Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27987326 | 1.00 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL28190850 | 1.00 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL30037654 | 1.00 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL16830204 | 1.00 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL19411863 | 1.00 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL23499239 | 0.97 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL3036597 | 0.97 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL28041925 | 0.97 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL19411922 | 0.97 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL5380488 | 0.97 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110526906-A | A kind of preparation method of epoxiconazole | JIANGSU SEVENCONTINENT GREEN CHEMICAL CO LTD | 2019-12-03 | — | — | CN | claimed |
| CN-109694957-A | A method of utilizing ion liquid abstraction lithium ion battery leachate metal ion | 中国科学院城市环境研究所 | 2019-04-30 | — | — | CN | claimed |
| CN-109504015-A | Electrochromic polymeric compounds material based on combined strategy and prepare electrochromic device | 常州铱视光电科技有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-109331866-A | A kind of dehydrochlorination catalyst and its preparation method and application | 浙江工业大学 | 2019-02-15 | — | — | CN | claimed |
| CN-108949141-A | The preparation method of bistable state electrochromic material and it is used to prepare electrochromic device | 常州铱视光电科技有限公司 | 2018-12-07 | — | — | CN | claimed |
| CN-108795407-A | Based on the electroluminescent sour electrochromic material acted on and prepare electrochromic device | 常州铱视光电科技有限公司 | 2018-11-13 | — | — | CN | claimed |
| CN-108393068-A | Chitosan soft capsule, preparation method and its application | 中南民族大学 | 2018-08-14 | — | — | CN | claimed |
| CN-105655602-B | A kind of magnesium air cell Mn2O3And Mn3O4The nanocube elctro-catalyst design synthesis of mixture phase | 华北理工大学 | 2018-01-26 | — | — | CN | claimed |
| CN-105861827-B | A kind of soda acid coupling extraction system separated for many metal solution extractions and its application | 中南大学 | 2017-09-12 | — | — | CN | claimed |
| CN-106029626-A | A catalyst recovery and recycling process during aromatic carboxylic acid production | 瑞来斯实业公司 | 2016-10-12 | — | — | CN | claimed |
| CN-105925246-A | Electricity generated acid produced by blending substances with changeable oxidation state and electrolyte and applications thereof | 吉林大学 | 2016-09-07 | — | — | CN | claimed |
| CN-105861827-A | Acid-alkaline coupling extraction system used for extraction and separation of multi-metal solutions and application thereof | 中南大学 | 2016-08-17 | — | — | CN | claimed |
| CN-105838350-A | Electrochromic composite material and prepared electrochromic device | 吉林大学 | 2016-08-10 | — | — | CN | claimed |
| CN-105655602-A | Design synthesis method of nanocubic electrocatalyst with Mn2O3 and Mn3O4 mixture phase and for magnesium air battery | 华北理工大学 | 2016-06-08 | — | — | CN | claimed |
| CN-105655670-A | Controllable preparation method of manganese oxide super long nanowire/graphene electrocatalyst for magnesium air battery | 华北理工大学 | 2016-06-08 | — | — | CN | claimed |
| CN-103553141-B | Method for synthesizing ferrous acid manganese nanowire material through ionic liquid assisted microwave radiation method | UNIV TAIYUAN TECHNOLOGY | 2014-12-10 | — | — | CN | claimed |
| CN-104143494-A | Component of a plasma processing apparatus having a protective in situ formed layer on a plasma exposed surface | LAM RES CORP | 2014-11-12 | — | — | CN | claimed |
| CN-101932526-B | Methods and compositions for the removal of impurities and water from the bayer process | CYTEC TECH CORP | 2014-05-28 | — | — | CN | claimed |
| CN-103553141-A | Method for synthesizing ferrous acid manganese nanowire material through ionic liquid assisted microwave radiation method | UNIV TAIYUAN TECHNOLOGY | 2014-02-05 | — | — | CN | claimed |
| CN-101932526-A | Methods and compositions for the removal of impurities and water from the bayer process | CYTEC TECH CORP | 2010-12-29 | — | — | CN | claimed |