Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28562796 | 1.00 | TSHR (0.45) | TSHRALDH1A1TDP1THRBSLC7A5 | |
| Hydrochloric Acid SCHEMBL6276657 | 0.98 | TSHR (0.43) | TSHRALDH1A1TDP1THRBSLC7A5 | |
| SCHEMBL111244 | 0.98 | — | — | |
| Bromide SCHEMBL4441945 | 0.95 | TSHR (0.45) | TSHRALDH1A1TDP1THRBSLC7A5 | |
| Ammonia Solution, Strong SCHEMBL22612066 | 0.95 | TSHR (0.45) | TSHRALDH1A1TDP1THRBSLC7A5 | |
| Trimethylammonium SCHEMBL27603507 | 0.94 | TSHR (0.41) | TSHRALDH1A1TDP1THRBSLC7A5 | |
| Acetic Acid SCHEMBL10585011 | 0.93 | TSHR (0.43) | TSHRALDH1A1TDP1THRBSLC7A5 | |
| Chloromethane SCHEMBL5583237 | 0.93 | TSHR (0.43) | TSHRALDH1A1TDP1THRBSLC7A5 | |
| Methacrylic Acid SCHEMBL27492294 | 0.91 | TSHR (0.42) | TSHRALDH1A1TDP1THRBSLC7A5 | |
| Propane SCHEMBL29190806 | 0.91 | TSHR (0.47) | TSHRALDH1A1TDP1THRBSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12633521-B2 | Silicon nanoparticles and methods for preparing silicon nanoparticles | ASPEN AEROGELS, INC. (US) | 2026-05-19 | — | — | US | claimed |
| CN-120136114-A | Preparation method of non-spherical ultra-high purity silicon dioxide | 万华化学集团股份有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-119390890-A | Cationic flocculant and preparation method and application thereof | 中国海洋石油集团有限公司 | 2025-02-07 | — | — | CN | claimed |
| CN-118620301-A | High-temperature-resistant flame-retardant cable material and preparation method thereof | 常州工业职业技术学院 | 2024-09-10 | — | — | CN | claimed |
| US-20240274795-A1 | SILICON NANOPARTICLES AND METHODS FOR PREPARING SILICON NANOPARTICLES | ASPEN AEROGELS, INC. (US) | 2024-08-15 | — | — | US | claimed |
| US-11978890-B2 | Silicon nanoparticles and methods for preparing silicon nanoparticles | ASPEN AEROGELS, INC. (US) | 2024-05-07 | — | — | US | claimed |
| CN-117990906-A | Thrombin-antithrombin complex assay reagent and assay method | 普和希株式会社 | 2024-05-07 | — | — | CN | claimed |
| CN-116874680-A | Emulsion type silicone oil modified polyacrylamide and preparation method and application thereof | 杭州传化精细化工有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-116590938-A | Polyester cotton dispersion activity short-process dyeing process | 浙江红绿蓝纺织印染有限公司 | 2023-08-15 | — | — | CN | claimed |
| EP-4200253-A2 | SILICON NANOPARTICLES AND METHODS TO DEAGGLOMERATE SILICON INTO SILICON NANOPARTICLES | Aspen Aerogels Inc. (US) | 2023-06-28 | — | — | EP | claimed |
| CN-103193675-A | Method for preparing ethyl methacrylate isocyanate | ZHEJIANG TONGFENG PHARMACEUTICAL & CHEMICAL CO LTD | 2013-07-10 | — | — | CN | claimed |
| CN-101370453-A | Compositions and methods for dermal delivery of drugs | ZARS PHARMA INC (US) | 2009-02-18 | — | — | CN | claimed |
| EP-1046037-B1 | IMPROVED MAGNETIC PARTICLES, METHOD FOR OBTAINING SAME AND USES FOR SEPARATING MOLECULES | BIO MERIEUX (FR) | 2005-05-11 | — | — | EP | claimed |
| CN-1257512-A | Preparation of water soluble polymer dispersions from vinylamide monomers | NALCO CHEMICAL CO (US) | 2000-06-21 | — | — | CN | claimed |
| EP-0213896-B1 | ADHESION PROMOTING POLYMERIC MATERIALS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1992-01-22 | — | — | EP | claimed |
| EP-0213317-B1 | BASE-CATALYZED, LOW TEMPERATURE SELF-CROSSLINKING POLYMERS | National Starch and Chemical Investment Holding Corporation (US) | 1991-12-04 | — | — | EP | claimed |
| US-4788267-A | CONTAINING HALOHYDRIN MONOMER AND AMINE SALT MONOMER | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1988-11-29 | — | — | US | claimed |
| US-4689359-A | SUBBING LAYERS FOR PHOTOGRAPHIC FILM SUPPORTS; ADHESION | EASTMAN KODAK COMPANY (US) | 1987-08-25 | — | — | US | claimed |
| EP-0213317-A2 | Base-catalyzed, low temperature self-crosslinking polymers | National Starch and Chemical Investment Holding Corporation (US) | 1987-03-11 | — | — | EP | claimed |
| EP-0213896-A2 | Adhesion promoting polymeric materials | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1987-03-11 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12633521-B2 | Silicon nanoparticles and methods for preparing silicon nanoparticles | SIK3, SIK2, SGK3 | TSHR 2063/4885ALDH1A1 3476/4885TDP1 4024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.