Allylbenzene

Allylbenzene

SCHEMBL1809413

C=CCc1ccccc1.CN(C)C.Cl

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Allylbenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB known ✓ P27338 1/20 0.48
PPARG known ✓ P37231 1/20 0.38
GAA known ✓ P10253 1/20 0.38
CNR2 P34972 1/20 0.47
ALDH1A1 P00352 4/20 0.47
TSHR P16473 2/20 0.47
TP53 P04637 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
CYP3A4 P08684 2/20 0.47
ALOX15 P16050 1/20 0.47
ALOX12 P18054 1/20 0.47
AOC3 Q16853 2/20 0.41
TAAR1 Q96RJ0 1/20 0.41
CYP2C8 P10632 1/20 0.40
CYP2C18 P33260 1/20 0.40
CYP2C19 P33261 1/20 0.40
PPARD Q03181 1/20 0.38
PPARA Q07869 1/20 0.38
MGLL Q99685 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Allylbenzene SCHEMBL995541 0.98 MAOB (0.50) MAOBCNR2ALDH1A1TSHRTP53
Allylbenzene SCHEMBL28033453 0.91 MAOB (0.57) MAOBCNR2ALDH1A1TSHRTP53
Allylbenzene SCHEMBL5697714 0.91 MAOB (0.57) MAOBCNR2ALDH1A1TSHRTP53
Allylbenzene SCHEMBL1648511 0.88 MAOB (0.50) MAOBCNR2ALDH1A1TSHRTP53
Allylbenzene SCHEMBL5940129 0.88 MAOB (0.55) MAOBCNR2ALDH1A1TSHRTP53
Allylbenzene SCHEMBL28198945 0.88 MAOB (0.55) MAOBCNR2ALDH1A1TSHRTP53
Allylbenzene SCHEMBL21274 0.88
Allylbenzene SCHEMBL2478260 0.88 MAOB (0.60) MAOBCNR2ALDH1A1TSHRTP53
Allylbenzene SCHEMBL10325179 0.88 MAOB (0.60) MAOBCNR2ALDH1A1TSHRTP53
Allylbenzene SCHEMBL254037 0.86 CYP3A4 (0.48) MAOBCNR2ALDH1A1TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108508719-B Toner and image forming apparatus 佳能株式会社 2022-11-15 CN disclosed
CN-108508719-A Toner 佳能株式会社 2018-09-07 CN disclosed
CN-104937012-A Method for producing resin particle dispersion liquid and method for producing toner for developing electrostatic image KAO CORP 2015-09-23 CN disclosed
US-8592121-B2 Electrostatic image developing toner for pressure fixing, production method of the same, electrostatic image developer, image forming method and image forming apparatus FUJI XEROX CO., LTD. (JP) 2013-11-26 US disclosed
CN-101782727-B Electrostatic image developing carrier, electrostatic image developer,and image forming method FUJI XEROX CO LTD 2013-04-24 CN disclosed
CN-101655674-B Electrostatic-image-developing toner, process for producing electrostatic-image-developing toner, electrostatic image developer, image-forming method, and image-forming apparatus FUJI XEROX CO LTD 2013-03-27 CN disclosed
CN-101373346-B Electrostatic image developing toner, electrostatic image developer, toner cartridge, process cartridge and image forming apparatus FUJI XEROX CO LTD 2012-06-27 CN disclosed
CN-101075100-B Toner for developing electrostatic images, electrostaic image development and imaging method thereof FUJITSU XEROX CORP 2012-03-14 CN disclosed
CN-102200703-A Electrostatic latent image developing toner, electrostatic latent image developer, toner cartridge, process cartridge and image forming apparatus FUJI XEROX CO LTD 2011-09-28 CN disclosed
US-7989130-B2 Electrostatic latent image developing toner, manufacturing method for electrostatic latent image developing toner, electrostatic latent image developing developer, and image forming method FUJI XEROX CO., LTD. (JP) 2011-08-02 US disclosed
EP-1734009-A1 Wastewater treatment process FUJI XEROX CO., LTD. (JP) 2006-12-20 EP disclosed
US-7094514-B2 developing an electrostatic latent image formed on an electrophotographic photoreceptor with a toner for development containing a binder resin and a colorant, the surface of the photoreceptor contains a compound with a double bond, the surface of the toner has metal oxide or metal nitride particle FUJI XEROX CO., LTD. (JP) 2006-08-22 US disclosed
US-20060115757-A1 Toner for development of electrostatic latent image, electrostatic latent image developer, and method for formation of image FUJI XEROX CO., LTD. (JP) 2006-06-01 US disclosed
CN-1752854-A Electrostatic latent image developing toner, developer and method of producing the electrostatic latent image developing toner FUJI XEROX CO LTD (JP) 2006-03-29 CN disclosed
US-20060063087-A1 Electrostatic latent image developing toner, developer and method of producing the electrostatic latent image developing toner FUJI XEROX CO., LTD. (JP) 2006-03-23 US disclosed
US-20060046178-A1 Electrostatic latent image developing magenta toner, electrostatic latent image developer, toner manufacturing method, and image forming method FUJI XEROX CO., LTD. (JP) 2006-03-02 US disclosed
CN-1739068-A Toner, process for producing the same, two-component developing agent and method of image formation MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2006-02-22 CN disclosed
US-20050181295-A1 Electrostatic latent image developing toner, and method for manufacturing electrostatic latent image developer and electrostatic latent image developing toner FUJI XEROX CO., LTD. (JP) 2005-08-18 US disclosed
US-20040185367-A1 Image forming method FUJI XEROX CO., LTD. (JP) 2004-09-23 US disclosed
CN-1479870-A Optical detection of glucose using boronic acid adducts ���������Ǵ�ѧ���»� 2004-03-03 CN disclosed