Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A known ✓ | P28223 | 2/20 | 0.36 |
| ▸ | HTR6 known ✓ | P50406 | 1/20 | 0.36 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 2/20 | 0.30 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 known ✓ | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.30 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.30 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C known ✓ | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.30 |
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.30 |
| ▸ | HTR2B known ✓ | P41595 | 1/20 | 0.30 |
| ▸ | CACNA1B known ✓ | Q00975 | 1/20 | 0.30 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.30 |
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.30 |
| ▸ | RET known ✓ | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8522504 | 1.00 | HTR2A (0.36) | HTR2AHTR6KDM4EMEN1PMP22 | |
| Hydrochloric Acid SCHEMBL8522502 | 1.00 | HTR2A (0.36) | HTR2AHTR6KDM4EMEN1PMP22 | |
| Hydrochloric Acid SCHEMBL7825405 | 0.98 | HTR2A (0.35) | HTR2AHTR6KDM4EMEN1PMP22 | |
| SCHEMBL29393845 | 0.98 | HTR2A (0.38) | HTR2AHTR6KDM4EMEN1PMP22 | |
| SCHEMBL2364504 | 0.98 | HTR2A (0.38) | HTR2AHTR6KDM4EMEN1PMP22 | |
| Bromide SCHEMBL11875417 | 0.96 | HTR2A (0.36) | HTR2AHTR6KDM4ESIGMAR1BRD4 | |
| Fluoride SCHEMBL29462970 | 0.96 | HTR2A (0.36) | HTR2AHTR6KDM4ESIGMAR1BRD4 | |
| Fluoride SCHEMBL178212 | 0.96 | HTR2A (0.36) | HTR2AHTR6KDM4ESIGMAR1BRD4 | |
| Fluoride SCHEMBL5067176 | 0.96 | HTR2A (0.36) | HTR2AHTR6KDM4ESIGMAR1BRD4 | |
| Hydrochloric Acid SCHEMBL7825409 | 0.94 | HTR2A (0.35) | HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12173102-B2 | Reactor system for producing modacrylic polymer and a production method thereof | AKSA AKRILIK KIMYA SANAYII ANONIM SIRKETI (TR) | 2024-12-24 | — | — | US | claimed |
| US-11225757-B2 | Barrier laminate with excellent barrier properties against moisture and gas and method of manufacturing same | HANSOL PAPER CO., LTD. (KR) | 2022-01-18 | — | — | US | claimed |
| EP-3922770-A1 | BARRIER LAMINATE WITH EXCELLENT BARRIER PROPERTIES AGAINST MOISTURE AND GAS AND METHOD OF MANUFACTURING SAME | Hansol Paper Co., Ltd. (KR) | 2021-12-15 | — | — | EP | claimed |
| US-20200291580-A1 | BARRIER LAMINATE WITH EXCELLENT BARRIER PROPERTIES AGAINST MOISTURE AND GAS AND METHOD OF MANUFACTURING SAME | HANSOL PAPER CO., LTD. (KR) | 2020-09-17 | — | — | US | claimed |
| EP-3620576-A1 | BARRIER LAMINATE HAVING EXCELLENT MOISTURE AND GAS BARRIER PROPERTIES, AND METHOD FOR PRODUCING SAME | Hansol Paper Co., Ltd. (KR) | 2020-03-11 | — | — | EP | claimed |
| EP-1896530-A4 | THERMOPLASTIC POLYMER COMPOSITIONS INCLUDING SILICA-CONTAINING NUCLEATING AGENTS | BEAULIEU GROUP LLC (US) | 2009-08-26 | — | — | EP | claimed |
| EP-1896530-A2 | THERMOPLASTIC POLYMER COMPOSITIONS INCLUDING SILICA-CONTAINING NUCLEATING AGENTS | Beaulieu Group, LLC (US) | 2008-03-12 | — | — | EP | claimed |
| WO-2006135809-A2 | THERMOPLASTIC POLYMER COMPOSITIONS INCLUDING SILICA-CONTAINING NUCLEATING AGENTS | BEAULIEU GROUP, LLC D/B/A BEAULIEU OF AMERICA (US) | 2006-12-21 | — | — | WO | claimed |
| US-20060281851-A1 | THERMOPLASTIC POLYMER COMPOSITIONS INCLUDING SILICA-CONTAINING NUCLEATING AGENTS | BRANCH BANKING AND TRUST COMPANY, AS ADMINISTRATIVE AGENT | 2006-12-14 | — | — | US | claimed |
| US-4795475-A | Prosthesis utilizing salt-forming oxyacids for bone fixation | WALKER MICHAEL M (US) | 1989-01-03 | — | — | US | claimed |
| JP-61078887-A | — | — | None | — | — | JP | disclosed |
| JP-11154628-A | — | — | None | — | — | JP | disclosed |
| US-12069927-B2 | Display apparatus including quantum dot | SAMSUNG DISPLAY CO., LTD. (KR) | 2024-08-20 | — | — | US | disclosed |
| US-11577863-B2 | Compact system for packaging microfibrillated cellulose | BORREGAARD AS (NO) | 2023-02-14 | — | — | US | disclosed |
| US-20220165802-A1 | DISPLAY APPARATUS | SAMSUNG DISPLAY CO., LTD. (KR) | 2022-05-26 | — | — | US | disclosed |
| US-4720345-A | Semipermeable membranes of modified styrene-based polymers, process for their manufacture and their use | ALIGENA AG (CH) | 1988-01-19 | — | — | US | disclosed |
| JP-S6178887-A | HEAT-PEELABLE SELF-ADHESIVE SHEET | SHINKO KAGAKU KOGYO KK | 1986-04-22 | — | — | JP | disclosed |
| EP-0005866-B1 | AN OXYGENATOR | TERUMO CORPORATION (JP) | 1981-08-26 | — | — | EP | disclosed |
| US-4147687-A | Formed objects of coal flyash and methods of making the same | DONNELL HUGH T O | 1979-04-03 | — | — | US | disclosed |
| US-3940376-A | Permanently antistatic shaped structures of acrylonitrile polymers | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-24 | — | — | US | disclosed |