Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 known ✓ | P54289 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL628625 | 1.00 | CYP2C19 (0.40) | CYP2C19FFAR3AKR1C1CYP2D6NPSR1 | |
| Hydrochloric Acid SCHEMBL3681432 | 0.97 | CYP2C19 (0.44) | CYP2C19FFAR3AKR1C1CYP2D6NPSR1 | |
| Hydrochloric Acid SCHEMBL1188224 | 0.97 | CYP2C19 (0.44) | CYP2C19FFAR3AKR1C1CYP2D6NPSR1 | |
| Hydrochloric Acid SCHEMBL627710 | 0.97 | CYP2C19 (0.44) | CYP2C19FFAR3AKR1C1CYP2D6NPSR1 | |
| SCHEMBL440358 | 0.97 | CYP2C19 (0.42) | CYP2C19FFAR3AKR1C1CYP2D6NPSR1 | |
| SCHEMBL5509416 | 0.93 | CYP2C19 (0.46) | CYP2C19FFAR3AKR1C1CYP2D6NPSR1 | |
| SCHEMBL20679048 | 0.93 | CYP2C19 (0.46) | CYP2C19FFAR3AKR1C1CYP2D6NPSR1 | |
| SCHEMBL21295011 | 0.93 | CYP2C19 (0.40) | CYP2C19FFAR3AKR1C1CYP2D6NPSR1 | |
| Bromide SCHEMBL16086053 | 0.93 | CYP2C19 (0.40) | CYP2C19FFAR3AKR1C1CYP2D6NPSR1 | |
| SCHEMBL466149 | 0.93 | CYP2C19 (0.46) | CYP2C19FFAR3AKR1C1CYP2D6NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119565382-A | Method for cleaning reverse osmosis membrane and reverse osmosis membrane prepared by same | 万华化学集团股份有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-119345927-A | Polyamide composite semipermeable membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2025-01-24 | — | — | CN | claimed |
| US-20230330604-A1 | MOLECULARLY POROUS CROSS-LINKED MEMBRANES | UNIV KING ABDULLAH SCI & TECH (SA) | 2023-10-19 | — | — | US | claimed |
| CN-112827368-B | Anti-pollution reverse osmosis membrane and preparation method thereof | 中化(宁波)润沃膜科技有限公司 | 2023-08-11 | — | — | CN | claimed |
| CN-116351258-A | Preparation method and application of anti-pollution polyamide composite membrane | 万华化学集团股份有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-113600040-B | High-flux polyethylene-based reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-114053876-B | Preparation method of anti-pollution reverse osmosis membrane | 万华化学集团股份有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-115845615-A | High-flux polyethylene-based reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-112870989-B | Anti-pollution composite reverse osmosis membrane and preparation method thereof | 中化(宁波)润沃膜科技有限公司 | 2023-03-17 | — | — | CN | claimed |
| CN-115228290-A | Preparation method of cleaning-resistant reverse osmosis membrane | 万华化学集团股份有限公司 | 2022-10-25 | — | — | CN | claimed |
| CN-114749038-A | High-flux reverse osmosis composite membrane and preparation method thereof | 中化(宁波)润沃膜科技有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-111715083-B | Modified polyamide desalting layer, reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-04-12 | — | — | CN | claimed |
| WO-2022058961-A1 | MOLECULARLY POROUS CROSS-LINKED MEMBRANES | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2022-03-24 | — | — | WO | claimed |
| CN-114053876-A | Preparation method of anti-pollution reverse osmosis membrane | 万华化学集团股份有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-113600040-A | High-flux polyethylene-based reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2021-11-05 | — | — | CN | claimed |
| CN-112870989-A | Anti-pollution composite reverse osmosis membrane and preparation method thereof | 中化(宁波)润沃膜科技有限公司 | 2021-06-01 | — | — | CN | claimed |
| CN-112827368-A | Anti-pollution reverse osmosis membrane and preparation method thereof | 中化(宁波)润沃膜科技有限公司 | 2021-05-25 | — | — | CN | claimed |
| US-20160263530-A1 | FABRICATION AND MODIFICATION OF POLYMER MEMBRANES USING INK-JET PRINTING | B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD (IL) | 2016-09-15 | — | — | US | claimed |
| EP-1020218-B1 | COMPOSITE REVERSE OSMOSIS MEMBRANE AND PROCESS FOR PREPARING THE SAME | NITTO DENKO CORP (JP) | 2003-05-21 | — | — | EP | claimed |
| EP-1020218-A1 | COMPOSITE REVERSE OSMOSIS MEMBRANE AND PROCESS FOR PREPARING THE SAME | NITTO DENKO CORPORATION (JP) | 2000-07-19 | — | — | EP | claimed |