Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2248708 | 0.95 | — | — | |
| SCHEMBL38271 | 0.89 | — | — | |
| SCHEMBL7650847 | 0.84 | — | — | |
| SCHEMBL2357940 | 0.84 | — | — | |
| SCHEMBL1309134 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL28273513 | 0.64 | — | — | |
| SCHEMBL14615982 | 0.64 | — | — | |
| Diethylamine SCHEMBL124914 | 0.63 | — | — | |
| Diethylamine SCHEMBL5321340 | 0.63 | — | — | |
| Diethylamine SCHEMBL2869417 | 0.63 | TP53 (0.89) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8709153-B2 | Microfludic protein crystallography techniques | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-04-29 | — | — | US | disclosed |
| US-20140041727-A1 | HIGH THROUGHPUT SCREENING OF CRYSTALLIZATION OF MATERIALS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-02-13 | — | — | US | disclosed |
| US-8382896-B2 | High throughput screening of crystallization materials | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-02-26 | — | — | US | disclosed |
| US-20120241015-A1 | Microfluidic Protein Crystallography Techniques | NATIONAL INSTITUTES OF HEALTH | 2012-09-27 | — | — | US | disclosed |
| US-20110306522-A1 | MICROFLUIDIC PROTEIN CRYSTALLOGRAPHY | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2011-12-15 | — | — | US | disclosed |
| US-8052792-B2 | Microfluidic protein crystallography techniques | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2011-11-08 | — | — | US | disclosed |
| US-7927422-B2 | Microfluidic protein crystallography | NATIONAL INSTITUTES OF HEALTH (NIH) (US) | 2011-04-19 | — | — | US | disclosed |
| US-20090168066-A1 | MICROFLUIDIC PROTEIN CRYSTALLOGRAPHY | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2009-07-02 | — | — | US | disclosed |
| US-7459022-B2 | Microfluidic protein crystallography | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-12-02 | — | — | US | disclosed |
| US-7279146-B2 | Crystal growth devices and systems, and methods for using same | FLUIDIGM CORPORATION (US) | 2007-10-09 | — | — | US | disclosed |
| US-20070209574-A1 | MICROFLUIDIC PROTEIN CRYSTALLOGRAPHY TECHNIQUES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-09-13 | — | — | US | disclosed |
| US-20070209572-A1 | HIGH THROUGHPUT SCREENING OF CRYSTALLIZATION MATERIALS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-09-13 | — | — | US | disclosed |
| US-7244402-B2 | Microfluidic protein crystallography | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-07-17 | — | — | US | disclosed |
| US-7217321-B2 | Microfluidic protein crystallography techniques | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-05-15 | — | — | US | disclosed |
| US-7195670-B2 | High throughput screening of crystallization of materials | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-03-27 | — | — | US | disclosed |
| US-20050205005-A1 | Microfluidic protein crystallography | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2005-09-22 | — | — | US | disclosed |
| US-20050062196-A1 | Microfluidic protein crystallography techniques | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2005-03-24 | — | — | US | disclosed |
| US-20050019794-A1 | Crystal growth devices and systems, and methods for using same | FLUIDIGM CORPORATION (US) | 2005-01-27 | — | — | US | disclosed |
| US-20040115731-A1 | Microfluidic protein crystallography | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2004-06-17 | — | — | US | disclosed |
| US-20030061687-A1 | High throughput screening of crystallization materials | CALIFORNIA INSTITUTE OF TECHNOLOGY, A CALIFORNIA CORPORATION | 2003-04-03 | — | — | US | disclosed |