Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27632540 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL2401664 | 1.00 | — | — | |
| SCHEMBL28555659 | 0.95 | CTSA (0.33) | — | |
| SCHEMBL446987 | 0.95 | — | — | |
| Iodide SCHEMBL28752893 | 0.90 | — | — | |
| Bromide SCHEMBL27670404 | 0.90 | — | — | |
| SCHEMBL30020425 | 0.90 | — | — | |
| Bromide SCHEMBL11129901 | 0.90 | — | — | |
| SCHEMBL1960466 | 0.79 | — | — | |
| SCHEMBL901487 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632752-B | A kind of olefine polymerizing process | 营口风光新材料股份有限公司 | 2019-04-02 | — | — | CN | claimed |
| CN-107129440-B | A kind of total synthesis method of natural products (+)-negamycin | 上海应用技术大学 | 2018-12-04 | — | — | CN | claimed |
| CN-108854591-A | It is a kind of using tannic acid-titanium as composite nanometer filtering film of separating layer and preparation method thereof | 厦门理工学院 | 2018-11-23 | — | — | CN | claimed |
| CN-108822048-A | The synthesis technology of 4- (- 4,7 diazaspiracyclic of 4- ethyl [3,3] octyl) -2- nitroaniline | 上海昌肽生物科技有限公司 | 2018-11-16 | — | — | CN | claimed |
| CN-104829756-B | A kind of solid catalyst component for olefine polymerization and its preparation method and application | 中国科学院化学研究所 | 2018-05-15 | — | — | CN | claimed |
| CN-104829757-B | A kind of ingredient of solid catalyst of olefin polymerization acid esters compound containing bigcatkin willow and its preparation method and application | 中国科学院化学研究所 | 2018-04-27 | — | — | CN | claimed |
| CN-107827844-A | A kind of method for synthesizing butyrolactone derivative | 安徽华胜医药科技有限公司 | 2018-03-23 | — | — | CN | claimed |
| CN-107663185-A | Synthesis method of butyrolactone derivative | 安徽华胜医药科技有限公司 | 2018-02-06 | — | — | CN | claimed |
| CN-107129440-A | A kind of total synthesis method of natural products (+) negamycin | 上海应用技术大学 | 2017-09-05 | — | — | CN | claimed |
| CN-106832069-A | A kind of catalyst for olefinic polymerization and preparation method thereof | 营口市风光化工有限公司 | 2017-06-13 | — | — | CN | claimed |
| CN-104447374-A | Preparation method of sitagliptin and intermediate thereof | SHENZHEN HYBIO PHARMACEUTICAL | 2015-03-25 | — | — | CN | claimed |
| CN-103351443-A | Supported olefin polymerization catalyst, preparation method and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2013-10-16 | — | — | CN | claimed |
| CN-102786426-A | Synthetic method of stable isotope labeling ractopamine | SHANGHAI RES INST CHEMICAL IND | 2012-11-21 | — | — | CN | claimed |
| CN-101381292-B | Continuous preparation method of 3-methyl-2-propylene aldehyde | ZHEJIANG NHU CO LTD | 2012-02-29 | — | — | CN | claimed |
| CN-101381292-A | Continuous preparation method of 3-methyl-2-propylene aldehyde | ZHEJIANG XINHECHENG CO LTD (CN) | 2009-03-11 | — | — | CN | claimed |
| CN-101172978-A | Six-member heterocyclic compounds, prepare method and medical uses of the same | POISON MED INST PLA MED ACAD (CN) | 2008-05-07 | — | — | CN | claimed |
| CN-1798759-A | Process for preparing cyclosporin A analogs having a dienyl group | ISOTECHNIKA INC (CA) | 2006-07-05 | — | — | CN | claimed |
| EP-0241235-B1 | PROCESS FOR THE PREPARATION OF HOMOALLYL ALCOHOLS | ICI AUSTRALIA LIMITED (AU) | 1991-02-27 | — | — | EP | claimed |
| US-4933505-A | Method of preparing stereospecific nitroaldols | NORTHWESTERN UNIVERSITY (US) | 1990-06-12 | — | — | US | claimed |
| EP-0241235-A2 | Process for the preparation of homoallyl alcohols | ICI AUSTRALIA LIMITED (AU) | 1987-10-14 | — | — | EP | claimed |