SCHEMBL10016618

SCHEMBL10016618

CN(C1CCCCC1)C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 7/20 0.42
ADH1C P00326 4/20 0.42
PHGDH O43175 2/20 0.38
FAAH O00519 1/20 0.38
MGLL Q99685 1/20 0.38
ADH1B P00325 1/20 0.33
HRH4 Q9H3N8 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
RAB9A P51151 1/20 0.33
KDM4E B2RXH2 2/20 0.32
SIGMAR1 Q99720 1/20 0.32
ALDH1A1 P00352 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31618698 1.00 ADH1A (0.42) ADH1AADH1CPHGDHFAAHMGLL
SCHEMBL12227420 0.97 ADH1A (0.39) ADH1AADH1CPHGDHFAAHMGLL
SCHEMBL10453704 0.94 ADH1C (0.35) ADH1AADH1CPHGDHFAAHMGLL
SCHEMBL4569251 0.85
SCHEMBL19143717 0.79 PHGDH (0.40) ADH1AADH1CPHGDHFAAHMGLL
SCHEMBL19333233 0.79 ADH1A (0.39) ADH1AADH1CPHGDHFAAHMGLL
SCHEMBL12543353 0.79 ADH1A (0.39) ADH1AADH1CPHGDHFAAHMGLL
SCHEMBL12543486 0.76 ADH1A (0.36) ADH1AADH1CPHGDHFAAHMGLL
SCHEMBL19733305 0.76
SCHEMBL18433477 0.75 ADH1A (0.39) ADH1AADH1CPHGDHFAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136646-A Method for synthesizing benzyl alkyl ketone compound by visible light catalysis 中国科学院化学研究所 2025-06-13 CN claimed
CN-120136646-A Method for synthesizing benzyl alkyl ketone compound by visible light catalysis 中国科学院化学研究所 2025-06-13 CN disclosed
US-20240238265-A1 ADAMANTANE AMIDES AND THIOAMIDES FOR THE TREATMENT OF EBOLAVIRUS INFECTION ARISAN THERAPEUTICS INC. (US) 2024-07-18 US disclosed
US-11858940-B2 Selective modulators of mutant LRRK2 proteolysis and associated methods of use ARVINAS OPERATIONS, INC. (US) 2024-01-02 US disclosed
US-20230286997-A1 Compounds for the Treatment of Cancer and Inflammatory Disease SHY Therapeutics LLC 2023-09-14 US disclosed
US-20230286997-A1 Compounds for the Treatment of Cancer and Inflammatory Disease SHY Therapeutics LLC 2023-09-14 US disclosed
US-20230256098-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2023-08-17 US disclosed
US-20230256098-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2023-08-17 US disclosed
US-11679158-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2023-06-20 US disclosed
US-11679158-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2023-06-20 US disclosed
US-20100048594-A1 USE OF CYTOHESIN INHIBITORS FOR CHEMICALLY INDUCING LONGEVITY RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITAT (DE) 2010-02-25 US disclosed
US-20100022533-A1 COMPOSITIONS AND METHODS FOR INDUCING CELL DEDIFFERENTIATION THE SCRIPPS RESEARCH INSTITUTE (US) 2010-01-28 US disclosed
US-20090253682-A1 HETEROCYCLIC DERIVATIVES FOR MODULATION OF CALCIUM CHANNELS VERTEX PHARMACEUTICALS INCORPORATED 2009-10-08 US disclosed
US-7592177-B2 2-(4-morpholinoanilino)-6-cyclohexylamino-purine; contacting a lineage committed cell (myoblast) with cell dedifferentiates into a multipotent stem cell; for repair of damaged tissues; cardiovascular, neurodegenerative disease and aging; small molecules THE SCRIPPS RESEARCH INSTITUTE (US) 2009-09-22 US disclosed
US-7569604-B2 Heterocyclic derivatives for modulation of calcium channels VERTEX PHARMACEUTICALS INCORPORATED (US) 2009-08-04 US disclosed
US-20090105286-A1 Low-molecular inhibitors of cytohesin-family guanine nucleotide exchange factors RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITAT (DE) 2009-04-23 US disclosed
US-7326703-B2 (1,10B-Dihydro-2-(aminocarbonyl-phenyl)-5H-pyrazolo[1,5-c][1,3]benzoxazin-5-yl)phenyl methanone derivatives as HIV viral replication inhibitors TIBOTEC PHARMACEUTICALS LTD (IL) 2008-02-05 US disclosed
US-20070254884-A1 Compositions and Methods for Inducing Cell Dedifferentiation THE SCRIPPS RESEARCH INSTITUTE 2007-11-01 US disclosed
US-20070248624-A1 (1,10B-Dihydro-2-(Aminocarbonyl-Phenyl)-5h-Pyrazolo[1,5-C][1,3]Benzoxazin-5-Yl)Phenyl Methanone Derivatives as Hiv Viral Replication Inhibitors JANSSEN SCIENCES IRELAND UC (IE) 2007-10-25 US disclosed
CN-1541995-A Novel method for synthesizing gamma-amino acid 中国科学院成都有机化学研究所 2004-11-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090253682-A1 HETEROCYCLIC DERIVATIVES FOR MODULATION OF CALCIUM CHANNELS CACNA1D, ORAI1, CACNA1C ADH1A 4689/4885ADH1C 4478/4885PHGDH 2418/4885
US-20070254884-A1 Compositions and Methods for Inducing Cell Dedifferentiation PAX3, PAX2, ALPG ADH1A 3157/4885ADH1C 2726/4885PHGDH 1168/4885
US-20100048594-A1 USE OF CYTOHESIN INHIBITORS FOR CHEMICALLY INDUCING LONGEVITY IGFBP1, IGFBP2, IGFBP5 ADH1A 2351/4885ADH1C 1974/4885PHGDH 1135/4885
US-20230286997-A1 Compounds for the Treatment of Cancer and Inflammatory Disease MAPK6, MAP3K6, MAPK4 ADH1A 3789/4885ADH1C 3793/4885PHGDH 578/4885
US-20240238265-A1 ADAMANTANE AMIDES AND THIOAMIDES FOR THE TREATMENT OF EBOLAVIRUS INFECTION IFNAR1, NR4A3, NR0B2 ADH1A 1966/4885ADH1C 3139/4885PHGDH 4327/4885
US-20090105286-A1 Low-molecular inhibitors of cytohesin-family guanine nucleotide exchange factors CYTH2, CYTH3, ENTPD5 ADH1A 4736/4885ADH1C 4782/4885PHGDH 2443/4885
US-11679158-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP ADH1A 2987/4885ADH1C 3071/4885PHGDH 1884/4885
US-20230256098-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP ADH1A 2987/4885ADH1C 3071/4885PHGDH 1884/4885
US-20070248624-A1 (1,10B-Dihydro-2-(Aminocarbonyl-Phenyl)-5h-Pyrazolo[1,5-C][1,3]Benzoxazin-5-Yl)Phenyl Methanone Derivatives as Hiv Viral Replication Inhibitors POLRMT, MAVS, DHX15 ADH1A 919/4885ADH1C 401/4885PHGDH 1479/4885
US-20100022533-A1 COMPOSITIONS AND METHODS FOR INDUCING CELL DEDIFFERENTIATION ALPG, PAX3, RARG ADH1A 1807/4885ADH1C 1574/4885PHGDH 605/4885
US-11858940-B2 Selective modulators of mutant LRRK2 proteolysis and associated methods of use LRRK2, ADRM1, CRBN ADH1A 4617/4885ADH1C 4526/4885PHGDH 3329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.