Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1695676 | 0.77 | — | — | |
| SCHEMBL15429244 | 0.77 | — | — | |
| 2-Bromoethanol SCHEMBL4943481 | 0.73 | TSHR (0.30) | — | |
| SCHEMBL2502585 | 0.72 | — | — | |
| SCHEMBL15161898 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL31112620 | 0.72 | — | — | |
| SCHEMBL15915168 | 0.70 | — | — | |
| SCHEMBL15429243 | 0.70 | — | — | |
| SCHEMBL15429242 | 0.70 | — | — | |
| SCHEMBL15915876 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015378-A1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (KY) | 2026-01-15 | — | — | US | disclosed |
| US-12258368-B2 | Disulfide-linked reversible terminators | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (KY) | 2025-03-25 | — | — | US | disclosed |
| US-20220389049-A1 | REVERSIBLE TERMINATORS FOR DNA SEQUENCING AND METHODS OF USING THE SAME | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (VG) | 2022-12-08 | — | — | US | disclosed |
| US-20220048940-A1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (KY) | 2022-02-17 | — | — | US | disclosed |
| US-11180522-B2 | Disulfide-linked reversible terminators | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (KY) | 2021-11-23 | — | — | US | disclosed |
| EP-3856753-A1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | Centrillion Technology Holdings Corporation (KY) | 2021-08-04 | — | — | EP | disclosed |
| WO-2021067970-A1 | REVERSIBLE TERMINATORS FOR DNA SEQUENCING AND METHODS OF USING THE SAME | CENTRILLION TECHNOLOGIES, INC. (US) | 2021-04-08 | — | — | WO | disclosed |
| WO-2020069424-A1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | CENTRILLION TECHNOLOGIES, INC. (US) | 2020-04-02 | — | — | WO | disclosed |
| EP-3091026-B1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | CENTRILLION TECH HOLDINGS CORP (KY) | 2019-02-20 | — | — | EP | disclosed |
| US-10059986-B2 | Reversible terminator molecules and methods of their use | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (US) | 2018-08-28 | — | — | US | disclosed |
| US-20170218441-A1 | REVERSIBLE TERMINATOR MOLECULES AND METHODS OF THEIR USE | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (US) | 2017-08-03 | — | — | US | disclosed |
| US-9650406-B2 | Reversible terminator molecules and methods of their use | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (US) | 2017-05-16 | — | — | US | disclosed |
| US-20160355541-A1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (KY) | 2016-12-08 | — | — | US | disclosed |
| WO-2016182984-A1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (KY) | 2016-11-17 | — | — | WO | disclosed |
| EP-3091026-A1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | Centrillion Technology Holdings Corporation (KY) | 2016-11-09 | — | — | EP | disclosed |
| US-20140242579-A1 | REVERSIBLE TERMINATOR MOLECULES AND METHODS OF THEIR USE | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION | 2014-08-28 | — | — | US | disclosed |