SCHEMBL1004731

SCHEMBL1004731

C=CCO[PH](=O)OP(=O)(O)O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LPAR2 Q9HBW0 1/20 0.33
LPAR3 Q9UBY5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30384 0.77
SCHEMBL10534019 0.76
SCHEMBL28931612 0.74
Ammonia Solution, Strong SCHEMBL29217970 0.74
SCHEMBL3391417 0.73
SCHEMBL1512980 0.71 FDPS (0.41)
SCHEMBL14764569 0.71 LPAR2 (0.37) LPAR2LPAR3
SCHEMBL27779834 0.70
Cyclohexane SCHEMBL9114841 0.70 MAPT (0.31)
Benzene SCHEMBL1538489 0.70 CYP3A4 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322878-A1 COMPOUNDS FOR INDUCING TISSUE FORMATION AND USES THEREOF HISTIDE AG (CH) 2023-10-12 US disclosed
US-11578110-B2 Compounds for inducing tissue formation and uses thereof HISTIDE AG (CH) 2023-02-14 US disclosed
US-20220267394-A1 COMPOUNDS FOR INDUCING TISSUE FORMATION AND USES THEREOF HISTIDE AG (CH) 2022-08-25 US disclosed
US-20190225651-A1 COMPOUNDS FOR INDUCING TISSUE FORMATION AND USES THEREOF HISTIDE AG (CH) 2019-07-25 US disclosed
US-10201487-B2 Hair cosmetic composition which comprises a plant lecithin BASF SE (DE) 2019-02-12 US disclosed
US-20190016770-A1 COMPOUNDS FOR INDUCING TISSUE FORMATION AND USES THEREOF HISTIDE AG (CH) 2019-01-17 US disclosed
US-20180305408-A1 COMPOUNDS FOR INDUCING TISSUE FORMATION AND USES THEREOF HISTIDE AG (CH) 2018-10-25 US disclosed
US-20180208635-A1 COMPOUNDS FOR INDUCING TISSUE FORMATION AND USES THEREOF HISTIDE AG (CH) 2018-07-26 US disclosed
EP-3341390-A2 COMPOUNDS FOR INDUCING TISSUE FORMATION AND USES THEREOF Histide AG (CH) 2018-07-04 EP disclosed
EP-3341397-A2 COMPOUNDS FOR INDUCING TISSUE FORMATION AND USES THEREOF Histide AG (CH) 2018-07-04 EP disclosed
US-20130123108-A1 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER BASF SE (DE) 2013-05-16 US disclosed
US-20110217255-A1 BLOCK COPOLYMERS AND THEIR USE BASF SE (DE) 2011-09-08 US disclosed
US-20110150796-A1 PRECIPITATION POLYMERIZATION IN THE PRESENCE OF GLYCERIN MONOSTEARATE BASF SE (DE) 2011-06-23 US disclosed
US-20110015280-A1 AMPHOLYTIC COPOLYMER, PRODUCTION THEREOF, AND USE OF THE SAME BASF AKTIENGESELLSCHAFT (DE) 2011-01-20 US disclosed
US-7727445-B2 Method for manufacturing optical film KONICA MINOLTA OPTO, INC. (JP) 2010-06-01 US disclosed
US-20100048655-A1 Comb Polymers and Use Thereof for the Production of Active or Effective Ingredient Formulations BASF SE (DE) 2010-02-25 US disclosed
US-20090230576-A1 Method for Manufacturing Optical Film KONICA MINOLTA OPTO, INC. (JP) 2009-09-17 US disclosed
US-20090041813-A1 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER BASF AKTIENGESELLSCHAFT (DE) 2009-02-12 US disclosed
US-20080227871-A1 Ampholytic Copolymer, Production Thereof, and Use of the Same BASF AKTIENGESELLSCHAFT (DE) 2008-09-18 US disclosed
US-20080187669-A1 Method For Waterproofing Lignocellulosic Materials BASF AKTIENGESELLSCHAFT (DE) 2008-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048655-A1 Comb Polymers and Use Thereof for the Production of Active or Effective Ingredient Formulations MCCC2, C9, C1S LPAR2 2201/4885LPAR3 1710/4885
US-20110217255-A1 BLOCK COPOLYMERS AND THEIR USE FGB, CYBA, PPIB LPAR2 3064/4885LPAR3 2857/4885
US-20110150796-A1 PRECIPITATION POLYMERIZATION IN THE PRESENCE OF GLYCERIN MONOSTEARATE HACL2, DAGLB, HAO2 LPAR2 332/4885LPAR3 923/4885
US-20080227871-A1 Ampholytic Copolymer, Production Thereof, and Use of the Same IDUA, ABHD16A, IDE LPAR2 1392/4885LPAR3 771/4885
US-11578110-B2 Compounds for inducing tissue formation and uses thereof HDGF, HGF, BMP4 LPAR2 357/4885LPAR3 367/4885
US-20190225651-A1 COMPOUNDS FOR INDUCING TISSUE FORMATION AND USES THEREOF SPG11, PTGIS, VIPR1 LPAR2 597/4885LPAR3 643/4885
US-10201487-B2 Hair cosmetic composition which comprises a plant lecithin LRAT, PHOSPHO1, LPCAT1 LPAR2 106/4885LPAR3 58/4885
US-20230322878-A1 COMPOUNDS FOR INDUCING TISSUE FORMATION AND USES THEREOF HDGF, HGF, BMP4 LPAR2 357/4885LPAR3 367/4885
US-20130123108-A1 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER NOS1, NOS3, NPSR1 LPAR2 3381/4885LPAR3 1973/4885
US-20180305408-A1 COMPOUNDS FOR INDUCING TISSUE FORMATION AND USES THEREOF SPHK1, CMKLR1, SPHK2 LPAR2 133/4885LPAR3 286/4885
US-20220267394-A1 COMPOUNDS FOR INDUCING TISSUE FORMATION AND USES THEREOF HDGF, HGF, FGF2 LPAR2 234/4885LPAR3 236/4885
US-20190016770-A1 COMPOUNDS FOR INDUCING TISSUE FORMATION AND USES THEREOF HDGF, HGF, FGF2 LPAR2 234/4885LPAR3 236/4885
US-20110015280-A1 AMPHOLYTIC COPOLYMER, PRODUCTION THEREOF, AND USE OF THE SAME ABHD16A, ABHD6, IDUA LPAR2 431/4885LPAR3 193/4885
US-20180208635-A1 COMPOUNDS FOR INDUCING TISSUE FORMATION AND USES THEREOF HDGF, HGF, BMP4 LPAR2 395/4885LPAR3 379/4885
US-20090041813-A1 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER NOS1, NOS3, NPSR1 LPAR2 3381/4885LPAR3 1973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.