Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 known ✓ | P30556 | 1/20 | 0.56 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.59 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.59 |
| ▸ | AKT1 | P31749 | 2/20 | 0.56 |
| ▸ | CDC25A | P30304 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL3392001 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| Potassium Ion SCHEMBL3411903 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| Potassium Ion SCHEMBL122618 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| Hexadecyl Dihydrogen Phosphate SCHEMBL61626 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| Potassium Ion SCHEMBL27822 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| Potassium Ion SCHEMBL3851846 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| Potassium Ion SCHEMBL11137453 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| Potassium Ion SCHEMBL3409563 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| Phosphoric Acid Monotetradecyl Ester SCHEMBL3094298 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| Potassium Ion SCHEMBL29433163 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5954844-A | BACKING SUPPORTING SURFACE-BOUND ABRASIVE PARTICLES AND ANTILOADING COMPOUND COMPRISING AN ALKYLATED OR FLUOROALKYLATED ORGANOBORON, ORGANONITROGEN, ORGANOPHOSPHORUS, ORGANOSULFUR, OR HYDROXYCARBOXYLIC ACID DERIVATIVE | MINNESOTA MINING & MANUFACTURING COMPANY (US) | 1999-09-21 | — | — | US | claimed |
| EP-0912295-A1 | ABRASIVE ARTICLE COMPRISING AN ANTILOADING COMPONENT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-05-06 | — | — | EP | claimed |
| US-5704952-A | COATINGS, BONDING, NONWOVEN ABRASIVES AND BINDERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-01-06 | — | — | US | claimed |
| WO-1997042007-A1 | ABRASIVE ARTICLE COMPRISING AN ANTILOADING COMPONENT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-11-13 | — | — | WO | claimed |
| US-20260145300-A1 | ABRASIVE ARTICLES AND METHODS OF MAKING AND USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2026-05-28 | — | — | US | disclosed |
| US-12629798-B2 | Abrasive articles and method of making the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2026-05-19 | — | — | US | disclosed |
| US-12576482-B2 | Porous coated abrasive article and method of making the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2026-03-17 | — | — | US | disclosed |
| US-20260027675-A1 | CURABLE COMPOSITION, TREATED BACKING, COATED ABRASIVE ARTICLES INCLUDING THE SAME, AND METHODS OF MAKING AND USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2026-01-29 | — | — | US | disclosed |
| US-12528158-B2 | Abrasive article and method of making the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2026-01-20 | — | — | US | disclosed |
| EP-4633864-A1 | ABRASIVE ARTICLES AND METHODS OF MANUFACTURE THEREOF | 3M Innovative Properties Company (US) | 2025-10-22 | — | — | EP | disclosed |
| US-20250276424-A1 | ABRASIVE ARTICLES, METHODS OF MANUFACTURE AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY | 2025-09-04 | — | — | US | disclosed |
| EP-4397667-B1 | IMPROVED SUSTAINABLE PROCESS FOR PREPARATION OF PHOSPHORIC MONOESTERS AND SALTS THEREOF | GALAXY SURFACTANTS LTD (IN) | 2025-07-23 | — | — | EP | disclosed |
| WO-2022023845-A1 | ABRASIVE ARTICLE AND METHOD OF MAKING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2022-02-03 | — | — | WO | disclosed |
| US-20210408545-A1 | BINDER COMPOSITION FOR ALL-SOLID-STATE SECONDARY BATTERY, SLURRY COMPOSITION FOR ALL-SOLID-STATE SECONDARY BATTERY, SOLID ELECTROLYTE-CONTAINING LAYER, AND ALL-SOLID-STATE SECONDARY BATTERY | ZEON CORPORATION (JP) | 2021-12-30 | — | — | US | disclosed |
| EP-3859857-A1 | ALL-SOLID SECONDARY BATTERY BINDER COMPOSITION, ALL-SOLID SECONDARY BATTERY SLURRY COMPOSITION, SOLID-ELECTROLYTE-CONTAINING LAYER, AND ALL-SOLID SECONDARY BATTERY | Zeon Corporation (JP) | 2021-08-04 | — | — | EP | disclosed |
| WO-2020066952-A1 | ALL-SOLID SECONDARY BATTERY BINDER COMPOSITION, ALL-SOLID SECONDARY BATTERY SLURRY COMPOSITION, SOLID-ELECTROLYTE-CONTAINING LAYER, AND ALL-SOLID SECONDARY BATTERY | 日本ゼオン株式会社 | 2020-04-02 | — | — | WO | disclosed |
| US-5954844-A | BACKING SUPPORTING SURFACE-BOUND ABRASIVE PARTICLES AND ANTILOADING COMPOUND COMPRISING AN ALKYLATED OR FLUOROALKYLATED ORGANOBORON, ORGANONITROGEN, ORGANOPHOSPHORUS, ORGANOSULFUR, OR HYDROXYCARBOXYLIC ACID DERIVATIVE | MINNESOTA MINING & MANUFACTURING COMPANY (US) | 1999-09-21 | — | — | US | disclosed |
| EP-0912295-A1 | ABRASIVE ARTICLE COMPRISING AN ANTILOADING COMPONENT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-05-06 | — | — | EP | disclosed |
| US-5704952-A | COATINGS, BONDING, NONWOVEN ABRASIVES AND BINDERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-01-06 | — | — | US | disclosed |
| WO-1997042007-A1 | ABRASIVE ARTICLE COMPRISING AN ANTILOADING COMPONENT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12528158-B2 | Abrasive article and method of making the same | ITGAV, ILK, ITGA2 | AGTR1 3368/4885LPAR3 4749/4885LPAR2 4189/4885 |
| US-20260027675-A1 | CURABLE COMPOSITION, TREATED BACKING, COATED ABRASIVE ARTICLES INCLUDING THE SAME, AND METHODS OF MAKING AND USING THE SAME | ELL, FHIT, ALKBH2 | AGTR1 1748/4885LPAR3 4695/4885LPAR2 4421/4885 |
| US-20260145300-A1 | ABRASIVE ARTICLES AND METHODS OF MAKING AND USING THE SAME | PRPF40A, PUF60, GIGYF2 | AGTR1 1508/4885LPAR3 4366/4885LPAR2 4151/4885 |
| US-12629798-B2 | Abrasive articles and method of making the same | DCX, ITGA1, FN1 | AGTR1 3014/4885LPAR3 2990/4885LPAR2 2322/4885 |
| US-12576482-B2 | Porous coated abrasive article and method of making the same | FLNB, MFAP1, FLNA | AGTR1 2917/4885LPAR3 2503/4885LPAR2 1612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.