SCHEMBL124132

SCHEMBL124132

O=S(=O)([O-])c1cc(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c1.[Na+].[Na+].[Na+]

nearest known ligand 0.54

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 known ✓ P00915 1/20 0.35
CA2 known ✓ P00918 1/20 0.35
PTGS1 known ✓ P23219 1/20 0.32
DUSP5 Q16690 4/20 0.54
PTPN1 P18031 3/20 0.54
DUSP6 Q16828 1/20 0.54
LMNA P02545 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
PKLR P30613 2/20 0.41
SIRT1 Q96EB6 1/20 0.37
PRMT1 Q99873 1/20 0.37
KMT2A Q03164 5/20 0.35
MEN1 O00255 3/20 0.35
POLB P06746 2/20 0.35
APOBEC3A P31941 1/20 0.35
CASP6 P55212 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216137 0.93 PTPN1 (0.50) DUSP5PTPN1DUSP6LMNATDP1
Silver SCHEMBL216135 0.93 PTPN1 (0.50) DUSP5PTPN1DUSP6LMNATDP1
Potassium Ion SCHEMBL9220931 0.93 PTPN1 (0.50) DUSP5PTPN1DUSP6LMNATDP1
SCHEMBL10893549 0.86 DUSP5 (0.45) DUSP5PTPN1DUSP6LMNATDP1
SCHEMBL26691693 0.86 DUSP5 (0.56) DUSP5PTPN1DUSP6LMNATDP1
SCHEMBL128235 0.82 LMNA (0.56) DUSP5PTPN1DUSP6LMNATDP1
SCHEMBL6520074 0.82 DUSP5 (0.42) DUSP5PTPN1DUSP6LMNATDP1
SCHEMBL19953365 0.81 LMNA (0.55) DUSP5PTPN1DUSP6LMNATDP1
SCHEMBL11221351 0.80 HTT (0.48) DUSP5PTPN1DUSP6LMNAKMT2A
SCHEMBL10597407 0.80 LCK (0.56) DUSP5PTPN1DUSP6LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12146184-B2 Blood glucose measurement reagent, sensor chip, and blood glucose meter set TERUMO KABUSHIKI KAISHA (JP) 2024-11-19 US disclosed
CN-111788472-B Method, reagent and chip for determining concentration of analyte in biological sample 泰尔茂株式会社 2023-12-15 CN disclosed
US-11815448-B2 Method, reagent, and chip for measuring analyte concentration in specimen TERUMO KABUSHIKI KAISHA (JP) 2023-11-14 US disclosed
US-11719701-B2 Blood glucose level measuring chip and blood glucose level measuring device set TERUMO KABUSHIKI KAISHA (JP) 2023-08-08 US disclosed
CN-110291185-B Blood sugar level measurement chip and blood sugar level measurement device set 泰尔茂株式会社 2022-08-09 CN disclosed
CN-108368472-B Blood sugar level measuring reagent, blood sugar level measuring chip, and blood sugar level measuring apparatus set 泰尔茂株式会社 2021-09-21 CN disclosed
US-20200371020-A1 METHOD, REAGENT, AND CHIP FOR MEASURING ANALYTE CONCENTRATION IN SPECIMEN TERUMO KABUSHIKI KAISHA (JP) 2020-11-26 US disclosed
EP-3736571-A1 METHOD, REAGENT, AND CHIP, FOR MEASURING ANALYTE CONCENTRATION IN BIOLOGICAL SAMPLE TERUMO KABUSHIKI KAISHA (JP) 2020-11-11 EP disclosed
CN-111788472-A Method, reagent and chip for determining concentration of analyte in biological sample 泰尔茂株式会社 2020-10-16 CN disclosed
EP-2006738-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2017-09-06 EP disclosed
EP-2006738-A2 Lithographic printing plate precursor and lithographic printing method Fujifilm Corporation (JP) 2008-12-24 EP disclosed
US-20080286685-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
EP-1992482-A2 Planographic printing plate precursor and printing method using the same FUJIFILM Corporation (JP) 2008-11-19 EP disclosed
US-20070214987-A1 Lithographic printing plate precursor FUJIFILM CORPORATION 2007-09-20 US disclosed
EP-1834766-A2 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2007-09-19 EP disclosed
US-20040010028-A1 Self-assembled nanostructures with macroscopic polar order TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE 2004-01-15 US disclosed
WO-2002044124-A9 SELF-ASSEMBLED NANOSTRUCTURES WITH MACROSCOPIC POLAR ORDER UNIV COLUMBIA (US) 2003-11-13 WO disclosed
WO-2002044124-A2 SELF-ASSEMBLED NANOSTRUCTURES WITH MACROSCOPIC POLAR ORDER THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2002-06-06 WO disclosed
US-5378550-A Electrolytes for power sources THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1995-01-03 US disclosed
EP-0421660-A2 Improvements to electrical cells Ever Ready Limited (GB) 1991-04-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200371020-A1 METHOD, REAGENT, AND CHIP FOR MEASURING ANALYTE CONCENTRATION IN SPECIMEN STUB1, MPO, ALDH1A2 CA1 2095/4885CA2 3576/4885PTGS1 4002/4885
US-11815448-B2 Method, reagent, and chip for measuring analyte concentration in specimen STUB1, MPO, ALDH1A2 CA1 2095/4885CA2 3576/4885PTGS1 4002/4885
US-20040010028-A1 Self-assembled nanostructures with macroscopic polar order PIEZO1, PYM1, KCNH1 CA1 1227/4885CA2 1391/4885PTGS1 4535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.