Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15017876 | 1.00 | — | — | |
| SCHEMBL83146 | 0.94 | — | — | |
| SCHEMBL13279167 | 0.89 | — | — | |
| Water SCHEMBL28193772 | 0.89 | — | — | |
| SCHEMBL23701320 | 0.67 | — | — | |
| SCHEMBL2103063 | 0.67 | — | — | |
| SCHEMBL31248588 | 0.67 | — | — | |
| SCHEMBL2272246 | 0.67 | — | — | |
| Isobutane SCHEMBL7892960 | 0.60 | — | — | |
| Isobutane SCHEMBL23045674 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206461-B8 | Process for the preparation of a paclitaxel c-4 methyl carbonate analog | BRISTOL MYERS SQUIBB CO (US) | 2004-07-21 | — | — | EP | claimed |
| EP-1206461-B1 | Process for the preparation of a paclitaxel c-4 methyl carbonate analog | BRISTOL MYERS SQUIBB CO (US) | 2004-05-06 | — | — | EP | claimed |
| EP-1391459-A1 | Process for the preparation of a paclitaxel C-4 methyl carbonate analog and intermediates | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-02-25 | — | — | EP | claimed |
| EP-1206461-A4 | PROCESS FOR THE PREPARATION OF A PACLITAXEL C-4 METHYL CARBONATE ANALOG | BRISTOL MYERS SQUIBB CO (US) | 2003-03-26 | — | — | EP | claimed |
| EP-1206461-A1 | Process for the preparation of a paclitaxel c-4 methyl carbonate analog | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-05-22 | — | — | EP | claimed |
| WO-2001010856-A1 | PROCESS FOR THE PREPARATION OF A PACLITAXEL C-4 METHYL CARBONATE ANALOG | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-02-15 | — | — | WO | claimed |
| CN-102791750-B | Ethylene-alpha-olefin copolymer and molded article | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2014-10-29 | — | — | CN | disclosed |
| CN-102459365-B | Ethylene/alpha-olefin copolymer and moldings | SUMITOMO CHEMICAL CO | 2013-08-21 | — | — | CN | disclosed |
| CN-102791750-A | Ethylene-alpha-olefin copolymer and molded article | SUMITOMO CHEMICAL CO | 2012-11-21 | — | — | CN | disclosed |
| CN-102459365-A | Ethylene-alpha-olefin copolymer and molded article | SUMITOMO CHEMICAL CO | 2012-05-16 | — | — | CN | disclosed |
| CN-102459366-A | Ethylene-alpha-olefin copolymer and molded article | SUMITOMO CHEMICAL CO | 2012-05-16 | — | — | CN | disclosed |
| CN-102459367-A | Ethylene-alpha-olefin copolymer, molded article, catalyst for copolymerization, and process for producing ethylene-alpha-olefin copolymer | SUMITOMO CHEMICAL CO | 2012-05-16 | — | — | CN | disclosed |
| EP-1229020-B1 | TRANSITION METAL COMPOUND, OLEFIN POLYMERIZATION CATALYST, AND METHOD OF POLYMERIZING OLEFIN | IDEMITSU KOSAN CO (JP) | 2011-01-19 | — | — | EP | disclosed |
| EP-1066877-A1 | CATALYSTS FOR $g(a)-OLEFIN PRODUCTION AND PROCESSES FOR PRODUCING $g(a)-OLEFIN | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |
| EP-1054021-A1 | CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE CATALYST | Idemitsu Petrochemical Co., Ltd. (JP) | 2000-11-22 | — | — | EP | disclosed |
| EP-1026176-A1 | CATALYST FOR OLEFIN POLYMER PRODUCTION, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING OLEFIN POLYMER | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2000-08-09 | — | — | EP | disclosed |
| EP-1010008-A2 | MASS SPECTROMETRIC DETECTION OF POLYPEPTIDES | SEQUENOM, INC. (US) | 2000-06-21 | — | — | EP | disclosed |
| EP-0985685-A1 | CATALYSTS FOR OLEFIN POLYMER PRODUCTION AND PROCESS FOR PRODUCING OLEFIN POLYMER | Idemitsu Petrochemical Co., Ltd. (JP) | 2000-03-15 | — | — | EP | disclosed |
| EP-0945471-A1 | CATALYSTS FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS, AND PROCESSES FOR THE PRODUCTION OF STYRENE POLYMERS | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |
| WO-1999012040-A2 | MASS SPECTROMETRIC DETECTION OF POLYPEPTIDES | SEQUENOM, INC. (US) | 1999-03-11 | — | — | WO | disclosed |