Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | SELP | P16109 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29528833 | 1.00 | FAAH (0.49) | FAAHNAAADNM1PSMD14PLA2G1B | |
| Hydrochloric Acid SCHEMBL15534461 | 1.00 | FAAH (0.49) | FAAHNAAADNM1PSMD14PLA2G1B | |
| Hydrochloric Acid SCHEMBL15534882 | 1.00 | FAAH (0.49) | FAAHNAAADNM1PSMD14PLA2G1B | |
| SCHEMBL29817227 | 0.99 | FAAH (0.50) | FAAHNAAADNM1PSMD14PLA2G1B | |
| SCHEMBL20959426 | 0.99 | FAAH (0.50) | FAAHNAAADNM1PSMD14PLA2G1B | |
| Hydrochloric Acid SCHEMBL25218420 | 0.93 | EPHX2 (0.55) | EPHX2CNR1ALDH1A1HPGDTRPV1 | |
| Hydrochloric Acid SCHEMBL9179808 | 0.93 | EPHX2 (0.55) | EPHX2CNR1ALDH1A1HPGDTRPV1 | |
| SCHEMBL10329406 | 0.92 | FAAH (0.54) | FAAHNAAADNM1PSMD14PLA2G1B | |
| Hydrochloric Acid SCHEMBL30274291 | 0.91 | FAAH (0.50) | FAAHNAAADNM1PSMD14PLA2G1B | |
| SCHEMBL17707881 | 0.89 | FAAH (0.51) | FAAHNAAADNM1PSMD14PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260055056-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | WILLIAM M YARBROUGH FOUND (US) | 2026-02-26 | — | — | US | claimed |
| US-12310939-B2 | Method for treating rheumatoid arthritis | THE WILLIAM YARBROUGH FOUNDATION (US) | 2025-05-27 | — | — | US | claimed |
| US-20250161258-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | THE WILLIAM M YARBROUGH FOUND (US) | 2025-05-22 | — | — | US | claimed |
| US-12239626-B2 | Method for treating infectious diseases with isothiocyanate functional compounds | THE WILLIAM YARBROUGH FOUNDATION (US) | 2025-03-04 | — | — | US | claimed |
| US-12178795-B2 | Method for treating metastatic prostate cancer | THE WILLIAM YARBROUGH FOUNDATION (US) | 2024-12-31 | — | — | US | claimed |
| US-20230338324-A1 | METHOD FOR TREATING RHEUMATOID ARTHRITIS | THE WILLIAM M YARBROUGH FOUNDATION | 2023-10-26 | — | — | US | claimed |
| US-20230263763-A1 | METHOD FOR TREATING INFECTIOUS DISEASES WITH ISOTHIOCYANATE FUNCTIONAL COMPOUNDS | THE WILLIAM M YARBROUGH FOUNDATION | 2023-08-24 | — | — | US | claimed |
| US-20230255920-A1 | METHOD FOR TREATING METASTATIC PROSTATE CANCER | THE WILLIAM M YARBROUGH FOUNDATION | 2023-08-17 | — | — | US | claimed |
| CN-115605037-A | Film forming method, light emitting device and preparation method thereof | TCL科技集团股份有限公司（CN） | 2023-01-13 | — | — | CN | claimed |
| US-20260096558-A1 | THE USE OF PHYTIC ACID CHELATOR FOR MICROBIAL RAPID KILL | HENKEL AG & CO KGAA (DE) | 2026-04-09 | — | — | US | disclosed |
| US-12534691-B2 | Potential of hydrogen (pH) stabilized cleaning formulations | ENVIROX, L.L.C. (US) | 2026-01-27 | — | — | US | disclosed |
| US-20260015558-A1 | STABILIZATION OF HYDROGEN PEROXIDE CONTAINING FORMULATIONS WITH TWO-COMPONENT SYNERGISTIC STABILIZERS | DAVIS JOHN P (US) | 2026-01-15 | — | — | US | disclosed |
| US-20260015559-A1 | POTENTIAL OF HYDROGEN (pH) STABILIZED CLEANING FORMULATIONS | DAVIS JOHN P (US) | 2026-01-15 | — | — | US | disclosed |
| US-12522746-B2 | Cationic-stabilized dispersions, hybridized cationic-stabilized dispersions, in-mold coated articles prepared utilizing such stabilized dispersions, and methods for manufacturing same | RED SPOT PAINT & VARNISH CO., INC. (US) | 2026-01-13 | — | — | US | disclosed |
| WO-2009045456-A1 | COMPOSITIONS AND METHODS FOR TREATING MASTITIS | BYOCOAT ENTERPRISES, INC. (PR) | 2009-04-09 | — | — | WO | disclosed |
| EP-1813254-A2 | Hair bleach composition and hair dye composition | Kao Corporation (JP) | 2007-08-01 | — | — | EP | disclosed |
| EP-1219285-B1 | Hair bleach composition and hair dye composition | KAO CORP (JP) | 2007-03-28 | — | — | EP | disclosed |
| US-6916432-B2 | Hair bleach composition and hair dye composition | KAO CORPORATION (JP) | 2005-07-12 | — | — | US | disclosed |
| US-20020139957-A1 | Hair bleach composition and hair dye composition | KAO CORPORATION (JP) | 2002-10-03 | — | — | US | disclosed |
| EP-1219285-A2 | Hair bleach composition and hair dye composition | Kao Corporation (JP) | 2002-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260055056-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | ALK, C9, MSR1 | FAAH 1590/4885NAAA 1522/4885DNM1 4860/4885 |
| US-12178795-B2 | Method for treating metastatic prostate cancer | BPHL, KLK3, ACP3 | FAAH 1303/4885NAAA 532/4885DNM1 3577/4885 |
| US-12239626-B2 | Method for treating infectious diseases with isothiocyanate functional compounds | CFTR, TST, ICMT | FAAH 2592/4885NAAA 394/4885DNM1 3945/4885 |
| US-12310939-B2 | Method for treating rheumatoid arthritis | MIF, TNF, MMP12 | FAAH 1121/4885NAAA 1566/4885DNM1 3267/4885 |
| US-12534691-B2 | Potential of hydrogen (pH) stabilized cleaning formulations | PLD1, PLD2, GPX4 | FAAH 144/4885NAAA 462/4885DNM1 798/4885 |
| US-20250161258-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | TST, TMSB10, NHERF1 | FAAH 3558/4885NAAA 1765/4885DNM1 3740/4885 |
| US-20020139957-A1 | Hair bleach composition and hair dye composition | OR10J3, LBR, POLL | FAAH 1185/4885NAAA 3847/4885DNM1 2524/4885 |
| US-20260096558-A1 | THE USE OF PHYTIC ACID CHELATOR FOR MICROBIAL RAPID KILL | CUTA, TRAFD1, POLR1C | FAAH 1378/4885NAAA 149/4885DNM1 511/4885 |
| US-20260015559-A1 | POTENTIAL OF HYDROGEN (pH) STABILIZED CLEANING FORMULATIONS | PLD1, DAGLB, PLD2 | FAAH 90/4885NAAA 1002/4885DNM1 1122/4885 |
| US-20260015558-A1 | STABILIZATION OF HYDROGEN PEROXIDE CONTAINING FORMULATIONS WITH TWO-COMPONENT SYNERGISTIC STABILIZERS | GPX4, HAO2, LPO | FAAH 663/4885NAAA 2794/4885DNM1 2056/4885 |
| US-20230338324-A1 | METHOD FOR TREATING RHEUMATOID ARTHRITIS | MIF, TNF, MMP12 | FAAH 1272/4885NAAA 1666/4885DNM1 3487/4885 |
| US-20230263763-A1 | METHOD FOR TREATING INFECTIOUS DISEASES WITH ISOTHIOCYANATE FUNCTIONAL COMPOUNDS | CFTR, TST, ICMT | FAAH 2592/4885NAAA 394/4885DNM1 3945/4885 |
| US-20230255920-A1 | METHOD FOR TREATING METASTATIC PROSTATE CANCER | BPHL, KLK3, ACP3 | FAAH 1303/4885NAAA 532/4885DNM1 3577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.