Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydroxyamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL28915675 | 1.00 | — | — | |
| Hydrazine SCHEMBL27794370 | 0.91 | — | — | |
| Hydroxyamine SCHEMBL18614724 | 0.89 | — | — | |
| Hydroxyamine SCHEMBL351722 | 0.89 | — | — | |
| Hydroxyamine SCHEMBL30786426 | 0.89 | — | — | |
| Hydroxyamine SCHEMBL1129 | 0.89 | — | — | |
| Hydroxyamine SCHEMBL482304 | 0.89 | — | — | |
| Hydroxyamine SCHEMBL1331311 | 0.89 | — | — | |
| Hydroxyamine SCHEMBL10610314 | 0.89 | — | — | |
| Hydroxyamine SCHEMBL3590179 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484644-A | Method for preparing, separating and enriching uranium from polyamidoxime/graphene nanoribbon composite aerogel | 东华理工大学 | 2020-08-04 | — | — | CN | claimed |
| CN-117549390-A | Oxime amine cellulose nanofiber filled nanometer wood and preparation method thereof | 中国科学院青岛生物能源与过程研究所 | 2024-02-13 | — | — | CN | disclosed |
| CN-116749567-A | Ultralight insole preparation equipment and process | 泉州源利鞋材有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-107771180-B | TGR5 modulators and methods of use thereof | 英特塞普特医药品公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-111484644-A | Method for preparing, separating and enriching uranium from polyamidoxime/graphene nanoribbon composite aerogel | 东华理工大学 | 2020-08-04 | — | — | CN | disclosed |
| US-9487538-B2 | Two-carbon linked artemisinin-derived trioxane dimers | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-11-08 | — | — | US | disclosed |
| US-20150361088-A1 | TWO-CARBON LINKED ARTEMISININ-DERIVED TRIOXANE DIMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-12-17 | — | — | US | disclosed |
| EP-2496551-B1 | A FACILE SYNTHESIS OF 3-AMINOPICRIC ACID | PACIFIC SCIENT ENERGETIC MATERIALS CO (US) | 2014-03-05 | — | — | EP | disclosed |
| US-8404897-B2 | Facile synthesis of 3-aminopicric acid | PACIFIC SCIENTIFIC ENERGETIC MATERIALS COMPANY (US) | 2013-03-26 | — | — | US | disclosed |
| EP-2496551-A1 | A FACILE SYNTHESIS OF 3-AMINOPICRIC ACID | Pacific Scientific Energetic Materials Company (US) | 2012-09-12 | — | — | EP | disclosed |
| EP-1677783-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | Nicholas Piramal India Limited (IN) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005035495-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2005-04-21 | — | — | WO | disclosed |
| CN-1168721-C | 5-cyano-2-aminopyrimidine derivatives | О | 2004-09-29 | — | — | CN | disclosed |
| CN-1419541-A | Pharmaceutically active pyrrolidine derivatives as BAX inhibitors | APPLIED RES SYSTEMS AKS HOLDIN (NL) | 2003-05-21 | — | — | CN | disclosed |
| CN-1370152-A | 5-cyano-2-aminopyrimidine derivatives | CELLETECH CHIROSCIENCE LTD (GB) | 2002-09-18 | — | — | CN | disclosed |
| WO-1999032445-A1 | OXIMINO-PIPERIDINE, -PYRROLIDINE AND -AZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MUSCARINIC RECEPTOR (ANT-)AGONISTS | ALCON LABORATORIES, INC. (US) | 1999-07-01 | — | — | WO | disclosed |
| US-5336789-A | Also insecticides, miticides, nematocides | AMERICAN CYANAMID COMPANY (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0238258-B1 | Macrolide compounds | AMERICAN CYANAMID CO (US) | 1994-01-26 | — | — | EP | disclosed |
| US-5185456-A | Insecticides, nematocids, miticides; antibiotics | AMERICAN CYANAMID COMPANY (US) | 1993-02-09 | — | — | US | disclosed |
| EP-0238258-A1 | Macrolide compounds | AMERICAN CYANAMID COMPANY (US) | 1987-09-23 | — | — | EP | disclosed |