Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1834785 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL9315667 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL7378891 | 0.77 | — | — | |
| SCHEMBL6951714 | 0.77 | GRM4 (0.32) | — | |
| SCHEMBL1741062 | 0.77 | — | — | |
| SCHEMBL723881 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL2877397 | 0.76 | — | — | |
| SCHEMBL28003206 | 0.74 | — | — | |
| Carbimide SCHEMBL27821215 | 0.74 | CYP1A2 (0.38) | — | |
| SCHEMBL6946251 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108926743-A | A kind of three-dimensional mineralized collagen timbering material and its osteanagenesis application | 杭州恒睿生物科技有限公司 | 2018-12-04 | — | — | CN | claimed |
| CN-105758918-B | A kind of preparation of the DNA sensor based on electroreduction graphene oxide and decorated by nano-gold electrode and application process | 青岛科技大学 | 2018-10-12 | — | — | CN | claimed |
| CN-106496585-A | Sensitive graphene oxide based nano-materials of a kind of ROS and its preparation method and application | 浙江大学 | 2017-03-15 | — | — | CN | claimed |
| CN-105758918-A | Preparation and application method of electrochemical reduction graphene oxide and nanogold modified electrode based DNA sensor | 青岛科技大学 | 2016-07-13 | — | — | CN | claimed |
| CN-100519759-C | Method for preparing agglutination reagent for rapidly detecting typhoid fever | DEFENSE RES & DEV ORGANISATION (IN) | 2009-07-29 | — | — | CN | claimed |
| CN-1742096-A | A process for preparation of an agglutination reagent for rapid detection of typhoid | DEFENSE RES & DEV ORGANISATION (IN) | 2006-03-01 | — | — | CN | claimed |
| CN-86101066-A | Process for producing novel trifluoromethyl ketone substituted peptide derivatives | — | 1986-11-05 | — | — | CN | claimed |
| US-12037321-B2 | 1,2,4-oxadiazole derivatives as immunomodulators | AURIGENE ONCOLOGY LIMITED (IN) | 2024-07-16 | — | — | US | disclosed |
| US-11981685-B2 | Bicyclic heterocyclyl derivatives as IRAK4 inhibitors | AURIGENE ONCOLOGY LIMITED (IN) | 2024-05-14 | — | — | US | disclosed |
| EP-4353324-A2 | BICYCLIC HETEROCYCLYL DERIVATIVES AS IRAK4 INHIBITORS | Aurigene Oncology Limited (IN) | 2024-04-17 | — | — | EP | disclosed |
| EP-3805233-B1 | (R) AND (S) ENANTIOMERS OF N-(5-(3-HYDROXYPYRROLIDIN-1-YL)-2-MORPHOLINOOXAZOLO[4,5-B]PYRIDIN-6-YL)-2-(2-METHYLPYRIDIN-4-YL)OXAZOLE-CARBOXAMIDE AS IRAK4 INHIBITORS FOR THE TREATMENT OF CANCER | AURIGENE ONCOLOGY LTD (IN) | 2024-03-06 | — | — | EP | disclosed |
| US-20230331740-A1 | BICYCLIC HETEROCYCLYL DERIVATIVES AS IRAK4 INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2023-10-19 | — | — | US | disclosed |
| US-11691987-B2 | Bicyclic heterocyclyl derivatives as IRAK4 inhibitors | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2023-07-04 | — | — | US | disclosed |
| US-5004697-A | Cationized antibodies for delivery through the blood-brain barrier | UNIV. OF CA (US) | 1991-04-02 | — | — | US | disclosed |
| EP-0274496-A4 | COMPOSITION AND METHOD FOR IMMUNOLOGICAL CASTRATION AND SPAYING. | VICTORIA STATE (AU) | 1989-12-19 | — | — | EP | disclosed |
| WO-1989001343-A1 | CATIONIZED ANTIBODIES FOR DELIVERY THROUGH THE BLOOD-BRAIN BARRIER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1989-02-23 | — | — | WO | disclosed |
| EP-0274496-A1 | COMPOSITION AND METHOD FOR IMMUNOLOGICAL CASTRATION AND SPAYING | THE STATE OF VICTORIA (AU) | 1988-07-20 | — | — | EP | disclosed |
| WO-1988000056-A1 | COMPOSITION AND METHOD FOR IMMUNOLOGICAL CASTRATION AND SPAYING | THE STATE OF VICTORIA (AU) | 1988-01-14 | — | — | WO | disclosed |
| WO-1987005941-A1 | MICROCHEMILUMINESCENT ASSAY FOR DETECTION AND QUANTIFICATION OF OXIDATIVE INJURY TO CELLS | MCLAS TECHNOLOGIES, INC. (US) | 1987-10-08 | — | — | WO | disclosed |
| EP-0175577-A2 | Microchemiluminescent assay system | Kiel, Jonathan L (US) | 1986-03-26 | — | — | EP | disclosed |