SCHEMBL14935818

SCHEMBL14935818

O=C(O)C(CCS)NCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.46
GGT1 P19440 3/20 0.46
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
POLB P06746 1/20 0.44
TLR2 O60603 1/20 0.44
MME P08473 2/20 0.44
CPA3 P15088 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7270248 1.00 FOLH1 (0.46) FOLH1GGT1GAAMAPTPOLB
SCHEMBL341584 1.00 FOLH1 (0.46) FOLH1GGT1GAAMAPTPOLB
Benzenemethanethiol SCHEMBL11583112 0.95 POLB (0.44) FOLH1GGT1GAAMAPTPOLB
SCHEMBL1109641 0.86 CPA3 (0.50) FOLH1GAAMAPTPOLBMME
SCHEMBL515921 0.86 CPA3 (0.50) FOLH1GAAMAPTPOLBMME
SCHEMBL1031027 0.86 CPA3 (0.50) FOLH1GAAMAPTPOLBMME
SCHEMBL31425145 0.85 ALDH1A1 (0.48) FOLH1POLB
SCHEMBL6051729 0.85 SMN1; SMN2 (0.45)
SCHEMBL10482542 0.84 MME (0.56) GGT1GAAMAPTPOLBMME
SCHEMBL21274596 0.84 GGT1 (0.47) GGT1GAAMAPTPOLBTLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250367300-A1 Nanomaterial and Methods of Use Thereof UNIVERSITY OF CONNECTICUT (US) 2025-12-04 US disclosed
US-20250302762-A1 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF UNIVERSITY OF CONNECTICUT (US) 2025-10-02 US disclosed
US-20250302971-A1 Therapeutic Nanomaterials UNIV CONNECTICUT (US) 2025-10-02 US disclosed
US-20250229081-A1 NANOMATERIAL COATED ELECTRODE AND METHODS OF USE THEREOF UNIVERSITY OF CONNECTICUT 2025-07-17 US disclosed
CN-120202010-A Ligand-oligonucleotide conjugates and linkers for use therewith 上海京新生物医药有限公司 2025-06-24 CN disclosed
US-20250084410-A1 INCORPORATION OF UNNATURAL NUCLEOTIDES AND METHODS THEREOF Synthorx, Inc. (US) 2025-03-13 US disclosed
US-20250066799-A1 UNNATURAL BASE PAIR COMPOSITIONS AND METHODS OF USE THE SCRIPPS RESEARCH INSTITUTE 2025-02-27 US disclosed
US-12214043-B2 Therapeutic nanomaterials UNIVERSITY OF CONNECTICUT 2025-02-04 US disclosed
US-12173291-B2 Unnatural base pair compositions and methods of use THE SCRIPPS RESEARCH INSTITUTE (US) 2024-12-24 US disclosed
CN-118879592-A Unnatural base pair compositions and methods of use 斯克利普斯研究所 2024-11-01 CN disclosed
US-20150183825-A1 TRIAZOLE-CROSSLINKED AND THIOETHER-CROSSLINKED PEPTIDOMIMETIC MACROCYCLES AILERON THERAPEUTICS, INC. 2015-07-02 US disclosed
US-8987414-B2 Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles AILERON THERAPEUTICS, INC. (US) 2015-03-24 US disclosed
US-20150051155-A1 PEPTIDOMIMETIC MACROCYCLES HOFFMANN-LA ROCHE, INC. 2015-02-19 US disclosed
US-8927500-B2 Peptidomimetic macrocycles AILERON THERAPEUTICS, INC. (US) 2015-01-06 US disclosed
CN-104159595-A Peptidomimetic macrocycles AILERON THERAPEUTICS INC 2014-11-19 CN disclosed
CN-104144695-A Triazole-and thioether-crosslinked peptidomimetic macrocycles AILERON THERAPEUTICS INC 2014-11-12 CN disclosed
CN-104039342-A Peptidomimetic macrocycles AILERON THERAPEUTICS INC 2014-09-10 CN disclosed
US-20130274205-A1 PEPTIDOMIMETIC MACROCYCLES AILERON THERAPEUTICS, INC. 2013-10-17 US disclosed
US-20130210745-A1 TRIAZOLE-CROSSLINKED AND THIOETHER-CROSSLINKED PEPTIDOMIMETIC MACROCYCLES AILERON THERAPEUTICS, INC. (US) 2013-08-15 US disclosed
US-20130123169-A1 PEPTIDOMIMETIC MACROCYCLES AILERON THERAPEUTICS, INC. (US) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250302971-A1 Therapeutic Nanomaterials TIE1, TEKT1, POLRMT FOLH1 1650/4885GGT1 2996/4885GAA 3358/4885
US-20250367300-A1 Nanomaterial and Methods of Use Thereof EPCAM, CD47, JAK2 FOLH1 2480/4885GGT1 2054/4885GAA 2661/4885
US-20250302762-A1 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF JAK2, JAK1, CHMP4B FOLH1 1458/4885GGT1 4387/4885GAA 3593/4885
US-12173291-B2 Unnatural base pair compositions and methods of use RNGTT, SPOUT1, NPEPPS FOLH1 230/4885GGT1 1459/4885GAA 1504/4885
US-20250066799-A1 UNNATURAL BASE PAIR COMPOSITIONS AND METHODS OF USE RNGTT, SPOUT1, NPEPPS FOLH1 230/4885GGT1 1459/4885GAA 1504/4885
US-20150051155-A1 PEPTIDOMIMETIC MACROCYCLES TP53, MDM2, MDM4 FOLH1 1179/4885GGT1 2584/4885GAA 3916/4885
US-20250084410-A1 INCORPORATION OF UNNATURAL NUCLEOTIDES AND METHODS THEREOF RNGTT, TRMT1, OSGEP FOLH1 662/4885GGT1 713/4885GAA 850/4885
US-20130123169-A1 PEPTIDOMIMETIC MACROCYCLES GHRHR, GHSR, GHITM FOLH1 336/4885GGT1 1662/4885GAA 2039/4885
US-12214043-B2 Therapeutic nanomaterials TIE1, TEKT1, POLRMT FOLH1 1650/4885GGT1 2996/4885GAA 3358/4885
US-20130210745-A1 TRIAZOLE-CROSSLINKED AND THIOETHER-CROSSLINKED PEPTIDOMIMETIC MACROCYCLES IL33, TPR, CDC37 FOLH1 1229/4885GGT1 2457/4885GAA 4180/4885
US-20130274205-A1 PEPTIDOMIMETIC MACROCYCLES PROKR1, GLP1R, PROKR2 FOLH1 74/4885GGT1 2719/4885GAA 1940/4885
US-20150183825-A1 TRIAZOLE-CROSSLINKED AND THIOETHER-CROSSLINKED PEPTIDOMIMETIC MACROCYCLES IL33, TPR, CDC37 FOLH1 1229/4885GGT1 2457/4885GAA 4180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.