SCHEMBL10140180

SCHEMBL10140180

CNC(=O)c1cc(Cl)cc(C)c1NC(=O)c1cc(Br)nn1-c1ncccc1C

nearest known ligand 0.88

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 2/20 0.40
RAB9A P51151 4/20 0.36
NPC1 O15118 2/20 0.36
TRPV1 Q8NER1 1/20 0.36
SORT1 Q99523 1/20 0.35
KMT2A Q03164 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
F10 P00742 1/20 0.35
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GRM4 Q14833 1/20 0.33
PPARG P37231 1/20 0.33
MALT1 Q9UDY8 1/20 0.33
DRD4 P21917 1/20 0.33
MEN1 O00255 1/20 0.33
NTRK1 P04629 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorantraniliprole SCHEMBL29363261 0.94 DHODH (0.44) DHODHRAB9ANPC1TRPV1F10
Chlorantraniliprole SCHEMBL29551 0.94 DHODH (0.44) DHODHRAB9ANPC1TRPV1F10
SCHEMBL10140197 0.94 DHODH (0.41) DHODHRAB9ANPC1TRPV1SORT1
SCHEMBL10140188 0.90 RAB9A (0.38) RAB9ANPC1TRPV1KMT2AL3MBTL1
SCHEMBL10140148 0.90 SORT1 (0.41) DHODHRAB9ANPC1TRPV1SORT1
SCHEMBL10140172 0.90 DHODH (0.38) DHODHRAB9ANPC1TRPV1SORT1
SCHEMBL12912066 0.87 DHODH (0.44) DHODHRAB9ANPC1TRPV1F10
SCHEMBL10140229 0.86 DHODH (0.37) DHODHRAB9ANPC1SORT1KMT2A
SCHEMBL2396376 0.86 DHODH (0.43) DHODHRAB9ANPC1TRPV1KMT2A
SCHEMBL11891970 0.86 DHODH (0.35) DHODHRAB9ANPC1SORT1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9949482-B2 Fungicidal compositions SYNGENTA CROP PROTECTION, LLC (US) 2018-04-24 US disclosed
EP-2587921-B1 SYNERGISTIC FUNGICIDAL COMBINATIONS CONTAINING PENFLUFEN BAYER IP GMBH (DE) 2018-02-07 EP disclosed
US-20170202220-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, LLC (US) 2017-07-20 US disclosed
US-9642365-B2 Fungicidal compositions SYNGENTA CROP PROTECTION, LLC (US) 2017-05-09 US disclosed
US-20170071205-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, LLC (US) 2017-03-16 US disclosed
US-9538755-B2 Fungicidal compositions SYNGENTA CROP PROTECTION, LLC (US) 2017-01-10 US disclosed
US-20160302414-A1 INSECTICIDAL COMPOUNDS SYNGENTA CROP PROTECTION LLC (US) 2016-10-20 US disclosed
US-9445593-B1 Arthropodicidal anthranilamides E I DU PONT DE NEMOURS AND COMPANY (US) 2016-09-20 US disclosed
US-20160255835-A1 ARTHROPODICIDAL ANTHRANILAMIDES FMC CORPORATION 2016-09-08 US disclosed
US-20160192655-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, LLC (US) 2016-07-07 US disclosed
US-20110142802-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, INC. (US) 2011-06-16 US disclosed
US-20100216640-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, INC. (US) 2010-08-26 US disclosed
US-20100029479-A1 PESTICIDAL COMBINATIONS SYNGENTA CROP PROTECTION, INC. (US) 2010-02-04 US disclosed
EP-2060182-A1 Synergistic mixtures of anthranilamide invertebrate pest control agents E. I. du Pont de Nemours and Company (US) 2009-05-20 EP disclosed
US-20090124499-A1 ENHANCED FORMULATIONS SYNGENTA CROP PROTECTION, INC. (US) 2009-05-14 US disclosed
US-20080206345-A1 Abamectin, lambda-cyhalothrin and lufenuron; nematocides SYNGENTA CROP PROTECTION, INC. (US) 2008-08-28 US disclosed
US-20080076664-A1 Fungicidal Compositions SYNGENTA CROP PROTECTION, INC. 2008-03-27 US disclosed
US-20080070785-A1 For controlling phytopathogenic diseases; synergistic SYNGENTA CROP PROTECTION, INC. (US) 2008-03-20 US disclosed
US-20070265267-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, INC. (US) 2007-11-15 US disclosed
US-20070244121-A1 Synergistic Fungicidal Compositions SYNGENTA CROP PROTECTION, INC. (US) 2007-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080206345-A1 Abamectin, lambda-cyhalothrin and lufenuron; nematocides ATL3, RPL30, MLN DHODH 2123/4885RAB9A 1901/4885NPC1 2980/4885
US-20090124499-A1 ENHANCED FORMULATIONS DDT, CYP3A43, PFAS DHODH 842/4885RAB9A 3964/4885NPC1 3560/4885
US-20110142802-A1 FUNGICIDAL COMPOSITIONS CYP4X1, CYP1B1, CYP4B1 DHODH 834/4885RAB9A 3038/4885NPC1 1465/4885
US-20160192655-A1 FUNGICIDAL COMPOSITIONS BROX, RER1, BLVRB DHODH 677/4885RAB9A 649/4885NPC1 474/4885
US-20100216640-A1 FUNGICIDAL COMPOSITIONS BROX, RER1, BLVRB DHODH 866/4885RAB9A 533/4885NPC1 467/4885
US-20160302414-A1 INSECTICIDAL COMPOUNDS ACHE, AADAC, CASP3 DHODH 1693/4885RAB9A 206/4885NPC1 936/4885
US-20100029479-A1 PESTICIDAL COMBINATIONS DDT, TRHDE, TH DHODH 1607/4885RAB9A 4483/4885NPC1 4670/4885
US-20170202220-A1 FUNGICIDAL COMPOSITIONS BROX, RER1, BLVRB DHODH 677/4885RAB9A 649/4885NPC1 474/4885
US-20070265267-A1 FUNGICIDAL COMPOSITIONS CRY1, ERG28, DDT DHODH 2433/4885RAB9A 1849/4885NPC1 853/4885
US-20070244121-A1 Synergistic Fungicidal Compositions DDT, CRY1, HCN1 DHODH 1980/4885RAB9A 2590/4885NPC1 1049/4885
US-20080070785-A1 For controlling phytopathogenic diseases; synergistic BROX, EPM2A, MANBA DHODH 2383/4885RAB9A 1181/4885NPC1 571/4885
US-20160255835-A1 ARTHROPODICIDAL ANTHRANILAMIDES ANTXR2, NIT2, NAAA DHODH 1137/4885RAB9A 703/4885NPC1 4398/4885
US-20170071205-A1 FUNGICIDAL COMPOSITIONS PIK3C3, CYP51A1, CYP1B1 DHODH 874/4885RAB9A 2585/4885NPC1 1384/4885
US-20080076664-A1 Fungicidal Compositions AKR7A2, CYP51A1, TUBA3C DHODH 717/4885RAB9A 1424/4885NPC1 91/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.