SCHEMBL1448847

SCHEMBL1448847

CC1(C)OB(c2ccc(-c3nc4ccccc4s3)cc2)OC1(C)C

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.66
LPL P06858 2/20 0.54
LIPG Q9Y5X9 2/20 0.54
APP P05067 6/20 0.54
RAB9A P51151 5/20 0.54
NPC1 O15118 4/20 0.54
KDM4E B2RXH2 3/20 0.54
GLA P06280 2/20 0.54
GAA P10253 2/20 0.54
MAPT P10636 2/20 0.54
MMP9 P14780 2/20 0.54
MMP8 P22894 2/20 0.54
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.54
PKM P14618 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
PAX8 Q06710 1/20 0.54
NOD2 Q9HC29 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21313409 0.88 SNCA (0.55) SNCAAPPRAB9ANPC1KDM4E
SCHEMBL2496185 0.85 RAB9A (0.53) SNCAAPPRAB9ANPC1KDM4E
SCHEMBL732658 0.85 SNCA (0.58) SNCALPLLIPGAPPRAB9A
SCHEMBL16445941 0.84 SNCA (0.67) SNCALPLLIPGAPPRAB9A
SCHEMBL593486 0.84 SNCA (0.57) SNCALPLLIPGAPPRAB9A
SCHEMBL30837503 0.83 RAB9A (0.51) SNCAAPPRAB9ANPC1KDM4E
SCHEMBL19106702 0.83 RAB9A (0.51) SNCAAPPRAB9ANPC1KDM4E
SCHEMBL805840 0.83 RAB9A (0.48) SNCALPLLIPGAPPRAB9A
SCHEMBL12944754 0.82 SNCA (0.47) SNCAAPPRAB9ANPC1KDM4E
SCHEMBL30476999 0.81 SNCA (0.49) SNCALPLLIPGAPPRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129059-A1 PYRIMIDINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO., LTD. (JP) 2025-04-24 US disclosed
WO-2025053219-A1 BENZOAZOLE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAID COMPOUND 保土谷化学工業株式会社 2025-03-13 WO disclosed
EP-4464702-A1 PYRIMIDINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2024-11-20 EP disclosed
US-20240049595-A1 HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS HODOGAYA CHEMICAL CO., LTD. (JP) 2024-02-08 US disclosed
EP-4257585-A1 HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE Hodogaya Chemical Co., Ltd. (JP) 2023-10-11 EP disclosed
WO-2023136295-A1 PYRIMIDINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2023-07-20 WO disclosed
WO-2023136295-A1 PYRIMIDINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2023-07-20 WO disclosed
CN-109791984-B Material for photoelectric conversion element for imaging element and photoelectric conversion element containing same 日本化药株式会社 2023-02-07 CN disclosed
US-11374044-B2 Material for photoelectric conversion element for use in imaging element, and photoelectric conversion element including same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2022-06-28 US disclosed
US-11362283-B2 Organic electroluminescent element LG CHEM, LTD. 2022-06-14 US disclosed
WO-2011034967-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS NITTO DENKO CORPORATION (JP) 2011-03-24 WO disclosed
US-20110062386-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS NITTO DENKO CORPORATION (JP) 2011-03-17 US disclosed
US-20110062386-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS NITTO DENKO CORPORATION (JP) 2011-03-17 US disclosed
US-20110062386-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS NITTO DENKO CORPORATION (JP) 2011-03-17 US disclosed
US-20110049495-A1 QUINOXALINE DERIVATIVES AND ORGANIC LIGHT-EMITTING DIODES COMPRISING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2011-03-03 US disclosed
US-20110049495-A1 QUINOXALINE DERIVATIVES AND ORGANIC LIGHT-EMITTING DIODES COMPRISING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2011-03-03 US disclosed
US-20100326526-A1 EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2010-12-30 US disclosed
US-20100326526-A1 EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2010-12-30 US disclosed
US-20100230660-A1 COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT HODOGAYA CHEMICAL CO., LTD. (JP) 2010-09-16 US disclosed
EP-2053051-A1 COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2009-04-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11362283-B2 Organic electroluminescent element NCS1, POU5F1, POU2F1 SNCA 4086/4885LPL 1156/4885LIPG 477/4885
US-20110049495-A1 QUINOXALINE DERIVATIVES AND ORGANIC LIGHT-EMITTING DIODES COMPRISING THE SAME PDXK, PPOX, QDPR SNCA 1219/4885LPL 2821/4885LIPG 3841/4885
US-20100230660-A1 COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT SCO2, PNPO, WEE1 SNCA 2516/4885LPL 3623/4885LIPG 4091/4885
US-11374044-B2 Material for photoelectric conversion element for use in imaging element, and photoelectric conversion element including same SLC19A1, SLC46A1, SLC19A2 SNCA 2841/4885LPL 2997/4885LIPG 1535/4885
US-20110062386-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS ALOX12, ALOX15B, ALOX15 SNCA 1833/4885LPL 475/4885LIPG 1471/4885
US-20250129059-A1 PYRIMIDINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, YBX1, YBX3 SNCA 3961/4885LPL 3808/4885LIPG 4285/4885
US-20100326526-A1 EMISSIVE ARYL-HETEROARYL COMPOUNDS AHR, AR, ARNT SNCA 382/4885LPL 731/4885LIPG 2115/4885
US-20240049595-A1 HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS LAGE3, EED, EZH1 SNCA 2740/4885LPL 1785/4885LIPG 735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.