Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28986126 | 0.79 | MTOR (0.62) | MTORALOX5GAALIMK2TRPM8 | |
| SCHEMBL1520362 | 0.79 | MTOR (0.62) | MTORALOX5GAALIMK2TRPM8 | |
| SCHEMBL22956851 | 0.78 | AOC3 (0.53) | GAALMNAKDM4EALDH1A1MEN1 | |
| SCHEMBL12830195 | 0.77 | MTOR (0.61) | MTORALOX5GAALIMK2TRPM8 | |
| SCHEMBL12269652 | 0.77 | MTOR (0.61) | MTORALOX5GAALIMK2TRPM8 | |
| SCHEMBL6512237 | 0.77 | MTOR (0.61) | MTORALOX5GAALIMK2TRPM8 | |
| SCHEMBL26638352 | 0.77 | MTOR (0.61) | MTORALOX5GAALIMK2TRPM8 | |
| SCHEMBL8383968 | 0.76 | ALOX5 (0.41) | MTORALOX5LMNATRPM8CYP2C19 | |
| SCHEMBL12783364 | 0.76 | MTOR (0.59) | MTORALOX5GAALIMK2TRPM8 | |
| SCHEMBL20901376 | 0.76 | MTOR (0.59) | MTORALOX5GAALIMK2TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DENTSPLY SIRONA INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-20220202658-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2022-06-30 | — | — | US | disclosed |
| US-20220031576-A1 | ADDITIVE MANUFACTURING PROCESS | DENTSPLY SIRONA INC. (US) | 2022-02-03 | — | — | US | disclosed |
| US-11224557-B2 | Dental composition | DENTSPLY SIRONA INC (US) | 2022-01-18 | — | — | US | disclosed |
| US-20220000721-A1 | BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS | DENTSPLY SIRONA INC. (US) | 2022-01-06 | — | — | US | disclosed |
| EP-3359119-B1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2021-12-29 | — | — | EP | disclosed |
| US-11166883-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2021-11-09 | — | — | US | disclosed |
| US-11141357-B2 | Dental adhesive | DENTSPLY SIRONA INC. (US) | 2021-10-12 | — | — | US | disclosed |
| US-11116702-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2021-09-14 | — | — | US | disclosed |
| US-11110039-B2 | Macromonomer based light-curable dental impression material | DENTSPLY SIRONA INC. (US) | 2021-09-07 | — | — | US | disclosed |
| EP-3231412-A2 | AQUEOUS DENTAL GLASS IONOMER COMPOSITION | DENTSPLY DETREY GmbH (DE) | 2017-10-18 | — | — | EP | disclosed |
| EP-0910351-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0907666-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997049736-A2 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| WO-1997049387-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| US-5281750-A | Deracemization and optical inversion using polymer supports | RHONE-POULENC CHIMIE (FR) | 1994-01-25 | — | — | US | disclosed |
| US-4681919-A | Polymerizable, optically active polymer and process for preparing polymerizable polymer | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1987-07-21 | — | — | US | disclosed |
| EP-0095086-B1 | POLYMERIZABLE, OPTICALLY ACTIVE POLYMER AND PROCESS FOR PREPARING POLYMERIZABLE POLYMER | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1986-04-09 | — | — | EP | disclosed |
| US-4554323-A | Polymerizable, optically active polymer and process for preparing polymerizable polymer | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1985-11-19 | — | — | US | disclosed |
| EP-0095086-A1 | Polymerizable, optically active polymer and process for preparing polymerizable polymer | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1983-11-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11224557-B2 | Dental composition | GPX4, GPX1, NOXO1 | MTOR 3470/4885ALOX5 541/4885GAA 3279/4885 |
| US-11141357-B2 | Dental adhesive | CDH1, ITGA5, ICAM1 | MTOR 4885/4885ALOX5 224/4885GAA 2779/4885 |
| US-20220202658-A1 | DENTAL COMPOSITION | CAD, PHOSPHO1, PLA2G2C | MTOR 3106/4885ALOX5 524/4885GAA 363/4885 |
| US-20220000721-A1 | BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS | DUOX2, DUOX1, QSOX1 | MTOR 4716/4885ALOX5 2184/4885GAA 2841/4885 |
| US-11110039-B2 | Macromonomer based light-curable dental impression material | EPM2A, LMNB1, LMNB2 | MTOR 3585/4885ALOX5 2127/4885GAA 1726/4885 |
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DHX35, DHX30, FLNA | MTOR 4786/4885ALOX5 998/4885GAA 855/4885 |
| US-11116702-B2 | Dental composition | MTR, CAD, PAM | MTOR 2181/4885ALOX5 404/4885GAA 4524/4885 |
| US-11166883-B2 | Dental composition | MSR1, TAS2R3, TAS2R39 | MTOR 1856/4885ALOX5 4069/4885GAA 3902/4885 |
| US-20220031576-A1 | ADDITIVE MANUFACTURING PROCESS | FLNA, FLNB, SAMM50 | MTOR 3891/4885ALOX5 2062/4885GAA 1183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.