Hydroquinone

Hydroquinone

SCHEMBL7209920

O=S(=O)(O)O.Oc1ccc(O)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Hydroquinone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.67
ALOX15 P16050 4/20 0.62
HPGD P15428 3/20 0.62
ALDH1A1 P00352 3/20 0.62
CYP3A4 P08684 3/20 0.62
HIF1A Q16665 3/20 0.62
HSD17B10 Q99714 3/20 0.62
RECQL P46063 2/20 0.62
THRB P10828 2/20 0.62
CASP1 P29466 2/20 0.62
TP53 P04637 1/20 0.62
CA2 P00918 5/20 0.61
CA1 P00915 4/20 0.61
CA12 O43570 3/20 0.61
CA9 Q16790 3/20 0.61
CA5A P35218 3/20 0.61
CA5B Q9Y2D0 3/20 0.61
CA3 P07451 3/20 0.61
CA14 Q9ULX7 3/20 0.61
MAPT P10636 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL22190068 0.96 LMNA (0.63) LMNAALOX15HPGDALDH1A1CYP3A4
Hydroquinone SCHEMBL28381927 0.96 LMNA (0.63) LMNAALOX15HPGDALDH1A1CYP3A4
Hydroquinone SCHEMBL27973638 0.87 LMNA (0.55) LMNAALOX15HPGDALDH1A1CYP3A4
Hydroquinone SCHEMBL28903112 0.86 ENPP2 (0.65) LMNAALOX15HPGDALDH1A1CYP3A4
Hydroquinone SCHEMBL575590 0.86 ENPP2 (0.65) LMNAALOX15HPGDALDH1A1CYP3A4
4-Aminophenol SCHEMBL17436623 0.85 ALDH1A1 (0.72) LMNAALOX15HPGDALDH1A1CYP3A4
P-Cresol SCHEMBL195722 0.85 ACHE (0.72) LMNAALOX15HPGDALDH1A1CYP3A4
Phenolsulfonic Acid SCHEMBL9682015 0.85 LMNA (0.94) LMNAALOX15HPGDALDH1A1CYP3A4
Parachlorophenol SCHEMBL29039840 0.85 MAPK1 (0.58) LMNAALOX15HPGDALDH1A1CYP3A4
Sulfuric Acid SCHEMBL8007761 0.85 LMNA (0.67) LMNAALOX15HPGDALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117822072-A Tin-silver-copper alloy electroplating solution and electroplating method for wafer-level bump interconnection 大连理工大学 2024-04-05 CN claimed
CN-116396449-A Method for synthesizing polycarboxylate superplasticizer 贵州凯襄新材料有限公司 2023-07-07 CN claimed
CN-116199839-A Sulfonated polyether-ether-ketone polymer and preparation method thereof 常州大学 2023-06-02 CN claimed
CN-112444581-B High-safety hydroquinone composition purification method 广东人人康药业有限公司 2023-03-17 CN claimed
CN-112022806-B Water-in-oil hydroquinone emulsion and preparation method and application thereof 广东人人康药业有限公司 2022-04-15 CN claimed
CN-111995500-B Preparation method and application of high-safety hydroquinone composition 广东人人康药业有限公司 2022-04-15 CN claimed
CN-112125785-B High-safety hydroquinone composition purification method and application thereof 广东人人康药业有限公司 2022-02-18 CN claimed
CN-112076096-B Hydroquinone three-phase emulsion and preparation method and application thereof 广东人人康药业有限公司 2021-12-28 CN claimed
US-20210353611-A1 METHODS OF TREATING AMYOTROPHIC LATERAL SCLEROSIS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-11-18 US claimed
EP-3852759-A2 METHODS OF TREATING AMYOTROPHIC LATERAL SCLEROSIS Yeda Research and Development Co. Ltd (IL) 2021-07-28 EP claimed
CN-113038951-A Method of treating amyotrophic lateral sclerosis 耶达研究及发展有限公司 2021-06-25 CN claimed
CN-108251063-B High-performance composite phase-change material and preparation method thereof 有研工程技术研究院有限公司 2021-05-11 CN claimed
CN-112334165-A Stabilized hyaluronic acid 克罗马药品有限责任公司 2021-02-05 CN claimed
WO-2020058979-A2 METHODS OF TREATING AMYOTROPHIC LATERAL SCLEROSIS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2020-03-26 WO claimed
CN-101039683-A Compositions and methods using hyaluronic acid and hyaluronidase inhibitors ANGIOTECH INT AG (CH) 2007-09-19 CN claimed
US-20260034086-A1 Pet Food Compositions Comprising Caprylic Acid And Docosahexaenoic Acid And/Or Eicosapetaenoic Acid For Use In Treating Struvite Urolithiasis HILL'S PET NUTRITION, INC. (US) 2026-02-05 US disclosed
US-20250375505-A1 COMPOSITIONS AND METHODS FOR MODIFYING BILE ACIDS TO REGULATE LIPID AND STEROID METABOLISM UNIV CALIFORNIA (US) 2025-12-11 US disclosed
US-4434226-A CONCURRENT ADDITION OF SILVER, BROMIDE, IODIDE SALTS EASTMAN KODAK COMPANY (US) 1984-02-28 US disclosed
US-4433048-A TABULAR GRAINS EASTMAN KODAK COMPANY (US) 1984-02-21 US disclosed
US-4414306-A TABULAR GRAINS EASTMAN KODAK COMPANY (US) 1983-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250375505-A1 COMPOSITIONS AND METHODS FOR MODIFYING BILE ACIDS TO REGULATE LIPID AND STEROID METABOLISM CYP27A1, LIPC, CYP46A1 LMNA 2028/4885ALOX15 632/4885HPGD 1089/4885
US-20260034086-A1 Pet Food Compositions Comprising Caprylic Acid And Docosahexaenoic Acid And/Or Eicosapetaenoic Acid For Use In Treating Struvite Urolithiasis FPR2, FPR1, FPR3 LMNA 1957/4885ALOX15 184/4885HPGD 427/4885
US-20210353611-A1 METHODS OF TREATING AMYOTROPHIC LATERAL SCLEROSIS SMN1; SMN2, SOD1, OAT LMNA 810/4885ALOX15 383/4885HPGD 754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.