SCHEMBL18459121

SCHEMBL18459121

Ic1nc(I)c2ccccc2n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.44
ALDH1A1 P00352 5/20 0.44
HPGD P15428 4/20 0.44
GLA P06280 3/20 0.44
HSD17B10 Q99714 3/20 0.44
MAOA P21397 2/20 0.44
CASP1 P29466 2/20 0.44
CASP7 P55210 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CHRM2 P08172 1/20 0.44
ADRA2A P08913 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
CHRM1 P11229 1/20 0.44
NQO2 P16083 1/20 0.44
DRD1 P21728 1/20 0.44
ACHE P22303 1/20 0.44
SLC6A2 P23975 1/20 0.44
ADRA1A P35348 1/20 0.44
OPRM1 P35372 1/20 0.44
KCNH2 Q12809 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20319870 0.79 MAOA (0.54) KDM4EALDH1A1HPGDGLAHSD17B10
SCHEMBL18388687 0.78 GPR3 (0.54) KDM4EALDH1A1HPGDGLAHSD17B10
SCHEMBL18574483 0.77 GPR3 (0.59) KDM4EALDH1A1HPGDGLAHSD17B10
SCHEMBL17508358 0.77 MAOA (0.52) KDM4EALDH1A1HPGDGLAHSD17B10
SCHEMBL18544725 0.77 LMNA (0.52) KDM4EALDH1A1HPGDGLAHSD17B10
SCHEMBL16919331 0.76 ADORA2A (0.60) KDM4EALDH1A1HPGDGLAMAPT
SCHEMBL3590713 0.76 CYP1A1 (0.56) TDP1KMT2ACYP1A2CYP1A1CYP1B1
SCHEMBL22349585 0.74 TYMS (0.41) MAPTCYP1A2CYP1A1CYP1B1
SCHEMBL24015454 0.73 ALDH1A1 (0.47) KDM4EALDH1A1HPGDSMN1; SMN2MAPT
SCHEMBL12322126 0.73 CYP1A2 (0.61) KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11818932-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-14 US disclosed
US-20230363260-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-09 US disclosed
US-11793063-B2 Condensed-cyclic compound and organic light emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-17 US disclosed
US-11744146-B2 Amine-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-29 US disclosed
US-11730053-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-15 US disclosed
US-11706973-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-18 US disclosed
US-11696496-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-04 US disclosed
US-11690289-B2 Organic compound containing heterocyclic ring and having low lumo properties, and organic electroluminescent device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-27 US disclosed
US-11678498-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-13 US disclosed
US-11653563-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-16 US disclosed
US-9601699-B2 Chrysene-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-21 US disclosed
US-20170077419-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-16 US disclosed
US-20170077422-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) 2017-03-16 US disclosed
US-20170069847-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Research & Business Foundation Sungkyunkwan University (KR) 2017-03-09 US disclosed
US-20170069850-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-09 US disclosed
US-20170062720-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-02 US disclosed
US-20170062727-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-02 US disclosed
US-20170054091-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-23 US disclosed
US-20170054085-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-23 US disclosed
US-20170033297-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170062720-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LRRK2, SLC18A1, CCNT1 KDM4E 1389/4885ALDH1A1 832/4885HPGD 3585/4885
US-11793063-B2 Condensed-cyclic compound and organic light emitting device including the same CRY1, CRY2, CCNE2 KDM4E 3787/4885ALDH1A1 518/4885HPGD 1827/4885
US-11706973-B2 Condensed cyclic compound and organic light-emitting device including the same C1S, CCNT1, C9 KDM4E 4384/4885ALDH1A1 246/4885HPGD 2600/4885
US-11690289-B2 Organic compound containing heterocyclic ring and having low lumo properties, and organic electroluminescent device using the same LEF1, PPOX, LIMK1 KDM4E 1153/4885ALDH1A1 111/4885HPGD 1134/4885
US-20170033297-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CCNE2, CCNE1, CCNA1 KDM4E 3740/4885ALDH1A1 275/4885HPGD 1650/4885
US-20170077422-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNE2, LAGE3 KDM4E 1342/4885ALDH1A1 205/4885HPGD 1397/4885
US-11744146-B2 Amine-based compound and organic light-emitting device including the same AOC2, AOC1, EML4 KDM4E 655/4885ALDH1A1 76/4885HPGD 3979/4885
US-20170077419-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME OCIAD1, OXA1L, CYP1A1 KDM4E 3224/4885ALDH1A1 202/4885HPGD 913/4885
US-20170069847-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 KDM4E 3395/4885ALDH1A1 406/4885HPGD 1490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.