Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28686879 | 1.00 | TSHR (0.31) | TSHR | |
| Hydrochloric Acid SCHEMBL10994758 | 1.00 | TSHR (0.31) | TSHR | |
| SCHEMBL3819026 | 0.96 | TSHR (0.33) | TSHR | |
| SCHEMBL15141 | 0.96 | TSHR (0.33) | TSHR | |
| Water SCHEMBL9076546 | 0.92 | TSHR (0.31) | TSHR | |
| SCHEMBL10403680 | 0.92 | TSHR (0.31) | TSHR | |
| Lithium SCHEMBL29677311 | 0.92 | TSHR (0.31) | TSHR | |
| SCHEMBL1845985 | 0.92 | TSHR (0.31) | TSHR | |
| SCHEMBL11774941 | 0.92 | TSHR (0.31) | TSHR | |
| Ammonia Solution, Strong SCHEMBL6309484 | 0.92 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116239494-A | Ligand compound and preparation method thereof, catalyst composition and application, catalyst and polyethylene elastomer and preparation method and application thereof | 浙江巨化技术中心有限公司 | 2023-06-09 | — | — | CN | claimed |
| EP-1230024-A4 | POLYMERIZATION CATALYST SYSTEMS, METHODS OF MAKING AND USES THEREFOR | CONOCOPHILLIPS CO (US) | 2004-09-29 | — | — | EP | claimed |
| US-20040132929-A1 | Olefin polymerization processes and products thereof | MARTIN JOEL L (US) | 2004-07-08 | — | — | US | claimed |
| US-20030171510-A1 | Polymerization catalyst systems, methods of making and uses therefor | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2003-09-11 | — | — | US | claimed |
| EP-1230024-A1 | POLYMERIZATION CATALYST SYSTEMS, METHODS OF MAKING AND USES THEREFOR | Phillips Petroleum Company (US) | 2002-08-14 | — | — | EP | claimed |
| US-20020035228-A1 | Olefin polymerization processes and products thereof | PHILLIPS PETROLEUM COMPANY | 2002-03-21 | — | — | US | claimed |
| WO-2001032309-A1 | POLYMERIZATION CATALYST SYSTEMS, METHODS OF MAKING AND USES THEREFOR | PHILLIPS PETROLEUM COMPANY (US) | 2001-05-10 | — | — | WO | claimed |
| US-6034186-A | LOOP, SLURRY POLYMERIZATION IN PRESENCE OF HYDROCARBON DILUENT; HIGH MOLECULAR WEIGHT POLYETHYLENE | PHILLIPS PETROLEUM COMPANY (US) | 2000-03-07 | — | — | US | claimed |
| EP-0909769-A2 | Olefin polymerization processes and products thereof | PHILLIPS PETROLEUM COMPANY (US) | 1999-04-21 | — | — | EP | claimed |
| CN-1214343-A | Olefin polymerization processes and products thereof | PHILLIPS PETROLEUM CO (US) | 1999-04-21 | — | — | CN | claimed |
| EP-0878490-A2 | Olefin polymerization processes and products thereof | PHILLIPS PETROLEUM COMPANY (US) | 1998-11-18 | — | — | EP | claimed |
| EP-0599485-B1 | Method of inhibiting corrosion in aqueous systems | BETZ EUROP INC (US) | 1996-06-26 | — | — | EP | claimed |
| CN-118307692-A | Preparation method and application of organic acid rare earth compound | 中国石油天然气股份有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-117886982-A | Catalyst component and catalyst for olefin polymerization, and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| US-11920007-B2 | Process for producing ultrahigh molecular weight polymer in powder form | INDIAN OIL CORPORATION LIMITED (IN) | 2024-03-05 | — | — | US | disclosed |
| CN-117430751-A | Trans-polycyclopentene polymerization catalyst system and preparation and application of trans-polycyclopentene | 中国石油天然气股份有限公司 | 2024-01-23 | — | — | CN | disclosed |
| US-5494982-A | TWO STEP POLYMERIZATION IN PRESENCE OF CATALYST OBTAINED FROM SOLID CATALYST CONTAINING MAGNESIUM, TITANIUM, ZIRCONIUM AND HALOGEN, ORGANOALUMINUM COMPOUND | IDEMITSU PETROCHEMICAL COMPANY, LIMITED (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0398350-A2 | Process for preparing ethylenic polymer compositions | IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) | 1990-11-22 | — | — | EP | disclosed |
| EP-0101978-B1 | OLEFIN POLYMERIZATION | PHILLIPS PETROLEUM COMPANY (US) | 1986-10-29 | — | — | EP | disclosed |
| EP-0101978-A1 | Olefin polymerization | PHILLIPS PETROLEUM COMPANY (US) | 1984-03-07 | — | — | EP | disclosed |