Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CTH | P32929 | 1/20 | 0.38 |
| ▸ | CBS | P35520 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11798630 | 0.97 | ALDH1A1 (0.36) | TSHRALDH1A1CTHCBSTHPO | |
| Lithium Ion SCHEMBL28864518 | 0.95 | TSHR (0.38) | TSHRALDH1A1CTHCBSTHPO | |
| Sulfurous Acid SCHEMBL28007837 | 0.89 | ALDH1A1 (0.32) | TSHRALDH1A1CTHCBSTHPO | |
| SCHEMBL10823123 | 0.77 | RECQL (0.35) | TSHRALDH1A1RECQLGLAHPGD | |
| SCHEMBL693135 | 0.75 | TSHR (0.43) | TSHRALDH1A1CTHCBSTHPO | |
| SCHEMBL1902608 | 0.74 | RECQL (0.32) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL524292 | 0.74 | RECQL (0.32) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL5571006 | 0.74 | RECQL (0.32) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL168709 | 0.72 | — | — | |
| SCHEMBL7605884 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112631072-A | Sulfonium salt photo-acid generator synthesized from 10-hydroxy climbing mountain orange alkali and preparation method thereof | 上海博栋化学科技有限公司 | 2021-04-09 | — | — | CN | claimed |
| CN-112552298-A | Sulfonium salt photo-acid generator synthesized from 16-epi-NB-methyl Voacarpine base and preparation method thereof | 上海博栋化学科技有限公司 | 2021-03-26 | — | — | CN | claimed |
| CN-104057564-B | Based on the micropin manufacture method tilting mold | 游学秋 | 2016-08-03 | — | — | CN | claimed |
| EP-4314218-B1 | FABRIC CONDITIONER COMPOSITION | UNILEVER IP HOLDINGS B V (NL) | 2026-02-04 | — | — | EP | disclosed |
| US-12534688-B2 | Fabric softener composition comprising a betaine ester and a fatty co-softener | CONOPCO, INC. (US) | 2026-01-27 | — | — | US | disclosed |
| US-12522560-B2 | Quaternary ammonium compounds | SPECIALTY OPERATIONS FRANCE (FR) | 2026-01-13 | — | — | US | disclosed |
| US-12503671-B2 | Fabric conditioner composition | CONOPCO, INC. (US) | 2025-12-23 | — | — | US | disclosed |
| EP-4041855-B1 | FABRIC SOFTENER | UNILEVER IP HOLDINGS B V (NL) | 2025-08-06 | — | — | EP | disclosed |
| EP-4041854-B1 | FABRIC SOFTENER | UNILEVER IP HOLDINGS B V (NL) | 2025-07-30 | — | — | EP | disclosed |
| US-20250092313-A1 | MIXTURES OF CLEAVABLE QUATERNARY AMMONIUM COMPOUNDS USEFUL AS SURFACTANTS | SPECIALTY OPERATIONS FRANCE (FR) | 2025-03-20 | — | — | US | disclosed |
| CN-114616374-B | Fabric softener | 联合利华知识产权控股有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-114502706-A | Fabric softener | 联合利华知识产权控股有限公司 | 2022-05-13 | — | — | CN | disclosed |
| EP-3986857-A1 | NEW QUATERNARY AMMONIUM COMPOUNDS | RHODIA OPERATIONS (FR) | 2022-04-27 | — | — | EP | disclosed |
| CN-114096513-A | Novel quaternary ammonium compounds | 罗地亚经营管理公司 | 2022-02-25 | — | — | CN | disclosed |
| WO-2021132022-A1 | MICRONEEDLE ARRAY PRODUCTION METHOD | 富士フイルム株式会社 | 2021-07-01 | — | — | WO | disclosed |
| CN-112679514-A | Sulfonium salt photo-acid generator synthesized from papaya alkali and preparation method thereof | 上海博栋化学科技有限公司 | 2021-04-20 | — | — | CN | disclosed |
| CN-105236809-A | Cement grinding aid | CHONGQING NANCHUAN DISTR HAIFENG CEMENT CO LTD | 2016-01-13 | — | — | CN | disclosed |
| US-5816938-A | INCREASE FLYING DISTANCE | BRIDGESTONE SPORTS CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-4294711-A | STILBENE OPTICAL BRIGHTENERS AND SURFACTANTS | THE PROCTER & GAMBLE COMPANY (US) | 1981-10-13 | — | — | US | disclosed |
| US-4291071-A | POLYPHOSPHONATES, BUILDERS, SOFTENERS, DETERGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1981-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12534688-B2 | Fabric softener composition comprising a betaine ester and a fatty co-softener | COL2A1, LBR, YWHAZ | THRB 1441/4885TSHR 3891/4885ALDH1A1 2059/4885 |
| US-20250092313-A1 | MIXTURES OF CLEAVABLE QUATERNARY AMMONIUM COMPOUNDS USEFUL AS SURFACTANTS | NSF, ACMSD, SENP7 | THRB 4730/4885TSHR 4224/4885ALDH1A1 4649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.