Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26382115 | 0.82 | HSD11B1 (0.34) | KMT2AHSD11B1 | |
| SCHEMBL2614240 | 0.78 | KMT2A (0.31) | KMT2A | |
| SCHEMBL27419998 | 0.78 | KMT2A (0.33) | KMT2A | |
| SCHEMBL10072131 | 0.78 | KMT2A (0.31) | KMT2AKDM4E | |
| SCHEMBL13142134 | 0.78 | — | — | |
| SCHEMBL26508547 | 0.78 | CA12 (0.43) | — | |
| SCHEMBL31158128 | 0.78 | DRD3 (0.37) | KDM4E | |
| SCHEMBL15498540 | 0.76 | KMT2A (0.30) | KMT2A | |
| SCHEMBL14375590 | 0.76 | CHRM1 (0.38) | KMT2A | |
| SCHEMBL19091682 | 0.76 | RIPK1 (0.37) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024232563-A1 | GROUP 14 ORGANOMETALLIC COMPOUND, PREPARATION METHOD THEREFOR, AND METHOD FOR FORMING THIN FILM BY USING SAME | 한국화학연구원 | 2024-11-14 | — | — | WO | disclosed |
| US-20230348360-A1 | Amino Lipid and Preparation Method and Application Thereof | SHENZHEN MAGICRNA BIOTECHNOLOGY CO LTD (CN) | 2023-11-02 | — | — | US | disclosed |
| US-20230310551-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME LLC (US) | 2023-10-05 | — | — | US | disclosed |
| US-20230158141-A1 | Conjugates of Biomolecule and Use Thereof | YAFEI SHANGHAI BIOLOG MEDICINE SCIENCE & TECHNOLOG (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20230131402-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | APTINYX INC (US) | 2023-04-27 | — | — | US | disclosed |
| US-20230043863-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2023-02-09 | — | — | US | disclosed |
| US-10882883-B2 | Derivatives of amphotericin B | SFUNGA THERAPEUTICS, INC. (US) | 2021-01-05 | — | — | US | disclosed |
| US-20200262858-A1 | DERIVATIVES OF AMPHOTERICIN B | ELION THERAPEUTICS, INC. | 2020-08-20 | — | — | US | disclosed |
| US-10669252-B2 | Benzazepine derivative, preparation method, pharmaceutical composition and use thereof | Shanghai De Novo Pharmatech Co., Ltd. (CN) | 2020-06-02 | — | — | US | disclosed |
| US-20190276489-A1 | PROGESTERONE ANALOGS AND USES RELATED THERETO | EMORY UNIVERSITY | 2019-09-12 | — | — | US | disclosed |
| US-20080045496-A1 | PYRROLOTRIAZINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2008-02-21 | — | — | US | disclosed |
| US-20080027100-A1 | Functionally selective alpha2C adrenoreceptor agonists | SCHERING CORPORATION AND PHARMACOPEIA, INC. | 2008-01-31 | — | — | US | disclosed |
| US-7312359-B2 | 2-(5-Benzenesulfonyl-indan-1-yl)-ethylamine, used as selective serotonin receptor antagonists for treatment of nervous system and gastrointestinal disorders | ROCHE PALO ALTO LLC (US) | 2007-12-25 | — | — | US | disclosed |
| US-20070293526-A1 | Arylsulfonyl naphthalene derivatives and uses thereof | ROCHE PALO ALTO LLC | 2007-12-20 | — | — | US | disclosed |
| US-20070244055-A1 | Conjugates useful in the treatment of prostate cancer | BRADY STEPHEN F | 2007-10-18 | — | — | US | disclosed |
| US-20070155776-A1 | THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS | ABBVIE INC. | 2007-07-05 | — | — | US | disclosed |
| US-20070129309-A1 | Conjugates useful in the treatment of prostate cancer | BRADY STEPHEN F | 2007-06-07 | — | — | US | disclosed |
| US-20070099872-A1 | Functionally selective alpha2C adrenoreceptor agonists | SCHERING CORPORATION | 2007-05-03 | — | — | US | disclosed |
| US-7202363-B2 | Thienopyridine and furopyridine kinase inhibitors | ABBOTT LABORATORIES (US) | 2007-04-10 | — | — | US | disclosed |
| US-20070021350-A1 | Conjugates useful in the treatment of prostate cancer | BRADY STEPHEN F | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (17 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348360-A1 | Amino Lipid and Preparation Method and Application Thereof | SLC7A1, SLC7A5, SLC43A1 | KMT2A 1095/4885HSD11B1 4172/4885KDM4E 643/4885 |
| US-20070293526-A1 | Arylsulfonyl naphthalene derivatives and uses thereof | ARSA, AR, SULT2A1 | KMT2A 879/4885HSD11B1 976/4885KDM4E 1655/4885 |
| US-20230158141-A1 | Conjugates of Biomolecule and Use Thereof | CD47, FCGR2A, CD40 | KMT2A 2284/4885HSD11B1 4492/4885KDM4E 2983/4885 |
| US-10882883-B2 | Derivatives of amphotericin B | C9, ERG28, AMPD3 | KMT2A 4170/4885HSD11B1 2063/4885KDM4E 2646/4885 |
| US-10669252-B2 | Benzazepine derivative, preparation method, pharmaceutical composition and use thereof | TLR8, TLR1, TLR5 | KMT2A 751/4885HSD11B1 1367/4885KDM4E 1342/4885 |
| US-20070129309-A1 | Conjugates useful in the treatment of prostate cancer | BPHL, KLK3, DNPEP | KMT2A 154/4885HSD11B1 1469/4885KDM4E 1171/4885 |
| US-20230043863-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | WEE2, WEE1, RORB | KMT2A 2361/4885HSD11B1 91/4885KDM4E 2064/4885 |
| US-20080027100-A1 | Functionally selective alpha2C adrenoreceptor agonists | ADRA2C, ADRB2, ADRA2A | KMT2A 1902/4885HSD11B1 522/4885KDM4E 3667/4885 |
| US-20070244055-A1 | Conjugates useful in the treatment of prostate cancer | BPHL, KLK3, DNPEP | KMT2A 213/4885HSD11B1 1766/4885KDM4E 1500/4885 |
| US-20070099872-A1 | Functionally selective alpha2C adrenoreceptor agonists | ADRA2C, ADRB2, ADRA2A | KMT2A 1902/4885HSD11B1 522/4885KDM4E 3667/4885 |
| US-20200262858-A1 | DERIVATIVES OF AMPHOTERICIN B | C9, ERG28, AMPD3 | KMT2A 4170/4885HSD11B1 2063/4885KDM4E 2646/4885 |
| US-20190276489-A1 | PROGESTERONE ANALOGS AND USES RELATED THERETO | PGR, SHBG, PGRMC1 | KMT2A 3136/4885HSD11B1 144/4885KDM4E 2553/4885 |
| US-20230131402-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | GRIN1, GRIN2A, GRIN3A | KMT2A 1591/4885HSD11B1 2081/4885KDM4E 2689/4885 |
| US-20070021350-A1 | Conjugates useful in the treatment of prostate cancer | BPHL, KLK3, DNPEP | KMT2A 213/4885HSD11B1 1766/4885KDM4E 1500/4885 |
| US-20070155776-A1 | THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS | ABL1, ERBB2, LCK | KMT2A 1305/4885HSD11B1 4731/4885KDM4E 1041/4885 |
| US-20080045496-A1 | PYRROLOTRIAZINE KINASE INHIBITORS | JAK2, NTRK2, NTRK3 | KMT2A 1500/4885HSD11B1 3510/4885KDM4E 1939/4885 |
| US-20230310551-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | INSR, GPR119, IRS1 | KMT2A 4174/4885HSD11B1 2587/4885KDM4E 4815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.