Hydrochloric Acid

Hydrochloric Acid

SCHEMBL163264

Cl.NC(F)(F)CF

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL215193 0.95
Methane SCHEMBL29008800 0.91
Hydrochloric Acid SCHEMBL5256487 0.73
Norflurane SCHEMBL6464542 0.70
Hydrochloric Acid SCHEMBL20425202 0.70
Hydrochloric Acid SCHEMBL72995 0.70
Hydrochloric Acid SCHEMBL9376252 0.68
Hydrochloric Acid SCHEMBL10799311 0.68
Hydrochloric Acid SCHEMBL5255990 0.67
SCHEMBL4060203 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117750862-A Perovskite battery and preparation method thereof 极电光能有限公司 2024-03-22 CN claimed
CN-116102446-A Simple method for preparing 2-amino-N- (2, 2-trifluoroethyl) acetamide 岳阳市康利医药化工有限公司 2023-05-12 CN claimed
CN-115785015-A Synthetic method of sodium fluridide 天和药业股份有限公司 2023-03-14 CN claimed
CN-115536541-A Synthesis method of common intermediate of flurradine and afurane 湖北美天生物科技股份有限公司 2022-12-30 CN claimed
CN-114414678-A Analysis method for related impurities of isoxazoline veterinary drug intermediate ammonium salt 丽珠集团新北江制药股份有限公司 2022-04-29 CN claimed
CN-106892936-B A kind of synthetic method of second level trifluoromethyl propargyl ethanol 合肥工业大学 2019-07-19 CN claimed
CN-109485683-A Fluorine-containing serial avermectin derivatives of one kind and preparation method thereof 齐鲁晟华制药有限公司 2019-03-19 CN claimed
CN-108997145-A A kind of method of ferriporphyrin catalysis aromatic secondary amine trifluoroethyl 沅江华龙催化科技有限公司 2018-12-14 CN claimed
CN-108997144-A A kind of method of ferriporphyrin catalysis aromatic primary amine trifluoroethyl 沅江华龙催化科技有限公司 2018-12-14 CN claimed
CN-105801428-B A kind of preparation method of trifluoroethylamine hydrochloride 浙江蓝天环保高科技股份有限公司 2018-07-03 CN claimed
CN-106892936-A A kind of synthetic method of two grades of trifluoromethyl propargyl ethanols 合肥工业大学 2017-06-27 CN claimed
CN-106146385-A A kind of synthetic method of triglyceride transfer protein enzyme inhibitor 天津药物研究院有限公司 2016-11-23 CN claimed
US-12582718-B2 Integrin targeting ligands and uses thereof Arrowhead Pharmaceuticals, Inc. (US) 2026-03-24 US disclosed
US-20260042774-A1 CAMPTOTHECIN-7-ETHYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF HANGZHOU ADCORIS BIOPHARMA CO LTD (CN) 2026-02-12 US disclosed
US-12545701-B2 C4-modified oleanolic acid derivatives for inhibition of IL-17 and other uses REATA PHARMACEUTICALS, INC. (US) 2026-02-10 US disclosed
CN-121405706-A Synthesis method of Marpatinib and intermediate Up-3 thereof 常州亚邦制药有限公司 2026-01-27 CN disclosed
EP-0294847-A1 Fluorine-containing nitroazole derivatives and radiosensitizer comprising the same KYOTO UNIVERSITY (JP) 1988-12-14 EP disclosed
US-4784987-A GROWTH REGULATORS IN FISH AND AMPHIBIANS THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1988-11-15 US disclosed
EP-0274916-A2 GRF analogs THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1988-07-20 EP disclosed
US-3960949-A DIABETES SCHERING AKTIENGESELLSCHAFT (DT) 1976-06-01 US disclosed