Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140188 | 0.93 | RAB9A (0.38) | TRPV1KMT2AL3MBTL1PPARGRAB9A | |
| SCHEMBL782242 | 0.92 | MALT1 (0.38) | TRPV1KMT2ANTRK1EPHX2MALT1 | |
| SCHEMBL10140197 | 0.91 | DHODH (0.41) | TRPV1KMT2AL3MBTL1PPARGRAB9A | |
| SCHEMBL10140225 | 0.90 | CNR1 (0.37) | TRPV1KMT2AL3MBTL1RAB9ANPC1 | |
| SCHEMBL782485 | 0.89 | MALT1 (0.39) | TRPV1KMT2ARAB9ANPC1NTRK1 | |
| SCHEMBL10140216 | 0.88 | PDE4B (0.37) | KMT2AMALT1 | |
| SCHEMBL13442911 | 0.88 | PKM (0.35) | TRPV1KMT2APPARGMALT1DHODH | |
| SCHEMBL10140154 | 0.86 | SORT1 (0.39) | TRPV1KMT2AL3MBTL1RAB9ANPC1 | |
| SCHEMBL12528237 | 0.85 | NTRK1 (0.39) | KMT2ARAB9ANPC1NTRK1MALT1 | |
| SCHEMBL10140180 | 0.84 | DHODH (0.40) | TRPV1KMT2AL3MBTL1PPARGRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9949482-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, LLC (US) | 2018-04-24 | — | — | US | disclosed |
| US-20170071205-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, LLC (US) | 2017-03-16 | — | — | US | disclosed |
| US-20160302414-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2016-10-20 | — | — | US | disclosed |
| US-9282743-B2 | Chemical compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-15 | — | — | US | disclosed |
| US-9096525-B2 | Iminipyridine derivatives and their uses as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140148339-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-29 | — | — | US | disclosed |
| US-8536089-B2 | For controlling phytopathogenic diseases; synergistic | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-17 | — | — | US | disclosed |
| US-20130210625-A1 | SPIROHETEROCYCLIC PYRROLIDINE DERIVATIVES BASED PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-15 | — | — | US | disclosed |
| US-20120309812-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-06 | — | — | US | disclosed |
| US-8124566-B2 | Synergistic fungicidal compositions | SYNGENTA CROP PROTECTION, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-8124567-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20080076664-A1 | Fungicidal Compositions | SYNGENTA CROP PROTECTION, INC. | 2008-03-27 | — | — | US | disclosed |
| US-20080070785-A1 | For controlling phytopathogenic diseases; synergistic | SYNGENTA CROP PROTECTION, INC. (US) | 2008-03-20 | — | — | US | disclosed |
| US-20070265267-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, INC. (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070244121-A1 | Synergistic Fungicidal Compositions | SYNGENTA CROP PROTECTION, INC. (US) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309812-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, NISCH | TRPV1 432/4885KMT2A 1531/4885L3MBTL1 772/4885 |
| US-20130210625-A1 | SPIROHETEROCYCLIC PYRROLIDINE DERIVATIVES BASED PESTICIDES | DDT, PYCR1, PKD2 | TRPV1 295/4885KMT2A 3529/4885L3MBTL1 2524/4885 |
| US-20160302414-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, CASP3 | TRPV1 1248/4885KMT2A 3045/4885L3MBTL1 1177/4885 |
| US-20070265267-A1 | FUNGICIDAL COMPOSITIONS | CRY1, ERG28, DDT | TRPV1 1660/4885KMT2A 1397/4885L3MBTL1 247/4885 |
| US-20070244121-A1 | Synergistic Fungicidal Compositions | DDT, CRY1, HCN1 | TRPV1 1081/4885KMT2A 2009/4885L3MBTL1 375/4885 |
| US-20080070785-A1 | For controlling phytopathogenic diseases; synergistic | BROX, EPM2A, MANBA | TRPV1 3772/4885KMT2A 3493/4885L3MBTL1 1584/4885 |
| US-20140148339-A1 | CHEMICAL COMPOUNDS | DDT, CYP1B1, CYP1A1 | TRPV1 347/4885KMT2A 1487/4885L3MBTL1 2310/4885 |
| US-20170071205-A1 | FUNGICIDAL COMPOSITIONS | PIK3C3, CYP51A1, CYP1B1 | TRPV1 2857/4885KMT2A 2404/4885L3MBTL1 2580/4885 |
| US-20080076664-A1 | Fungicidal Compositions | AKR7A2, CYP51A1, TUBA3C | TRPV1 2728/4885KMT2A 3265/4885L3MBTL1 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.