SCHEMBL1702407

SCHEMBL1702407

Nc1ccc([Si](Cl)(Cl)Cl)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
CYP3A4 P08684 6/20 0.43
TSHR P16473 5/20 0.43
MAPK1 P28482 3/20 0.43
ALDH1A1 P00352 7/20 0.42
TDP1 Q9NUW8 6/20 0.42
TP53 P04637 1/20 0.42
KDM4E B2RXH2 1/20 0.40
ALOX15 P16050 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HSD17B10 Q99714 2/20 0.38
ACHE P22303 1/20 0.38
LMNA P02545 1/20 0.38
CYP2D6 P10635 1/20 0.38
CHRM1 P11229 1/20 0.38
KCNA1 Q09470 1/20 0.38
CA3 P07451 1/20 0.38
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2119390 0.73 MEN1 (0.57) MAPTMEN1KMT2ACYP3A4TSHR
SCHEMBL134905 0.71 LMNA (0.53) MAPTCYP3A4TSHRMAPK1ALDH1A1
SCHEMBL28422604 0.71 TDP1 (0.42) MAPTMEN1KMT2ACYP3A4TSHR
SCHEMBL27981 0.71
SCHEMBL320609 0.71 MEN1 (1.00) MAPTMEN1KMT2ACYP3A4TSHR
SCHEMBL136168 0.69 TYR (0.41) MAPK1TP53KDM4ESMN1; SMN2LMNA
SCHEMBL4511521 0.69 MAPT (0.50) MAPTMEN1KMT2ACYP3A4TSHR
SCHEMBL1172568 0.69 MEN1 (0.50) MAPTMEN1KMT2ACYP3A4TSHR
SCHEMBL9165768 0.69 MEN1 (0.50) MAPTMEN1KMT2ACYP3A4ALDH1A1
SCHEMBL22694323 0.69 MEN1 (0.50) MAPTMEN1KMT2ACYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029108-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-02 US disclosed
US-11917902-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 US disclosed
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-18 US disclosed
US-11832507-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
CN-110660761-B Heat-conducting structure or semiconductor device 丰田自动车株式会社 2023-10-20 CN disclosed
US-20230337452-A1 PHOSPHORESCENCE-SENSITIZED DELAYED FLUORESCENCE LIGHT EMITTING SYSTEM UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-11793066-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-17 US disclosed
US-11716902-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-01 US disclosed
US-20230240130-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-07-27 US disclosed
US-11696459-B2 Phosphorescence-sensitized delayed fluorescence light emitting system UNIVERSAL DISPLAY CORPORATION (US) 2023-07-04 US disclosed
US-20110101856-A1 Ion-Pairing Soft Salts Based On Organometallic Complexes And Their Applications In Organic Light Emitting Diodes THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2011-05-05 US disclosed
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 US disclosed
US-20100187984-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORPORATION (US) 2010-07-29 US disclosed
US-7750175-B2 Organic light-emitting diodes and related hole transport compounds NORTHWESTERN UNIVERSITY (US) 2010-07-06 US disclosed
US-20100141127-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-06-10 US disclosed
US-20100072887-A1 ORGANOSELENIUM MATERIALS AND THEIR USES IN ORGANIC LIGHT EMITTING DEVICES UNIVERSAL DISPLAY CORPORATION 2010-03-25 US disclosed
US-20090284145-A1 Organic Light-Emitting Diodes and Methods for Assembly and Enhanced Charge Injection NATIONAL SCIENCE FOUNDATION 2009-11-19 US disclosed
US-20090284137-A1 ORGANIC LIGHT-EMITTING DIODES AND METHODS FOR ASSEMBLY AND EMISSION CONTROL NORTHWESTERN UNIVERSITY 2009-11-19 US disclosed
US-20090224657-A1 ORGANIC LIGHT-EMITTING DIODES AND METHODS FOR ASSEMBLY AND ENHANCED CHARGE INJECTION MARKS TOBIN J 2009-09-10 US disclosed
US-20070170844-A1 Organic light-emitting diodes and methods for assembly and emission control NORTHWESTERN UNIVERSITY 2007-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12029108-B2 Organic electroluminescent materials and devices LBR, DBF4, DNMT3A MAPT 4748/4885MEN1 3288/4885KMT2A 1873/4885
US-20100141127-A1 PHOSPHORESCENT EMITTERS PAICS, TYMP, NUDT1 MAPT 106/4885MEN1 2832/4885KMT2A 2445/4885
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, LBR, LDLR MAPT 3591/4885MEN1 2603/4885KMT2A 790/4885
US-20230240130-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBPL3, LBR, RBM3 MAPT 4148/4885MEN1 3165/4885KMT2A 3061/4885
US-11716902-B2 Organic electroluminescent materials and devices CYCS, NES, EML4 MAPT 1537/4885MEN1 2338/4885KMT2A 2419/4885
US-11793066-B2 Organic electroluminescent materials and devices EPCAM, ICMT, ORAI2 MAPT 1111/4885MEN1 935/4885KMT2A 3126/4885
US-11917902-B2 Organic electroluminescent materials and devices SOD1, NDUFV1, L1CAM MAPT 976/4885MEN1 933/4885KMT2A 3691/4885
US-20110101856-A1 Ion-Pairing Soft Salts Based On Organometallic Complexes And Their Applications In Organic Light Emitting Diodes OCIAD2, ICOSLG, OCIAD1 MAPT 1328/4885MEN1 1602/4885KMT2A 915/4885
US-20100072887-A1 ORGANOSELENIUM MATERIALS AND THEIR USES IN ORGANIC LIGHT EMITTING DEVICES SCLY, BZW2, GPX4 MAPT 1113/4885MEN1 2669/4885KMT2A 2845/4885
US-20100187984-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED DDT, FZD7, BRD7 MAPT 1289/4885MEN1 1427/4885KMT2A 816/4885
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX DDT, ICOSLG, PDCD1LG2 MAPT 744/4885MEN1 2576/4885KMT2A 3227/4885
US-11832507-B2 Organic electroluminescent materials and devices MLX, LBR, LDLR MAPT 3591/4885MEN1 2603/4885KMT2A 790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.