Tromethamine

Tromethamine

SCHEMBL1509014

NC(CO)(CO)CO.O=P(O)(O)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

DHFRGARTPTGFRPTGIRPTGS1PTGS2TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8envmurAthyA

The experimentally established mechanism targets of Tromethamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.67
MEN1 O00255 1/20 0.67
KMT2A Q03164 1/20 0.67
FDPS P14324 6/20 0.38
GRM4 Q14833 1/20 0.36
S1PR1 P21453 6/20 0.33
S1PR3 Q99500 6/20 0.33
S1PR2 O95136 2/20 0.33
S1PR4 O95977 2/20 0.33
ADRB3 P13945 1/20 0.32
PDE4D Q08499 1/20 0.32
PDE3A Q14432 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ENPP2 Q13822 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MMP2 P08253 1/20 0.32
THRB P10828 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
SMPD1 P17405 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tromethamine SCHEMBL7899122 1.00 LMNA (0.67) LMNAMEN1KMT2AFDPSGRM4
Tromethamine SCHEMBL10930305 0.87 LMNA (0.50) LMNAMEN1KMT2AFDPSGRM4
Tromethamine SCHEMBL29366645 0.85 KMT2A (0.56) LMNAMEN1KMT2AFDPSGRM4
Tromethamine SCHEMBL7572662 0.85 LMNA (0.56) LMNAMEN1KMT2AFDPSGRM4
Tromethamine SCHEMBL29130482 0.83 KMT2A (0.53) LMNAMEN1KMT2AFDPSGRM4
Phosphoric Acid SCHEMBL11822162 0.83 LMNA (0.45) LMNAMEN1KMT2AFDPSGRM4
Tromethamine SCHEMBL975 0.82
Tromethamine SCHEMBL3696191 0.82
Tromethamine SCHEMBL17484 0.82 MEN1 (1.00) LMNAMEN1KMT2AS1PR1S1PR3
Tromethamine SCHEMBL2202687 0.81 KMT2A (0.59) LMNAMEN1KMT2AFDPSS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119925276-A CRAC inhibitor freeze-dried powder preparation based on tromethamine phosphate salt prodrug and preparation method thereof 天津辰欣药物研究有限公司 2025-05-06 CN claimed
CN-117343966-A Method for producing hydroxyl free radical by oxidase-phthalocyanine supermolecule near infrared enzyme cascade catalysis 吉林大学 2024-01-05 CN claimed
CN-115677821-A Antibacterial peptide and preparation method thereof 韩玉玲 2023-02-03 CN claimed
CN-112457372-B Synthesis method and application of polypeptide hydrazide containing cysteine residues 华南理工大学 2021-09-21 CN claimed
CN-110218778-B PCR reaction system, reagent, kit and PCR method 珠海宝锐生物科技有限公司 2021-05-28 CN claimed
CN-112457372-A Synthesis method and application of polypeptide hydrazide containing cysteine residues 华南理工大学 2021-03-09 CN claimed
EP-3684835-A1 COLOUR-STABLE CURING COMPOSITIONS CONTAINING POLYISOCYANATE (CYCLO)ALIPHATIC DIISOCYANATES BASF SE (DE) 2020-07-29 EP claimed
EP-3684833-A1 METHOD FOR PRODUCING POLYISOCYANATES OF (CYCLO)ALIPHATIC DIISOCYANATES WHICH ARE FLOCCULATION-STABLE IN SOLVENTS BASF SE (DE) 2020-07-29 EP claimed
CN-106574089-B Polymer composition with low olfactory sensory impression SABIC环球技术有限责任公司 2020-03-03 CN claimed
US-20130098775-A1 Glucose biosensor with improved shelf life NOVA BIOMEDICAL CORPORATION (US) 2013-04-25 US claimed
WO-2013059534-A1 GLUCOSE BIOSENSOR WITH IMPROVED SHELF LIFE NOVA BIOMEDICAL CORPORATION (US) 2013-04-25 WO claimed
EP-0506922-B1 INDIRECT POTENTIOMETRIC METHOD AND DILUENT FOR ANALYSIS OF LITHIUM BECKMAN INSTRUMENTS INC (US) 1996-01-31 EP claimed
US-5288678-A A mixtures of PH buffer and a non-cationic surfactant; medical diagnosis BECKMAN INSTRUMENTS, INC. (US) 1994-02-22 US claimed
EP-0304151-B1 Measurement of calcium ions INSTRUMENTATION LAB SPA (IT) 1993-12-15 EP claimed
EP-0506922-A1 INDIRECT POTENTIOMETRIC METHOD AND DILUENT FOR ANALYSIS OF LITHIUM. BECKMAN INSTRUMENTS INC (US) 1992-10-07 EP claimed
US-5110742-A Quantitative analysis of clinical sample; electrodes selective for lithium and for interfering ion BECKMAN INSTRUMENTS, INC. (US) 1992-05-05 US claimed
WO-1992007274-A1 INDIRECT POTENTIOMETRIC METHOD AND DILUENT FOR ANALYSIS OF LITHIUM BECKMAN INSTRUMENTS, INC. (US) 1992-04-30 WO claimed
US-4870024-A DILUTION WITH TRIS PHOSPHATE FISHER SCIENTIFIC COMPANY (US) 1989-09-26 US claimed
EP-0304151-A2 Measurement of calcium ions INSTRUMENTATION LABORATORY S.p.A. (IT) 1989-02-22 EP claimed
JP-9154571-A None JP disclosed
US-20260115287-A1 T CELL THERAPY IN PATIENTS WHO HAVE HAD PRIOR STEM CELL TRANSPLANT CELGENE CORPORATION (US) 2026-04-30 US disclosed
EP-4687843-A1 FORMULATIONS AND USES THEREOF Sartorius Albumedix Limited (GB) 2026-02-11 EP disclosed
EP-4676233-A1 ENRICHMENT OF A CASEIN IN A COMPOSITION NewMilkBuzz B.V (NL) 2026-01-14 EP disclosed
EP-4659809-A2 STEROIDS AND PROTEIN-CONJUGATES THEREOF Regeneron Pharmaceuticals, Inc. (US) 2025-12-10 EP disclosed
US-20250345432-A1 METHOD FOR PREDICTING RESPONSE TO A T CELL THERAPY CELGENE CORPORATION (US) 2025-11-13 US disclosed
US-20250295771-A1 METHODS AND USES RELATED TO T CELL THERAPY AND PRODUCTION OF SAME CELGENE CORPORATION (US) 2025-09-25 US disclosed
EP-3538539-B1 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMA (US) 2025-08-27 EP disclosed
US-20250207119-A1 METHODS AND COMPOSITIONS FOR INHIBITING ADAM10 BIOLOGICAL ACTIVITIES Verra Therapeutics, Inc. 2025-06-26 US disclosed
US-12297469-B2 Methods and compositions for inhibiting ADAM10 biological activities Verra Therapeutics, Inc. (US) 2025-05-13 US disclosed
EP-3828265-B1 IMPROVED T CELL COMPOSITIONS 2SEVENTY BIO INC (US) 2025-05-07 EP disclosed
CN-119925276-A CRAC inhibitor freeze-dried powder preparation based on tromethamine phosphate salt prodrug and preparation method thereof 天津辰欣药物研究有限公司 2025-05-06 CN disclosed
CN-119925276-A CRAC inhibitor freeze-dried powder preparation based on tromethamine phosphate salt prodrug and preparation method thereof 天津辰欣药物研究有限公司 2025-05-06 CN disclosed
CN-119925276-A CRAC inhibitor freeze-dried powder preparation based on tromethamine phosphate salt prodrug and preparation method thereof 天津辰欣药物研究有限公司 2025-05-06 CN disclosed
US-20250123281-A1 USES OF ANTI-BCMA CHIMERIC ANTIGEN RECEPTORS CELGENE CORPORATION (US) 2025-04-17 US disclosed
US-20250122276-A1 ANTIBODIES TO FELINE MCDONOUGH SARCOMA (FMS)-LIKE TYROSINE KINASE 3 RECEPTOR LIGAND (FLT3L) AND USES THEREOF FOR TREATING AUTOIMMUNE AND INFLAMMATORY DISEASES HORIZON THERAPEUTICS IRELAND DAC (IE) 2025-04-17 US disclosed
CN-119643849-A Pre-dyeing protein Marker and preparation method and application thereof 湖北擎科生物科技有限公司 2025-03-18 CN disclosed
US-20250064954-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2025-02-27 US disclosed
US-12209123-B2 Antibodies to Feline McDonough Sarcoma (FMS)-like tyrosine kinase 3 receptor ligand (FLT3L) and uses thereof for treating autoimmune and inflammatory diseases HORIZON THERAPEUTICS IRELAND DAC (IE) 2025-01-28 US disclosed
US-20250026845-A1 BCMA CHIMERIC ANTIGEN RECEPTORS 2SEVENTY BIO, INC. 2025-01-23 US disclosed
US-20250009710-A1 COMPOSITION CONTAINING ARTESUNATE ZHAO MING (US) 2025-01-09 US disclosed
US-20240342299-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMA (US) 2024-10-17 US disclosed
WO-2024209085-A1 FORMULATIONS AND USES THEREOF ALBUMEDIX LTD (GB) 2024-10-10 WO disclosed
EP-4438734-A2 REPROGRAMMING OF CELLS TO A NEW FATE The Scripps Research Institute (US) 2024-10-02 EP disclosed
WO-2024188832-A1 ENRICHMENT OF A CASEIN IN A COMPOSITION NEWMILKBUZZ B.V (NL) 2024-09-19 WO disclosed
US-12083096-B2 Composition containing artesunate ZHAO MING (US) 2024-09-10 US disclosed
US-12060419-B2 CD79A chimeric antigen receptors REGENERON PHARMACEUTICALS, INC. (US) 2024-08-13 US disclosed
US-12029784-B2 BCMA chimeric antigen receptors 2SEVENTY BIO, INC. (US) 2024-07-09 US disclosed
EP-3399026-B1 REPROGRAMMING OF CELLS TO A NEW FATE SCRIPPS RESEARCH INST (US) 2024-06-26 EP disclosed
EP-4365194-A2 CD79A CHIMERIC ANTIGEN RECEPTORS 2seventy bio, Inc. (US) 2024-05-08 EP disclosed
CN-116751812-B Application of OsABI gene in enhancing nitrogen deficiency stress resistance of rice 浙江大学海南研究院 2024-05-03 CN disclosed
CN-117964742-A Artificial metalloenzyme based on myoglobin scaffold, and chemical synthesis method and application thereof 华南理工大学 2024-05-03 CN disclosed
EP-4322991-A1 T CELL THERAPY IN PATIENTS WHO HAVE HAD PRIOR STEM CELL TRANSPLANT CELGENE CORPORATION (US) 2024-02-21 EP disclosed
EP-3806903-B1 CD79A CHIMERIC ANTIGEN RECEPTORS 2SEVENTY BIO INC (US) 2024-02-14 EP disclosed
CN-117343966-A Method for producing hydroxyl free radical by oxidase-phthalocyanine supermolecule near infrared enzyme cascade catalysis 吉林大学 2024-01-05 CN disclosed
US-20230407401-A1 DNA DAMAGE DEPENDENT MICRORNA SIGNATURE FOR CANCERS, METHODS AND USES RELATED THERETO NATIONAL INSTITUTE OF IMMUNOLOGY (IN) 2023-12-21 US disclosed
US-20230398149-A1 CAR T CELL THERAPY IN PATIENTS WHO HAVE HAD PRIOR ANTI-CANCER ALKYLATOR THERAPY CELGENE CORPORATION (US) 2023-12-14 US disclosed
CN-117159794-A Antibacterial titanium-based material, preparation method and application thereof 广东中科安齿生物科技有限公司 2023-12-05 CN disclosed
WO-2023230548-A1 METHOD FOR PREDICTING RESPONSE TO A T CELL THERAPY CELGENE CORPORATION (US) 2023-11-30 WO disclosed
EP-4272002-A1 USES OF CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELL THERAPIES IN COMBINATION WITH INHIBITORS OF INFLAMMATION-RELATED SOLUBLE FACTORS Celgene Corporation (US) 2023-11-08 EP disclosed
EP-3686285-B1 ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR PEROXIDASE CYANAGEN S R L (IT) 2023-10-11 EP disclosed
US-11761964-B2 Ultra-sensitive chemiluminescent substrates for peroxidase CYANAGEN S.R.L. (IT) 2023-09-19 US disclosed
EP-4241278-A2 CAR T CELL THERAPY IN PATIENTS WHO HAVE HAD PRIOR ANTI-CANCER ALKYLATOR THERAPY Celgene Corporation (US) 2023-09-13 EP disclosed
EP-4223269-A2 USES OF ANTI-BCMA CHIMERIC ANTIGEN RECEPTORS Celgene Corporation (US) 2023-08-09 EP disclosed
US-20230203468-A1 METHODS AND COMPOSITIONS FOR INHIBITING ADAM10 BIOLOGICAL ACTIVITIES Verra Therapeutics, Inc. 2023-06-29 US disclosed
US-20230193202-A1 METHODS FOR MAKING T CELL COMPOSITIONS 2SEVENTY BIO, INC. (US) 2023-06-22 US disclosed
CN-113768870-B Artesunate-containing composition and application thereof 赵鸣 2023-06-20 CN disclosed
US-11633463-B2 BCMA chimeric antigen receptors 2SEVENTY BIO, INC. (US) 2023-04-25 US disclosed
CN-115920018-A Tumor polypeptide vaccine for treating breast cancer and preparation method thereof 张腾飞 2023-04-07 CN disclosed
EP-4143237-A1 KRAS SPECIFIC ANTIBODIES AND USES THEREOF Genentech, Inc. (US) 2023-03-08 EP disclosed
US-20230056815-A1 ANTIBODIES TO FELINE MCDONOUGH SARCOMA (FMS)-LIKE TYROSINE KINASE 3 RECEPTOR LIGAND (FLT3L) AND USES THEREOF FOR TREATING AUTOIMMUNE AND INFLAMMATORY DISEASES VIELA BIO, INC. (US) 2023-02-23 US disclosed
CN-115677821-A Antibacterial peptide and preparation method thereof 韩玉玲 2023-02-03 CN disclosed
US-11560547-B2 Methods of making T cell compositions 2SEVENTY BIO, INC. (US) 2023-01-24 US disclosed
CN-115461375-A KRAS-specific antibodies and uses thereof 基因泰克公司 2022-12-09 CN disclosed
WO-2022221737-A9 T CELL THERAPY IN PATIENTS WHO HAVE HAD PRIOR STEM CELL TRANSPLANT JUNO THERAPEUTICS, INC. (US) 2022-12-08 WO disclosed
US-11512127-B2 Antibodies to Feline McDonough Sarcoma (FMS)-like tyrosine kinase 3 receptor ligand (FLT3L) and uses thereof for treating autoimmune and inflammatory diseases VIELA BIO, INC. (US) 2022-11-29 US disclosed
US-11479755-B2 T cell compositions 2SEVENTY BIO, INC. (US) 2022-10-25 US disclosed
WO-2022221737-A1 T CELL THERAPY IN PATIENTS WHO HAVE HAD PRIOR STEM CELL TRANSPLANT JUNO THERAPEUTICS, INC. (US) 2022-10-20 WO disclosed
CN-111825838-B Polyester amide and preparation method thereof and fiber 上海凯赛生物技术股份有限公司 2022-10-11 CN disclosed
EP-4054622-A1 USES OF ANTI-BCMA CHIMERIC ANTIGEN RECEPTORS Celgene Corporation (US) 2022-09-14 EP disclosed
US-20220273613-A1 COMPOSITION CONTAINING ARTESUNATE ZHAO MING (US) 2022-09-01 US disclosed
US-20220226374-A1 CD79B CHIMERIC ANTIGEN RECEPTORS 2seventy bio, Inc (US) 2022-07-21 US disclosed
US-11382965-B2 BCMA chimeric antigen receptors 2SEVENTY BIO, INC. (US) 2022-07-12 US disclosed
EP-4014996-A1 ANTI-SIALYL TN CHIMERIC ANTIGEN RECEPTORS Helixmith Co., Ltd (KR) 2022-06-22 EP disclosed
WO-2022120160-A1 USES OF CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELL THERAPIES IN COMBINATION WITH INHIBITORS OF INFLAMMATION-RELATED SOLUBLE FACTORS CELGENE CORPORATION (US) 2022-06-09 WO disclosed
US-11351236-B2 BCMA chimeric antigen receptors 2SEVENTY BIO, INC. (US) 2022-06-07 US disclosed
WO-2022098685-A2 CAR T CELL THERAPY IN PATIENTS WHO HAVE HAD PRIOR ANTI-CANCER ALKYLATOR THERAPY CELGENE CORPORATION (US) 2022-05-12 WO disclosed
CN-111978351-B Fire retardant cage-shaped organic silicon phosphoramide compound and preparation method thereof 苏州科技大学 2022-04-26 CN disclosed
CN-111978351-B Fire retardant cage-shaped organic silicon phosphoramide compound and preparation method thereof 苏州科技大学 2022-04-26 CN disclosed
US-20220112308-A1 KRAS SPECIFIC ANTIBODIES AND USES THEREOF GENENTECH, INC. (US) 2022-04-14 US disclosed
EP-3971210-A1 COMPOSITION FOR USE IN THE TREATMENT OF B CELL RELATED CONDITIONS IN A SUBJECT IN NEED THEREOF COMPRISINE AN EFFECTOR CELL COMRISING A BCMA CHIMERIC ANTIGEN RECEPTORS 2seventy bio, Inc. (US) 2022-03-23 EP disclosed
US-11279769-B2 Anti-Sialyl Tn chimeric antigen receptors HELIXMITH CO., LTD (KR) 2022-03-22 US disclosed
US-11279762-B2 Idiotypic antibodies against anti-PD-L1 antibodies and uses thereof GENENTECH, INC. (US) 2022-03-22 US disclosed
CN-114133635-A Oxidation and corrosion resistant plastic 江苏爱唯生物科技有限公司 2022-03-04 CN disclosed
CN-113768870-A Artesunate-containing composition 赵鸣 2021-12-10 CN disclosed
CN-113736298-A Algae inhibiting material and application thereof in agricultural greenhouse film 四川大学 2021-12-03 CN disclosed
CN-109152763-B Artesunate-containing composition 赵鸣 2021-10-01 CN disclosed
CN-107951835-B Enalapril maleate preparation and application thereof 湖南千金湘江药业股份有限公司 2021-08-24 CN disclosed
CN-110218778-B PCR reaction system, reagent, kit and PCR method 珠海宝锐生物科技有限公司 2021-05-28 CN disclosed
CN-112805351-A Compositions comprising 1, 2-dichloro-1, 2-difluoroethylene for use in heat transfer applications 科慕埃弗西有限公司 2021-05-14 CN disclosed
CN-110229189-B Preparation method of tri-oxalic acid phosphate 上海如鲲新材料有限公司 2021-05-07 CN disclosed
US-10987338-B2 Composition containing artesunate ZHAO MING (US) 2021-04-27 US disclosed
CN-112661791-A Preparation method of lithium difluorobis (oxalate) phosphate 多氟多化工股份有限公司 2021-04-16 CN disclosed
CN-111978351-A Fire retardant cage-shaped organic silicon phosphoramide compound and preparation method thereof 苏州科技大学 2020-11-24 CN disclosed
CN-111978351-A Fire retardant cage-shaped organic silicon phosphoramide compound and preparation method thereof 苏州科技大学 2020-11-24 CN disclosed
CN-111925390-A Preparation method of tris (butoxyethyl) phosphate 太仓康源化建医药有限公司 2020-11-13 CN disclosed
EP-3684835-A1 COLOUR-STABLE CURING COMPOSITIONS CONTAINING POLYISOCYANATE (CYCLO)ALIPHATIC DIISOCYANATES BASF SE (DE) 2020-07-29 EP disclosed
EP-3684833-A1 METHOD FOR PRODUCING POLYISOCYANATES OF (CYCLO)ALIPHATIC DIISOCYANATES WHICH ARE FLOCCULATION-STABLE IN SOLVENTS BASF SE (DE) 2020-07-29 EP disclosed
US-10471042-B2 Composition containing artesunate ZHAO MING (US) 2019-11-12 US disclosed
CN-110218778-A PCR reaction system, reagent, kit and PCR method 珠海宝锐生物科技有限公司 2019-09-10 CN disclosed
CN-109608497-A A kind of preparation method of fosfomycin trometamol 科大华采(武汉)生物科技股份有限公司 2019-04-12 CN disclosed
US-20190029996-A1 composition containing artesunate ZHAO MING (US) 2019-01-31 US disclosed
EP-3402479-A1 COMPOSITION CONTAINING ARTESUNATE Zhao, Ming (US) 2018-11-21 EP disclosed
US-9840535-B2 Method of recovering peptide and method of detecting peptide SYSMEX CORPORATION (JP) 2017-12-12 US disclosed
WO-2017124045-A1 COMPOSITION CONTAINING ARTESUNATE ZHAO MING (US) 2017-07-20 WO disclosed
US-9624263-B2 Method of recovering peptide and method of detecting peptide SYSMEX CORPORATION (JP) 2017-04-18 US disclosed
US-9620354-B2 Method for manufacturing semiconductor substrate with diffusion agent composition TOKYO OHKA KOGYO CO., LTD. (JP) 2017-04-11 US disclosed
US-20160314975-A1 DIFFUSION AGENT COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2016-10-27 US disclosed
EP-2902407-B1 Method of recovering peptide SYSMEX CORP (JP) 2016-04-13 EP disclosed
US-20160099149-A1 METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE TOKYO OHKA KOGYO CO., LTD. (JP) 2016-04-07 US disclosed
EP-2902408-B1 Method of recovering peptide SYSMEX CORP (JP) 2016-04-06 EP disclosed
CN-105008343-A Benzothiophene derivatives and compositions thereof as selective estrogen receptor degraders NOVARTIS AG 2015-10-28 CN disclosed
CN-103189361-B Estrogenic agents and uses thereof ARAGON PHARMACEUTICALS, INC. (US) 2015-09-30 CN disclosed
CN-104086592-B A kind of preparation method of fosfomycin trometamol GUILIN HUAXIN PHARMACEUTICAL Co.,Ltd. (CN) 2015-09-09 CN disclosed
EP-2902407-A1 Method of recovering peptide SYSMEX CORPORATION (JP) 2015-08-05 EP disclosed
EP-2902408-A1 Method of recovering peptide SYSMEX CORPORATION (JP) 2015-08-05 EP disclosed
US-20150210736-A1 METHOD OF RECOVERING PEPTIDE AND METHOD OF DETETING PEPTIDE SYSMEX CORPORATION (JP) 2015-07-30 US disclosed
US-20150203533-A1 METHOD OF RECOVERING PEPTIDE AND METHOD OF DETECTING PEPTIDE SYSMEX CORPORATION (JP) 2015-07-23 US disclosed
CN-102807586-B Preparation method of fosfomycin amine salt NORTHEAST PHARMACEUTICAL GROUP CO LTD 2015-05-13 CN disclosed
CN-104220426-A Estrogen receptor modulators and uses thereof SERAGON PHARMACEUTICALS INC 2014-12-17 CN disclosed
CN-101663295-B Aminopyrimidines useful as inhibitors of protein kinases VERTEX PHARMA 2014-11-05 CN disclosed
CN-104114551-A Fluorinated estrogen receptor modulators and uses thereof ARAGON PHARMACEUTICALS INC 2014-10-22 CN disclosed
CN-104086592-A Preparation method of fosfomycin tromethamine GUILIN HUAXIN PHARMACEUTICAL CO LTD 2014-10-08 CN disclosed
CN-102838664-B Gamma-aminobutyric acid transportprotein as well as coding gene and application of gamma-aminobutyric acid transportprotein CHINESE ACAD INST MICROBIOLOGY 2014-06-04 CN disclosed
CN-103842563-A Method of protein display AFFINITY BIOSCIENCES PTY LTD 2014-06-04 CN disclosed
CN-103724322-A Androgen receptor modulators and uses thereof ARAGON PHARMACEUTICALS INC 2014-04-16 CN disclosed
CN-102321556-B Aeromonas and application of aeromonas in biotransformation of (R)-alpha-hydroxyphenylacetic acid UNIV JIMEI 2013-11-27 CN disclosed
CN-101790532-B Preparation method of 5-fluoro-1H-pyrazolo [3,4-b ] pyridine-3-amine and derivatives thereof VERTEX PHARMA 2013-11-20 CN disclosed
CN-101668760-B Aminopyrimidines useful as inhibitors of protein kinases VERTEX PHARMA 2013-07-24 CN disclosed
CN-103189361-A Estrogen receptor modulators and use thereof ARAGON PHARMACEUTICALS INC 2013-07-03 CN disclosed
CN-103145702-A Aminopyrimidines useful as kinase inhibitors VERTEX PHARMA 2013-06-12 CN disclosed
US-20130098775-A1 Glucose biosensor with improved shelf life NOVA BIOMEDICAL CORPORATION (US) 2013-04-25 US disclosed
WO-2013059534-A1 GLUCOSE BIOSENSOR WITH IMPROVED SHELF LIFE NOVA BIOMEDICAL CORPORATION (US) 2013-04-25 WO disclosed
CN-101316597-B Aminopyrimidines useful as kinase inhibitors VERTEX PHARMA 2013-04-17 CN disclosed
CN-102939287-A Estrogen receptor modulators and uses thereof ARAGON PHARMACEUTICALS INC 2013-02-20 CN disclosed
CN-102884057-A Androgen receptor modulators and uses thereof ARAGON PHARMACEUTICALS INC 2013-01-16 CN disclosed
CN-101316843-B Aminopyrimidines useful as kinase inhibitors VERTEX PHARMA 2013-01-02 CN disclosed
CN-102838664-A Gamma-aminobutyric acid transportprotein as well as coding gene and application of gamma-aminobutyric acid transportprotein CHINESE ACAD INST MICROBIOLOGY 2012-12-26 CN disclosed
CN-101098872-B Pyrrolopyrazines and pyrazolopyrazines useful as protein kinase inhibitors VERTEX PHARMA 2012-09-05 CN disclosed
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CN-102399275-A Gamma-aminobutyric acid transport protein and coding gene and application thereof CHINESE ACAD INST MICROBIOLOGY 2012-04-04 CN disclosed
CN-102321556-A Aeromonas and application of aeromonas in biotransformation of (R)-alpha-hydroxyphenylacetic acid UNIV JIMEI 2012-01-18 CN disclosed
CN-102300862-A Compounds useful as inhibitors of ATR kinase 2011-12-28 CN disclosed
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CN-1934113-B Compositions useful as protein kinase inhibitors VERTEX PHARMA CO LTD 2011-11-09 CN disclosed
US-8003076-B2 Methods for conducting metabolic analyses TARGET DISCOVERY, INC. (US) 2011-08-23 US disclosed
CN-101094853-B Pyrazolo [1,5-a ] pyrimidines useful as protein kinase inhibitors VERTEX PHARMA CO LTD 2011-07-13 CN disclosed
EP-2293056-A2 A method for analysing a metabolic pathway Target Discovery, Inc. (US) 2011-03-09 EP disclosed
CN-101932583-A Pyrazolo [1,5-a] pyrimidines useful as jak2 inhibitors VERTEX PHARMA 2010-12-29 CN disclosed
CN-1812973-B Indazole compounds useful as protein kinase inhibitors VERTEX PHARMA CO LTD 2010-12-22 CN disclosed
CN-101848909-A Pyrrolo [3,2-C ] pyridines useful as protein kinase inhibitors VERTEX PHARMA 2010-09-29 CN disclosed
CN-101824043-A The composition that can be used as kinases inhibitor VERTEX PHARMA 2010-09-08 CN disclosed
CN-101790532-A Preparation method of 5-fluoro-1H-pyrazolo [3,4-b ] pyridine-3-amine and derivatives thereof VERTEX PHARMA 2010-07-28 CN disclosed
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CN-101495474-A Thiophene-carboxamides useful as inhibitors of protein kinases VERTEX PHARMA (US) 2009-07-29 CN disclosed
CN-101484447-A Thiophene-carboxamides useful as inhibitors of protein kinases VERTEX PHARMA (US) 2009-07-15 CN disclosed
CN-100500636-C Method of extracting amygdalic acid using strong alkali anion exchange resin UNIV FUZHOU (CN) 2009-06-17 CN disclosed
CN-101460466-A Thiazoles, imidazoles, and pyrazoles useful as inhibitors of protein kinases VERTEX PHARMA (US) 2009-06-17 CN disclosed
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CN-101321530-A Aminopyrimidines useful as kinase inhibitors VERTEX PHARMA (US) 2008-12-10 CN disclosed
CN-101316597-A Aminopyrimidines useful as kinase inhibitors VERTEX PHARMA (US) 2008-12-03 CN disclosed
CN-101316843-A Aminopyrimidines useful as kinase inhibitors VERTEX PHARMA (US) 2008-12-03 CN disclosed
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CN-101111479-A Pyridones useful as kinase inhibitors VERTEX PHARMA (US) 2008-01-23 CN disclosed
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CN-101094853-A Pyrazolo [1, 5-a ] pyrimidines useful as protein kinase inhibitors VERTEX PHARMA (US) 2007-12-26 CN disclosed
CN-100351251-C Indolylmaleimide derivatives NOVARTIS AG (CH) 2007-11-28 CN disclosed
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CN-1948262-A Method of extracting amygdalic acid using strong alkali anion exchange resin UNIV FUZHOU (CN) 2007-04-18 CN disclosed
CN-1944382-A Method for separating and purifying mandelic acid using wealk alkali anion exchange agent UNIV FUZHOU (CN) 2007-04-11 CN disclosed
CN-1934113-A Compositions useful as protein kinase inhibitors VERTEX PHARMA (US) 2007-03-21 CN disclosed
CN-1894258-A Compositions useful as protein kinase inhibitors VERTEX PHARMA (US) 2007-01-10 CN disclosed
CN-1262662-C Chimeric expression promoters originating from commelina yellow mottle virus and cassava vein mosaic virus MERISTEM THERAPEUTICS (FR) 2006-07-05 CN disclosed
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CN-1214103-C Detection of micro-organisms FLUID TECHNOLOGIES LTD (GB) 2005-08-10 CN disclosed
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CN-1639153-A Indolylmaleimide derivatives NOVARTIS AG (CH) 2005-07-13 CN disclosed
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CN-1190431-C Production method of (per-rac) alpha tocopherol DSM IP N V (NL) 2005-02-23 CN disclosed
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CN-1570135-A Homotype cysteine detecting method adopting micromolecule trapping technology BEIJING JIUQIANG BIOTECHNOLOGY (CN) 2005-01-26 CN disclosed
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CN-1523112-A Tetracycline-regulated transcriptional modulators BASF 2004-08-25 CN disclosed
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CN-1365977-A Production method of (per-rac) alpha tocopherol ROCHE VITAMIN AG (CH) 2002-08-28 CN disclosed
CN-1353763-A Chimeric expression promoter derived from dayflower yellow mottle virus and cassava vein mosaic virus MERISTEM THERAPEUTICS (FR) 2002-06-12 CN disclosed
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CN-1228125-A Universal test systems and method for identifying multiple families of microorganisms DADE MICROSCAN INC (US) 1999-09-08 CN disclosed
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JP-H09154571-A SERUM-FREE CULTURE MEDIUM FOR PRODUCING VIRUS KURABO IND LTD 1997-06-17 JP disclosed
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EP-0515089-B1 Ink compositions having decreased drying times XEROX CORP (US) 1996-11-13 EP disclosed
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CN-1119457-A Bone stimulating factor OSTEOPHARM LTD (CA) 1996-03-27 CN disclosed
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EP-0304151-B1 Measurement of calcium ions INSTRUMENTATION LAB SPA (IT) 1993-12-15 EP disclosed
EP-0515089-A1 Ink compositions having decreased drying times XEROX CORPORATION (US) 1992-11-25 EP disclosed
EP-0506922-A1 INDIRECT POTENTIOMETRIC METHOD AND DILUENT FOR ANALYSIS OF LITHIUM. BECKMAN INSTRUMENTS INC (US) 1992-10-07 EP disclosed
EP-0503297-A1 GLIA activating factor and its production TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-16 EP disclosed
US-5110742-A Quantitative analysis of clinical sample; electrodes selective for lithium and for interfering ion BECKMAN INSTRUMENTS, INC. (US) 1992-05-05 US disclosed
US-5110742-A Quantitative analysis of clinical sample; electrodes selective for lithium and for interfering ion BECKMAN INSTRUMENTS, INC. (US) 1992-05-05 US disclosed
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EP-0304151-A2 Measurement of calcium ions INSTRUMENTATION LABORATORY S.p.A. (IT) 1989-02-22 EP disclosed
EP-0304151-A2 Measurement of calcium ions INSTRUMENTATION LABORATORY S.p.A. (IT) 1989-02-22 EP disclosed
EP-0029765-B1 CREATININE IMINOHYDROLASE FREE FROM UREASE ACTIVITY, METHODS OF PREPARATION AND USE, AND ASSAY COMPOSITIONS AND ANALYTICAL ELEMENTS CONTAINING SAME EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-05-29 EP disclosed
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Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250295771-A1 METHODS AND USES RELATED TO T CELL THERAPY AND PRODUCTION OF SAME CD2, CD74, PBK LMNA 1902/4885MEN1 4170/4885KMT2A 358/4885
US-20240342299-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 LMNA 4156/4885MEN1 2331/4885KMT2A 4385/4885
US-20220273613-A1 COMPOSITION CONTAINING ARTESUNATE GLS2, GYS2, ACE LMNA 927/4885MEN1 4173/4885KMT2A 2486/4885
US-20250009710-A1 COMPOSITION CONTAINING ARTESUNATE MTAP, PDF, GLS2 LMNA 1482/4885MEN1 4110/4885KMT2A 3120/4885
US-20090010915-A1 Methods for Conducting Metabolic Analyses PC, FAH, CYP27A1 LMNA 2081/4885MEN1 866/4885KMT2A 3864/4885
US-20250064954-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 LMNA 4156/4885MEN1 2331/4885KMT2A 4385/4885
US-10987338-B2 Composition containing artesunate MTAP, PDF, GLS2 LMNA 1482/4885MEN1 4110/4885KMT2A 3120/4885
US-10471042-B2 Composition containing artesunate MTAP, PDF, GLS2 LMNA 1482/4885MEN1 4110/4885KMT2A 3120/4885
US-12083096-B2 Composition containing artesunate GLS2, GYS2, ACE LMNA 927/4885MEN1 4173/4885KMT2A 2486/4885
US-20260115287-A1 T CELL THERAPY IN PATIENTS WHO HAVE HAD PRIOR STEM CELL TRANSPLANT PBK, ICOS, CD47 LMNA 2799/4885MEN1 896/4885KMT2A 234/4885
US-20220112308-A1 KRAS SPECIFIC ANTIBODIES AND USES THEREOF KRAS, NRAS, HRAS LMNA 4157/4885MEN1 3282/4885KMT2A 2922/4885
US-20190029996-A1 composition containing artesunate MTAP, PDF, GLS2 LMNA 1482/4885MEN1 4110/4885KMT2A 3120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.