Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.43 |
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.52 |
| ▸ | KDM5C | P41229 | 4/20 | 0.52 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.52 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.52 |
| ▸ | KDM6B | O15054 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28270066 | 0.97 | TSHR (0.77) | TSHRLMNAKDM4EEGLN1KDM5C | |
| Succinic Acid SCHEMBL18063898 | 0.97 | TSHR (0.77) | TSHRLMNAKDM4EEGLN1KDM5C | |
| Dimethyl Succinate SCHEMBL28154694 | 0.97 | TSHR (0.77) | TSHRLMNAKDM4EEGLN1KDM5C | |
| Dimethyl Succinate SCHEMBL20335703 | 0.97 | TSHR (0.77) | TSHRLMNAKDM4EEGLN1KDM5C | |
| SCHEMBL164072 | 0.97 | — | — | |
| Dimethyl Succinate SCHEMBL28606769 | 0.97 | TSHR (0.77) | TSHRLMNAKDM4EEGLN1KDM5C | |
| Dimethyl Succinate SCHEMBL29626086 | 0.97 | TSHR (0.77) | TSHRLMNAKDM4EEGLN1KDM5C | |
| SCHEMBL11672392 | 0.94 | TSHR (0.72) | TSHRLMNAKDM4EEGLN1KDM5C | |
| SCHEMBL6396564 | 0.94 | TSHR (0.72) | TSHRLMNAKDM4EEGLN1KDM5C | |
| Ammonia Solution, Strong SCHEMBL17600636 | 0.94 | TSHR (0.72) | TSHRLMNAKDM4EEGLN1KDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024160593-A1 | PROCESS FOR PURIFYING 2-PHENYL-4-(3-CARBOALKOXYPROPIONYL)-1,3-OXAZOLIN-5-ONE AND NEW CRYSTALLINE FORM B OF 2-PHENYL-4-(3-CARBOMETHOXYPROPIONYL)-1,3-OXAZOLIN-5-ONE | HERAEUS PRECIOUS METALS GMBH & CO. KG (DE) | 2024-08-08 | — | — | WO | claimed |
| EP-4410778-A1 | PROCESS FOR THE PURIFICATION OF 2-PHENYL-4-(3-CARBOALKOXYPROPIONYL)-1,3-OXAZOLIN-5-ONE AND NEW CRYSTALLINE FORM B OF 2-PHENYL-4-(3-CARBOMETHOXYPROPIONYL)-1,3-OXAZOLIN-5-ONE | Heraeus Precious Metals GmbH & Co. KG (DE) | 2024-08-07 | — | — | EP | claimed |
| CN-110723910-B | Cell culture material for controlling cell adhesion and cell detachment and preparation method thereof | 东南大学 | 2021-12-07 | — | — | CN | claimed |
| CN-110723910-A | Cell culture material for controlling cell adhesion and cell detachment and preparation method thereof | 东南大学 | 2020-01-24 | — | — | CN | claimed |
| CN-122055150-A | Cyproheptadine derivatives | 思凯生科股份有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-115845152-B | Medical apparatus and instruments | 元心科技(深圳)有限公司 | 2024-12-13 | — | — | CN | disclosed |
| WO-2024160593-A1 | PROCESS FOR PURIFYING 2-PHENYL-4-(3-CARBOALKOXYPROPIONYL)-1,3-OXAZOLIN-5-ONE AND NEW CRYSTALLINE FORM B OF 2-PHENYL-4-(3-CARBOMETHOXYPROPIONYL)-1,3-OXAZOLIN-5-ONE | HERAEUS PRECIOUS METALS GMBH & CO. KG (DE) | 2024-08-08 | — | — | WO | disclosed |
| EP-4410778-A1 | PROCESS FOR THE PURIFICATION OF 2-PHENYL-4-(3-CARBOALKOXYPROPIONYL)-1,3-OXAZOLIN-5-ONE AND NEW CRYSTALLINE FORM B OF 2-PHENYL-4-(3-CARBOMETHOXYPROPIONYL)-1,3-OXAZOLIN-5-ONE | Heraeus Precious Metals GmbH & Co. KG (DE) | 2024-08-07 | — | — | EP | disclosed |
| CN-117863679-A | Manufacturing process of polyethylene non-woven fabric high-water-pressure-resistance fabric | 华懋（厦门）特种材料有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117720466-A | 2 '-acetyl-2', 3 '-dihydro-4'H-spiro [ cyclohexane-1, 1 '-isoquinoline ] -4' -ketone compound and preparation method and application thereof | 承德医学院 | 2024-03-19 | — | — | CN | disclosed |
| CN-117229215-A | Biaryl compound, pharmaceutical composition containing biaryl compound, preparation method and application of biaryl compound | 四川科伦博泰生物医药股份有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-114096525-B | Biaryl compound, pharmaceutical composition containing biaryl compound, preparation method and application of biaryl compound | 四川科伦博泰生物医药股份有限公司 | 2023-10-13 | — | — | CN | disclosed |
| US-4265892-A | Cephalosporins having an α-acylaminoacetic acid side chain | CIBA-GEIGY CORPORATION (US) | 1981-05-05 | — | — | US | disclosed |
| US-4162314-A | ANTIBIOTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-07-24 | — | — | US | disclosed |
| US-4154831-A | Cephalosporins having an α-acylaminoacetic acid side chain | CIBA-GEIGY CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |
| US-4137323-A | 4-OXO-4H-BENZO(4,5)CYCLOHEPTA(1,2-B)THIOPHEN-2-YL-OXOALKANOIC ACIDS AND ESTERS, ANTIARTHRITICS, ANTIEDEMICS AND ANTIPHLOGISTICS | SANDOZ LTD. (CH) | 1979-01-30 | — | — | US | disclosed |
| US-4052412-A | ANTIPHLOGISTIC, ANTIARTHRITIC | SANDOZ LTD. (CH) | 1977-10-04 | — | — | US | disclosed |
| US-4041161-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |
| US-4036877-A | Process for the production of aldehydes | BUDAPESTI MUSZAKI EGYETEM (HU) | 1977-07-19 | — | — | US | disclosed |
| US-4025501-A | Polypeptide propoxyphene derivatives for immunoassay reagents | SYVA COMPANY (US) | 1977-05-24 | — | — | US | disclosed |