAMM50 LMNA 3503/4885TSHR 2537/4885TDP1 3657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.