Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.94 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6420004 | 1.00 | F2 (0.94) | F2ALDH1A1CA1CA2CA12 | |
| Hydrochloric Acid SCHEMBL2722649 | 1.00 | F2 (0.94) | F2ALDH1A1CA1CA2CA12 | |
| Hydrochloric Acid SCHEMBL6422667 | 1.00 | F2 (0.94) | F2ALDH1A1CA1CA2CA12 | |
| SCHEMBL11288384 | 0.97 | F2 (1.00) | F2ALDH1A1CA1CA2CA12 | |
| SCHEMBL1228214 | 0.97 | — | — | |
| SCHEMBL11295735 | 0.97 | F2 (1.00) | F2ALDH1A1CA1CA2CA12 | |
| Hydrochloric Acid SCHEMBL3192296 | 0.97 | — | — | |
| SCHEMBL821192 | 0.97 | F2 (1.00) | F2ALDH1A1CA1CA2CA12 | |
| SCHEMBL8281615 | 0.97 | F2 (1.00) | F2ALDH1A1CA1CA2CA12 | |
| SCHEMBL11295249 | 0.97 | F2 (1.00) | F2ALDH1A1CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115399333-A | Preparation method and application of antibacterial nano composite material | 江苏集萃先进纤维材料研究所有限公司 | 2022-11-29 | — | — | CN | claimed |
| CN-115341296-A | Wear-resistant fiber for clothing and preparation method of fabric of wear-resistant fiber | 创姿服饰(上海)有限公司 | 2022-11-15 | — | — | CN | claimed |
| CN-115197493-A | Anti-biological fouling material and preparation method and application thereof | 阳光水面光伏科技有限公司 | 2022-10-18 | — | — | CN | claimed |
| CN-115075012-A | Antifouling net and preparation method and application thereof | 太原理工大学 | 2022-09-20 | — | — | CN | claimed |
| CN-113797385-B | Chitosan/polyethylene glycol hydrogel and preparation method and application thereof | 山东大学 | 2022-05-24 | — | — | CN | claimed |
| CN-111892883-B | Glass explosion-proof adhesive film with antibacterial and mildew-proof effects and preparation method thereof | 湖北航天化学技术研究所 | 2022-04-08 | — | — | CN | claimed |
| CN-110483810-B | Preparation method of nano-cellulose antibacterial hydrogel | 广西大学 | 2022-03-04 | — | — | CN | claimed |
| CN-113981708-A | Washable and durable antibacterial porous breathable silica gel coating and preparation and application thereof | 浪莎针织有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-113907086-A | Environment-friendly efficient composite disinfectant and preparation method thereof | 杨冬 | 2022-01-11 | — | — | CN | claimed |
| CN-113797385-A | Chitosan/polyethylene glycol hydrogel and preparation method and application thereof | 山东大学 | 2021-12-17 | — | — | CN | claimed |
| CN-111184658-A | Hand disinfectant and preparation method thereof | 吉林云飞医药有限公司 | 2020-05-22 | — | — | CN | claimed |
| CN-111175188-A | Method for rapidly detecting average molecular weight of polyhexamethylene guanidine hydrochloride | 刘白玲 | 2020-05-19 | — | — | CN | claimed |
| US-20180249713-A1 | Composition for Protection of Plants, Fruit and Vegetables | LIQUID VANITY APS (DK) | 2018-09-06 | — | — | US | claimed |
| EP-3344038-A1 | COMPOSITION FOR PROTECTION OF PLANTS, FRUIT AND VEGETABLES | Liquid Vanity ApS (DK) | 2018-07-11 | — | — | EP | claimed |
| WO-2017036484-A1 | COMPOSITION FOR PROTECTION OF PLANTS, FRUIT AND VEGETABLES | LIQUID VANITY APS (DK) | 2017-03-09 | — | — | WO | claimed |
| EP-2910124-A1 | STIMULANT AND METHOD FOR STIMULATING PLANT GROWTH AND DEVELOPMENT | Obshchestvo S Ogranichennoy Otvetstvennostyu "Nanobiotekh" (RU) | 2015-08-26 | — | — | EP | claimed |
| WO-2007101445-A1 | BIOCIDAL CLEANING COMPOSITIONS | GLAD, THOMAS CHRISTIAN (DK) | 2007-09-13 | — | — | WO | claimed |
| US-20070071702-A1 | Use of a polyguanidine compound for treating or shaping the hair, especially for straightening or permanent-waving it | PHILIPPE MICHEL | 2007-03-29 | — | — | US | claimed |
| EP-1302194-B1 | Use of a polyguanidine compound for treating or styling hair, especially for straightening or permanent waving | OREAL (FR) | 2006-07-05 | — | — | EP | claimed |
| US-20030133898-A1 | Use of polyguanidine compound for treating or shaping the hair, especially for straightening or permanent-waving it | L'OREAL (FR) | 2003-07-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070071702-A1 | Use of a polyguanidine compound for treating or shaping the hair, especially for straightening or permanent-waving it | KRT18, PTMA, PARG | CA2 2525/4885F2 3011/4885ALDH1A1 2353/4885 |
| US-20030133898-A1 | Use of polyguanidine compound for treating or shaping the hair, especially for straightening or permanent-waving it | KRT18, PTMA, PARG | CA2 2222/4885F2 2746/4885ALDH1A1 2491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.