Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL367050 | 1.00 | TSHR (0.75) | — | |
| Pyridine SCHEMBL1895575 | 0.96 | — | — | |
| Benzene SCHEMBL28210123 | 0.96 | TSHR (0.82) | — | |
| Pyridine SCHEMBL28470067 | 0.96 | TSHR (0.82) | — | |
| Pyridine SCHEMBL6115211 | 0.96 | TSHR (0.82) | — | |
| Pyridine SCHEMBL27791776 | 0.96 | TSHR (0.82) | — | |
| Pyridine SCHEMBL11877627 | 0.96 | TSHR (0.82) | — | |
| Pyridine SCHEMBL23877918 | 0.92 | TSHR (0.75) | — | |
| Pyridine SCHEMBL28572430 | 0.92 | TSHR (0.75) | — | |
| Pyridine SCHEMBL10978290 | 0.92 | TSHR (0.75) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103509180-B | Polymeric dispersions and the method preparing polymeric dispersions | AKZO NOBEL N. V. (NL) | 2015-12-09 | — | — | CN | disclosed |
| CN-102666376-B | Process for production of carbon microparticle | TORAY INDUSTRIES | 2015-05-13 | — | — | CN | disclosed |
| CN-103509180-A | Polymer dispersion and process for preparing a polymer dispersion | AKZO NOBEL NV | 2014-01-15 | — | — | CN | disclosed |
| CN-102666376-A | Carbon microparticle and process for production thereof | TORAY INDUSTRIES | 2012-09-12 | — | — | CN | disclosed |
| CN-102448447-A | Drug delivery compositions | ELAN PHARMA INT LTD | 2012-05-09 | — | — | CN | disclosed |
| US-20110266681-A1 | ELECTRONIC COMPONENT AS WELL AS METHOD FOR ITS PRODUCTION | ROBERT BOSCH GMBH (DE) | 2011-11-03 | — | — | US | disclosed |
| CN-101443018-A | Sterilized nanoparticulate glucocorticosteroid formulations | ELAN PHARMA INT LTD (IE) | 2009-05-27 | — | — | CN | disclosed |
| CN-101426477-A | Nanoparticulate carvedilol formulations | ELAN PHARMA INT LTD (IE) | 2009-05-06 | — | — | CN | disclosed |
| CN-101242810-A | Nanoparticulate megestrol formulations | ELAN PHARMA INT LTD (IE) | 2008-08-13 | — | — | CN | disclosed |
| CN-101198316-A | Nanoparticulate bisphosphonate compositions | ELAN PHARMA INT LTD (IE) | 2008-06-11 | — | — | CN | disclosed |
| CN-101175481-A | Injectable compositions of nanoparticulate immunosuppressive compounds | ELAN PHARMA INT LTD (IE) | 2008-05-07 | — | — | CN | disclosed |
| CN-101175480-A | Nanoparticulate leukotriene receptor antagonist/corticosteroid formulations | ELAN PHARMA INT LTD (IE) | 2008-05-07 | — | — | CN | disclosed |
| CN-101132768-A | Nanoparticulate tacrolimus formulations | ELAN PHARMA INT LTD (IE) | 2008-02-27 | — | — | CN | disclosed |
| CN-101094881-A | Polymer dispersion and method for producing a polymer dispersion | AKZO NOBEL NV (NL) | 2007-12-26 | — | — | CN | disclosed |
| CN-1137923-C | Silicon-containing block-copolymer | ������ҩ��ҵ��ʽ���� | 2004-02-11 | — | — | CN | disclosed |
| CN-1157834-A | Silicon-containing block-copolymer | WAKO PURE CHEM IND LTD (JP) | 1997-08-27 | — | — | CN | disclosed |