Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Anthraquinone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA known ✓ | P21397 | 4/20 | 0.65 |
| ▸ | S1PR4 known ✓ | O95977 | 1/20 | 0.65 |
| ▸ | BCHE known ✓ | P06276 | 1/20 | 0.65 |
| ▸ | S1PR1 known ✓ | P21453 | 1/20 | 0.65 |
| ▸ | PPARG known ✓ | P37231 | 1/20 | 0.65 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | CDC25B | P30305 | 2/20 | 0.80 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | APAF1 | O14727 | 2/20 | 0.65 |
| ▸ | TDP2 | O95551 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | S100A4 | P26447 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthraquinone SCHEMBL7915429 | 0.97 | MEN1 (0.86) | MEN1KMT2ACDC25BMAPTMAOA | |
| Nitrogen SCHEMBL28051706 | 0.93 | MEN1 (0.80) | MEN1KMT2ACDC25BMAPTMAOA | |
| Anthraquinone SCHEMBL27684132 | 0.93 | MEN1 (0.92) | MEN1KMT2ACDC25BMAPTMAOA | |
| Anthraquinone SCHEMBL240670 | 0.93 | MEN1 (0.92) | MEN1KMT2ACDC25BMAPTMAOA | |
| Anthraquinone SCHEMBL31072162 | 0.93 | MEN1 (0.92) | MEN1KMT2ACDC25BMAPTMAOA | |
| Anthraquinone SCHEMBL29358690 | 0.89 | MEN1 (1.00) | MEN1KMT2ACDC25BMAPTMAOA | |
| Anthraquinone SCHEMBL14943 | 0.89 | MEN1 (1.00) | MEN1KMT2ACDC25BMAPTMAOA | |
| Anthraquinone SCHEMBL1901249 | 0.89 | MEN1 (1.00) | MEN1KMT2ACDC25BMAPTMAOA | |
| Anthraquinone SCHEMBL939193 | 0.87 | MEN1 (0.80) | MEN1KMT2ACDC25BMAPTMAOA | |
| Anthraquinone SCHEMBL6415478 | 0.86 | MEN1 (0.92) | MEN1KMT2ACDC25BMAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8206570-B2 | Includes electrolysis of a solution containing an adhesion primer in contact with a surface followed by a reaction at the surface obtained, of a solution containing a protic solvent, and a radically polymerizable monomer | COMMISSARIAT A L'ENERGIE ATOMIQUE, ETABLISSEMENT PUBLIC A CARACTERE INDUSTRIEL ET COMMERCIAL (FR) | 2012-06-26 | — | — | US | claimed |
| US-8152986-B2 | Process for forming organic films on electrically conductive or semi-conductive surfaces using aqueous solutions | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2012-04-10 | — | — | US | claimed |
| US-20080087550-A1 | PROCESS FOR FORMING ORGANIC FILMS ON ELECTRICALLY CONDUCTIVE OR SEMI-CONDUCTIVE SURFACES USING AQUEOUS SOLUTIONS IN TWO STEPS | COMMISSARIAT A L' ENERGIE ATOMIQUE, Etablissement Public a caractere Industriel et Commercial (FR) | 2008-04-17 | — | — | US | claimed |
| US-20070289872-A1 | Process for forming organic films on electrically conductive or semi-conductive surfaces using aqueous solutions | COMMISSARIAT A L'ENERGIE ATOMIQUE | 2007-12-20 | — | — | US | claimed |
| US-8206570-B2 | Includes electrolysis of a solution containing an adhesion primer in contact with a surface followed by a reaction at the surface obtained, of a solution containing a protic solvent, and a radically polymerizable monomer | COMMISSARIAT A L'ENERGIE ATOMIQUE, ETABLISSEMENT PUBLIC A CARACTERE INDUSTRIEL ET COMMERCIAL (FR) | 2012-06-26 | — | — | US | disclosed |
| US-8152986-B2 | Process for forming organic films on electrically conductive or semi-conductive surfaces using aqueous solutions | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2012-04-10 | — | — | US | disclosed |
| US-7959773-B2 | Electroactivated film with electrocatalyst-enhanced carbon electrode | LUMIMOVE, INC. (US) | 2011-06-14 | — | — | US | disclosed |
| US-7842637-B2 | Electroactivated film with polymer gel electrolyte | LUMIMOVE, INC. (US) | 2010-11-30 | — | — | US | disclosed |
| US-20090288945-A1 | Electroactivated film with electrocatalyst-enhanced carbon electrode | LUMIMOVE, INC. DBA CROSSLINK (US) | 2009-11-26 | — | — | US | disclosed |
| WO-2009143314-A2 | ELECTROACTIVATED FILM WITH POLYMER GEL ELECTROLYTE | LUMIMOVE, INC., A MISSOURI CORPORATION, DBA CROSSLINK (US) | 2009-11-26 | — | — | WO | disclosed |
| US-20090291843-A1 | Electroactivated film with polymer gel electrolyte | LUMIMOVE, INC. DBA CROSSLINK (US) | 2009-11-26 | — | — | US | disclosed |
| US-20090288946-A1 | Electroactivated film with layered structure | LUMIMOVE, INC. DBA CROSSLINK (US) | 2009-11-26 | — | — | US | disclosed |
| US-20090291844-A1 | Electroactivated film with immobilized peroxide activating catalyst | LUMIMOVE, INC. DBA CROSSLINK (US) | 2009-11-26 | — | — | US | disclosed |
| US-20080087550-A1 | PROCESS FOR FORMING ORGANIC FILMS ON ELECTRICALLY CONDUCTIVE OR SEMI-CONDUCTIVE SURFACES USING AQUEOUS SOLUTIONS IN TWO STEPS | COMMISSARIAT A L' ENERGIE ATOMIQUE, Etablissement Public a caractere Industriel et Commercial (FR) | 2008-04-17 | — | — | US | disclosed |
| US-20070289872-A1 | Process for forming organic films on electrically conductive or semi-conductive surfaces using aqueous solutions | COMMISSARIAT A L'ENERGIE ATOMIQUE | 2007-12-20 | — | — | US | disclosed |