Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41154 | 0.95 | — | — | |
| SCHEMBL28210644 | 0.91 | — | — | |
| SCHEMBL28072631 | 0.91 | — | — | |
| Ammonia Solution, Strong SCHEMBL27304734 | 0.91 | — | — | |
| Bromide SCHEMBL1730618 | 0.91 | — | — | |
| Hydrogen Sulfide SCHEMBL87829 | 0.91 | — | — | |
| Methyl Alcohol SCHEMBL7530432 | 0.91 | — | — | |
| SCHEMBL27826950 | 0.91 | — | — | |
| Dimethylamine SCHEMBL28870842 | 0.91 | — | — | |
| SCHEMBL28196109 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267121-A | BY REACTION OF 2,2-DIMETHYL-4-CYANO-BUTYRALDOXIME WITH METHYL CARBAMIC ACID CHLORIDE IN THE PRESENCE OF A TERTIARY AMINE | BASF AKTIENGESELLSCHAFT (DE) | 1981-05-12 | — | — | US | claimed |
| US-3956089-A | Process for producing N-chlorocarbonyl isocyanide dichloride | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | claimed |
| JP-6157448-A | — | — | None | — | — | JP | disclosed |
| CN-113271939-B | Imidazole tetrazine compounds | 伊利诺伊大学董事会 | 2025-03-07 | — | — | CN | disclosed |
| CN-112521368-B | Triazole N-linked carbamoyl cyclohexyl acid as LPA antagonists | 百时美施贵宝公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2023210792-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING OXIME GROUP, AGRICULTURAL/HORTICULTURAL HERBICIDE CONTAINING SAID COMPOUND, AND USE OF BOTH OF FOREGOING | 日本農薬株式会社 | 2023-11-02 | — | — | WO | disclosed |
| CN-116472292-A | Modified proteins and protein degrading agents | 上海睿跃生物科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| EP-3458069-B1 | PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF | MERSANA THERAPEUTICS INC (US) | 2023-07-05 | — | — | EP | disclosed |
| CN-111100624-B | Low-corrosion self-gas-generation energy-increasing fracturing fluid and preparation method thereof | 中国石油大学(华东) | 2022-04-26 | — | — | CN | disclosed |
| CN-112521368-A | Triazole N-linked carbamoylcyclohexanoic acids as LPA antagonists | 百时美施贵宝公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-112189010-A | Triazole N-linked carbamoylcyclohexanoic acids as LPA antagonists | 百时美施贵宝公司 | 2021-01-05 | — | — | CN | disclosed |
| US-4195031-A | Process for the continuous production of monoisocyanates | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-25 | — | — | US | disclosed |
| US-4195032-A | Process for continuously working up solutions of the type accumulating in the phosgenation of monoamines | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-25 | — | — | US | disclosed |
| US-4162263-A | Manufacture of aliphatic or cycloaliphatic isocyanates | BASF AKTIENGESELLSCHAFT (DE) | 1979-07-24 | — | — | US | disclosed |
| US-4146550-A | REACTION OF CARBAMIC ACID CHLORIDE WITH ACTIVE HYDROGEN COMPOUND, DECOMPOSITION | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-27 | — | — | US | disclosed |
| US-4051165-A | Preparation of biuret polyisocyanates | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3969388-A | Manufacture of alkylisocyanates | BASF AKTIENGESELLSCHAFT (DT) | 1976-07-13 | — | — | US | disclosed |
| US-3969389-A | Manufacture of aliphatic isocyanates | BASF AKTIENGESELLSCHAFT (DT) | 1976-07-13 | — | — | US | disclosed |
| US-3956089-A | Process for producing N-chlorocarbonyl isocyanide dichloride | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |
| US-3956089-A | Process for producing N-chlorocarbonyl isocyanide dichloride | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |