Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.37 |
| ▸ | LCK known ✓ | P06239 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7037743 | 1.00 | HTT (0.43) | HTTKMT2AKDM4EMAPTPOLB | |
| SCHEMBL6040109 | 0.97 | HTT (0.45) | HTTKMT2AKDM4EMAPTPOLB | |
| SCHEMBL5893 | 0.97 | — | — | |
| SCHEMBL5894 | 0.97 | — | — | |
| SCHEMBL28517 | 0.97 | — | — | |
| SCHEMBL27531633 | 0.97 | HTT (0.45) | HTTKMT2AKDM4EMAPTPOLB | |
| SCHEMBL623803 | 0.97 | HTT (0.45) | HTTKMT2AKDM4EMAPTPOLB | |
| SCHEMBL623108 | 0.97 | HTT (0.45) | HTTKMT2AKDM4EMAPTPOLB | |
| SCHEMBL8089680 | 0.94 | HTT (0.43) | HTTKMT2AKDM4EMAPTPOLB | |
| SCHEMBL10685484 | 0.94 | HTT (0.43) | HTTKMT2AKDM4EMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3162819-B1 | IMPROVED ZIEGLER-NATTA CATALYST SYNTHESIS AND PROCESS THEREOF | INDIAN OIL CORP LTD (IN) | 2018-09-05 | — | — | EP | claimed |
| US-9896523-B2 | Ziegler-Natta catalyst synthesis and process thereof | INDIAN OIL CORPORATION LIMITED (IN) | 2018-02-20 | — | — | US | claimed |
| EP-3162819-A1 | IMPROVED ZIEGLER-NATTA CATALYST SYNTHESIS AND PROCESS THEREOF | Indian Oil Corporation Limited (IN) | 2017-05-03 | — | — | EP | claimed |
| US-20160376384-A1 | ZIEGLER-NATTA CATALYST SYNTHESIS AND PROCESS THEREOF | INDIAN OIL CORPORATION LIMITED (IN) | 2016-12-29 | — | — | US | claimed |
| EP-3050906-B1 | CATALYST PROCESS MODIFICATION AND POLYMERIZATION THEREOF | INDIAN OIL CORP LTD (IN) | 2020-07-22 | — | — | EP | disclosed |
| EP-3162819-B1 | IMPROVED ZIEGLER-NATTA CATALYST SYNTHESIS AND PROCESS THEREOF | INDIAN OIL CORP LTD (IN) | 2018-09-05 | — | — | EP | disclosed |
| US-9896523-B2 | Ziegler-Natta catalyst synthesis and process thereof | INDIAN OIL CORPORATION LIMITED (IN) | 2018-02-20 | — | — | US | disclosed |
| US-9873752-B2 | Catalyst process modification and polymerization thereof | INDIAN OIL CORPORATION LTD. (IN) | 2018-01-23 | — | — | US | disclosed |
| EP-3162819-A1 | IMPROVED ZIEGLER-NATTA CATALYST SYNTHESIS AND PROCESS THEREOF | Indian Oil Corporation Limited (IN) | 2017-05-03 | — | — | EP | disclosed |
| US-20160376384-A1 | ZIEGLER-NATTA CATALYST SYNTHESIS AND PROCESS THEREOF | INDIAN OIL CORPORATION LIMITED (IN) | 2016-12-29 | — | — | US | disclosed |
| EP-3050906-A1 | CATALYST PROCESS MODIFICATION AND POLYMERIZATION THEREOF | Indian Oil Corporation Limited (IN) | 2016-08-03 | — | — | EP | disclosed |
| US-20160215077-A1 | CATALYST PROCESS MODIFICATION AND POLYMERIZATION THEREOF | INDIAN OIL CORPORATION LTD. (IN) | 2016-07-28 | — | — | US | disclosed |
| EP-0426140-A2 | Process for the preparation of random copolymers | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) | 1991-05-08 | — | — | EP | disclosed |
| EP-0426139-A2 | Process for the preparation of random copolymers | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) | 1991-05-08 | — | — | EP | disclosed |
| US-4983562-A | CATALYST PRECURSOR CONTAINING MAGNESIUM, TITANIUM, HALOGEN, ELECTRON DONOR AND CERIUM COMPOUND; HYDROCARBYLALUMINUM COCATALYST; SELECTIVITY CONTROL AGENT | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0361371-A2 | Process for the preparation of alphaolefin polymers | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (a New York corporation) (US) | 1990-04-04 | — | — | EP | disclosed |
| CN-1038651-A | The preparation method of random copolymers | UNION CARBIDE CORP (US) | 1990-01-10 | — | — | CN | disclosed |
| EP-0341724-A1 | Process for the preparation of random copolymers | UNION CARBIDE CORPORATION (US) | 1989-11-15 | — | — | EP | disclosed |
| EP-0340688-A2 | Process for the preparation of high purity alpha-olefin polymers | UNION CARBIDE CORPORATION (US) | 1989-11-08 | — | — | EP | disclosed |
| EP-0291958-A2 | Process for producing stereoregular polymers having a narrow molecular weight distribution | UNION CARBIDE CORPORATION (US) | 1988-11-23 | — | — | EP | disclosed |